RFdiffusion2 now available! Atomic-level scaffolding for complex active sites
Available on @tamarindbio now.
RFdiffusion2 shows state-of-the-art atomic-level scaffolding that generalizes to complex, multi-island active sites, and it reliably yields active enzymes with modest screening, though activities are still below the best native enzymes and should improve with richer theozymes and sequence/pocket co-design.
I’ve been beta testing @GoogleAI Co-Scientist for some time. It generates novel ideas, hypotheses & scientific proposals. It’s unbelievably good; together with the other AI models I discuss here, it fundamentally changes how science is done & will make the world a better place!❤️