Michal Holčapek

Research interests: lipidomic analysis, UHPLC/MS, UHPSFC/MS, mass spectrometry, cancer biomarkers

[Jan Broder Engler @JanBroderEngler]

Thank you for citing #tidyplots 🙏

Jakub Idkowiak et al. Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data. Nature Communications (2025).

https://t.co/QfFivsjK69

#rstats #dataviz #phd

[Kermit Murray @kermitmurray]

A lipidomics roadmap: from basic research to societal challenges https://t.co/zaTlNNh74L (RSS) #nature #MassSpecRSS

[Lesley Goodburn @lgoodbu]

Pilot study of screening method for pancreatic cancer using lipidomic profiling of plasma or serum | Communications Medicine https://t.co/omM4OyXGPl

[Holčapkovic @holcapkovi54219]

🌟 We are thrilled to announce that another article has just been published in @an_chem
Our study, presents a robust and high-throughput workflow for quantifying less polar lipid species in complex biological samples. 🧪✨
https://t.co/YzDlb6LqVZ
#lipidomics #massspectrometry

[Holčapkovic @holcapkovi54219]

🚀 New paper out!
Our study “Enhancing metabolite coverage using dedicated individual polarity modes in HILIC-MS” is now published in ABC!🙌

https://t.co/tlvHfkU9y8

[Univerzita Pardubice @UniPardubice]

3/3📘 Published by the International Lipidomics Society in Science Signaling (May 20, 2025).
👉 DOI: 10.1126/scisignal.adw1245
#health #massspectrometry #UPCE

[Univerzita Pardubice @UniPardubice]

2/3🔬 The recommendations aim to improve reproducibility in LC-MS/MS analysis, a technique that detects 200+ lipid species in one run. Oxylipins also help explain how common drugs like aspirin work. #research #science

[Univerzita Pardubice @UniPardubice]

1/3🧪 New guidelines for analyzing oxylipins – fatty molecules linked to inflammation, cancer & dementia – were developed by nearly 100 scientists from 70+ institutions worldwide. These lipids are crucial for health and notoriously hard to measure. #lipidomics #UPCE

[Lenka Dub @DubLenka10222]

Novel Charge-Switch Derivatization Method Using 3-(Chlorosulfonyl)benzoic Acid for Sensitive RP-UHPLC/MS/MS Analysis of Acylglycerols, Sterols, and Prenols | Analytical Chemistry https://t.co/tWniZzn3jh

[Michal Holčapek @holcapek]

@DarPutinovi

[Michal Holčapek @holcapek]

Our new article in Analytical Chemistry unveils breakthrough 4D UHPLCxUHPSFC/MS/MS method for comprehensive detection of lipids:
https://t.co/7d9Z4XxgTQ

[Univerzita Pardubice @UniPardubice]

Aktivuje prospěšný receptor CAR a blokuje škodlivé účinky PXR. Studie na myších ukázala skvělé výsledky a objev publikoval prestižní časopis Nature Communications. (3/3) https://t.co/M5d9BhHvR7

[Baker Institute OAR @BakerResOAR]

Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards
https://t.co/MpF3A2KaWD

[Michal Holčapek @holcapek]

Our cooperation with Petr Pávek group resulted in Nat Commun paper:
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model
https://t.co/02kWCTR1WR

[Michal Holčapek @holcapek]

New article on our software is available online
Lipid Quant 2.1: open-source software for identification and quantification of lipids measured by lipid class separation QTOF high-resolution mass spectrometry methods:
https://t.co/aVvSAgiW0R

[Michal Holčapek @holcapek]

Our review article "Recent Advances, Challenges, and Future Directions in the Mass Spectrometry Analysis of Glycosphingolipids in Biological Samples" is now available online:
https://t.co/cpPvlzcYAu

[Michal Holčapek @holcapek]

Our new article "HILIC/MS quantitation of low-abundant phospholipids and sphingolipids in human plasma and serum: Dysregulation in pancreatic cancer" is just published: https://t.co/0mxvyJMZdV

[Michal Holčapek @holcapek]

Our new paper is on complex characterization of GSL is published: https://t.co/8V4CeC6sXL

[IMSC2022 @imsc2022]

The third award of today: the first Jochen Franzen award: Shane Ellis @EllisMSILab @MolHorizons @UOW
Congratulations!

@BrukerMassSpec @bruker @anzsms @denvms @TheIMSF

[Kermit Murray @kermitmurray]

Introducing the Lipidomics Minimal Reporting Checklist https://t.co/blwM7k7XtX #nature #MassSpecPub