Hughes Lab - UCI

The Hughes Lab at UCI. Developing blood vessels-on-a-chip and vascularized micro-organ (VMO) technologies to study vascular biology, cancer, and rare diseases.

[Hughes Lab - UCI @HughesLabUCI]

Check out our 2nd place @NikonSmallWorld video. Images in our vascularized micro-tumor device, it shows microvessels (red) forming over time and growing micro tumors (cyan) as they respond to contact with those vessels.

[BBC Science Focus Magazine @sciencefocus]

This time-lapse video shows a human micro-tumour growing over 10 days in a lab. 🤯

The tumour, in blue, grows with the support of vessels, shown in red.

Dr Stephanie Hachey and Dr Christopher Hughes were awarded second place for their video. @NikonSmallWorld @HughesLabUCI

[Wayne Orr @A_WayneOrr]

Any cardiovascular postdocs looking for a job? A tenure-track faculty position for cardiovascular research is open at LSU Health Shreveport. Excellent research infrastructure in a collaborative and supportive environment. Great place to start a lab.
https://t.co/l10dZuEBrU

[Maike Sander & Lab @msanderlab]

Excited to share our organoid model of vascularized stem cell islets.
Great teamwork led by @KVyNguyenNgoc and Yesl Jun. Thanks to @someshtweet, @HughesLabUCI, @steven_c_george, @ChristmanLab, @Hugh_Bender, @KravetsVira, @HIRN_CC .  1/4
https://t.co/9P6ZLSBEQ7

[Hughes Lab - UCI @HughesLabUCI]

@HaoYin20 Thank you so much!

[Hughes Lab - UCI @HughesLabUCI]

Our postdoc Steph is participating in the Anti Cancer Challenge at UCI this year to support junior scientists through @ARCS_OC. If you can take a couple minutes and make a donation to our cause Steph would be very grateful!

https://t.co/XVBYpPng2e

[Hughes Lab - UCI @HughesLabUCI]

Our postdoc Jenn presenting our work on the HHT-on-a-Chip model at last night’s MPS-World Summit! Thanks to everyone for stopping by!

[The Fang Lab @Fang_Lab]

Thrilled to have the opportunity to partner with @AracariBio @HughesLabUCI this week at #2022MPSWorldSummit to present a workshop to trainees discussing ways to allow physiology to inform development of micro physiological systems, and to demo the VMO platform!

[Hughes Lab - UCI @HughesLabUCI]

From left to right: Will, Chris, Sebastian and Makena — all incredibly talented grad students and enthusiastic scientists!

[Hughes Lab - UCI @HughesLabUCI]

Congratulations to our graduate students who presented an incredible joint poster at tonight’s MPS-World poster session!

[Hughes Lab - UCI @HughesLabUCI]

Our lab also has posters in Poster Session II on Thursday 6-8pm. We would love for you to come by and introduce yourself!

[Hughes Lab - UCI @HughesLabUCI]

We hope you were able to see our post doc Jenn this morning presenting a joint demo of our platform along with Will from @AracariBio!

[Hughes Lab - UCI @HughesLabUCI]

Are you in New Orleans this week for the MPS-World Summit? So are we! Most of our lab is in town and we are presenting several posters and talks about our work! Please come by and say hi!

https://t.co/sutrenx8O8

[Hughes Lab - UCI @HughesLabUCI]

In the first poster session, which will be Wednesday evening 6-8, we have several graduate student posters highlighting recent work on several of our healthy and disease #MPS models. Please stop by!

[Hughes Lab - UCI @HughesLabUCI]

Are you in New Orleans this week for the MPS-World Summit? So are we! Most of our lab is in town and we are presenting several posters and talks about our work! Please come by and say hi!

https://t.co/sutrenx8O8

[Hughes Lab - UCI @HughesLabUCI]

Thank you so much @HIRN_CC for highlighting our work to develop a Vascularized islet-on-a-chip model, the culmination of many years of work by our team!

@Hugh_Bender @msanderlab @steven_c_george @KimVyNguyenNgo1

[HIRN @HIRN_CC]

Highlighting #HIRN manuscript:

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction @biorxivpreprint https://t.co/NSdWEZrR7v

@allysonshughes @KimVyNguyenNgo1 @steven_c_george @msanderlab @HughesLabUCI

#HIRNFundedResearch

[Hughes Lab - UCI @HughesLabUCI]

Thank you! We are so excited to share this incredible work by our talented postdoc @Hugh_Bender!

[Yassi Aghazadeh @Yassi_ag]

Wonderful islet on a chip platform elevating islet culture conditions to include the #vasculature which provides functional support and models immune cell extravasation. Congratulations @Hugh_Bender @HughesLabUCI @msanderlab

[Maike Sander & Lab @msanderlab]

@BlumLabWisc @JimJohnsonSci We agree @BlumLabWisc ! It’s been fun to develop this together with @HughesLabUCI led by @Hugh_Bender .

[Hughes Lab - UCI @HughesLabUCI]

Congratulations to our postdoc Satomi Matsumoto for receiving an Outstanding Talk award at this year’s #NAVBO @vascularbiology!

[NAVBO @vascularbiology]

➡️Outstanding Talk in the Vascular Matrix Biology and Bioengineering Workshop

Suhaas Anbazhakan @suhaasaz
Kaveeta Kaw from @DiannaMilewicz Lab
Satomi Matsumoto from @HughesLabUCI
Scott Paulissen @ScottPaulissen
Michael Warkala @mwarkala

[Hughes Lab - UCI @HughesLabUCI]

Thank you! So excited to share our ideas!

[Hao Yin @HaoYin20]

Partial #EndMT & #Angiogenesis

"Why do EndoMT transcription factors appear to be more essential in pathological angiogenesis compared to during development..."

An insightful review from Dr. Christopher Hughes lab🤓

@HughesLabUCI @FrontCellDevBio 2021
https://t.co/WBQP5blsCL

[Hughes Lab - UCI @HughesLabUCI]

We’re so excited to present our latest work at @navbo #navbo2021 this week and hope you find this thread helpful in finding our research group members at the conference! Come say hi - we’d love to talk with you about our work!

[Hughes Lab - UCI @HughesLabUCI]

Are you at @vascularbiology 2021 starting this week? Here’s where you can check out the latest work from the Hughes lab!

[Hughes Lab - UCI @HughesLabUCI]

And last but certainly not least, don’t miss our illustrious leader Dr Chris Hughes when he co-chairs the Patterning and Morphogenesis I session tomorrow 10/27 at 2:00pm EST / 11:00am PST!