Howard Chang

[Cell @CellCellPress]

Now online! EcDNA-borne structural variants drive oncogenic fusion transcript amplification https://t.co/rYA8TEaZNH

[Julia Belk @juliabelk]

Happy to share our paper describing SPACE-seq - a new approach to spatial multiomics and lineage tracing - out today in @PNASNews! 🧵(1/5)

https://t.co/bzTm0fqasH

[UK Biobank @uk_biobank]

Today we’re launching the world’s most comprehensive study of proteins circulating in our bodies, which will transform research into new medical tests, drugs and treatments.

Discover more: https://t.co/o8t2yuknLv

[William J. Greenleaf @WJGreenleaf]

Incredibly excited that our paper linking single molecule states of TF binding to gene expression using quantitative thermodynamic models is out in Nature today. An amazing collaboration with the Bintu Lab. Congrats to Ben, Michaela, and Julia! https://t.co/4zjMOlOgVV

[Howard Chang @HowardYChang]

I am excited to join storied biotech pioneer @Amgen as Chief Scientific Officer and Head of Research. I look forward to partnering with my new colleagues to deepen understanding of biology and develop solutions to the most pressing medical challenges https://t.co/Vqmsv68Q9Z

[Cancer Grand Challenges @CancerGrand]

Today #CancerGrandChallenges team eDyNAmiC and their international collaborators published 3️⃣ papers in
@Nature 📣

They show the prevalence of ecDNA in cancer, identify fundamental mechanisms and an actionable target now being tested in the clinic.

More: https://t.co/lx5dtVlyDK

[Howard Chang @HowardYChang]

@AsifaAkhtar1 Congratulations Asifa!!

[Howard Chang @HowardYChang]

@TheCrick @embl Congratulations Edith and @TheCrick !

[Howard Chang @HowardYChang]

@HHMINEWS @FNIH_Org I am grateful and very honored for this recognition. Many thanks to my collaborators, trainees, and mentors for their wisdom and support.

[Cell Press @CellPressNews]

"Pathways for macrophage uptake of cell-free circular RNAs"

Read more in @MolecularCell
https://t.co/MzsB5fi7M4

@StanfordMed @HowardYChang

[Nature Biotechnology @NatureBiotech]

Bidirectional epigenetic editing reveals hierarchies in gene regulation https://t.co/IziHMe3bsx

[Howard Chang @HowardYChang]

@the_asci I am grateful and humbled by this honor, especially for mentorship. Thank you to my own mentors, collaborators, and all the trainees who lifted me up.

[Jay Bradner, M.D. @jaybradner]

“Consensus changing” chemical biology at its finest, a new approach to modulating gene control. Neormorphic covalent ligands redirect the intently studied FOXA1 transcription factor, and instruct on pioneering functionality. A first TF-DNA glue? Way to go @Michael_A_Erb and Ben Cravatt.

[Anton Henssen @anton_gh]

Beautiful review article on ecDNA in @NatureRevCancer by @HowardYChang @mischellab !!

🔥🔥👇🏻👇🏻
https://t.co/TXPMSXrpMM

[Diana Dou @DianaRDou]

Excited to share that our paper is out in @CellCellPress! We "lnc" Xist ribonuceloproteins (RNPs) to the greater prevalence of autoimmune diseases in biological females.
A wonderful multi-institutional collaboration with @HowardYChang and many others! https://t.co/O2CqO82qA9

[Howard Chang @HowardYChang]

Delighted to be honored by the King Faisal Prize. I am deeply grateful for all my mentors, collaborators, supporters, and especially lab members former and present.
https://t.co/Uud575J5ri

[Connor Tsuchida @connortsuchida]

Very excited to see our paper with @doudna_lab @yimmieg @carlhjune @HowardYChang @BrandesNadav out in @CellCellPress !! Obligatory tweet-orial (X-torial??) coming soon...

https://t.co/8TE5ssCKjm

[William J. Greenleaf @WJGreenleaf]

Huge congrats to Jason Buenrostro, who was just named a MacArthur Fellow! Fantastic news!

[Howard Chang @HowardYChang]

@CharlesSwanton @NatureMedicine @TakKarasaki @davidallanmoore @NickyMcGranahan @MariamJHanjani @SwantonLab Congrats to the TRACERx team for this remarkable set of papers!

[Jens Luebeck @Jens_Luebeck]

So when does ecDNA arise, exactly?

Our study on #ecDNA and the transformation of pre-cancerous Barrett’s esophagus into cancer is out today. This collaboration brought together @Team_eDyNAmiC, @RFitzgerald_lab and the @FredHutch Seattle Barrett’s Study.🧵
https://t.co/TbDNCl4LJV