Sam Lambert

🇨🇦 in UK. Assistant Prof studying polygenic scores & multimorbidity @Cambridge_Uni/@PGSCatalog /@ChurchillCol. PhD studying TFs @UofT. Views are my own.

[Sam Lambert @iamslambert]

Interested in using multi-omics imputation or TWAS/PWAS approaches? Frustrated by the models being spread across multiple resources? Enter OmicsPred: a centralised resource for genetic prediction of multi-omic traits!

🔗 : https://t.co/5mM0VcVqkx
📃 : https://t.co/tbV1OHK68I

[Sam Lambert @iamslambert]

@gamzeandgursoy @Cambridge_Uni Welcome to Cambridge 👋

[BHF Cardiovascular Epidemiology Unit at Cambridge @CAMBRIDGE_CEU]

🚨 Funded PhD Opportunity (Oct 2026 start)

10 funded 4-year PhD studentships are available through @TheBHF doctoral training programme focused on preventing cardiovascular disease through innovative, data-driven approaches

For more info & how to apply: https://t.co/zGFoM1UXEN

[Eric Topol @EricTopol]

It's very hard to prevent vasovagal reactions, such as fainting, as evidenced from this study of nearly 1.4 million blood donors
https://t.co/WCluj5OJ4x

[PGS Catalog @PGSCatalog]

We hope it's easy to use with tutorials for UKB (https://t.co/ZakblQygD6) & All of Us (https://t.co/FVW0QK6OlR )! But feel free to contact us on Github: https://t.co/QZJi9rnl3k!

With that, happy holidays from the PGS Catalog team! 🎁 🎄

[PGS Catalog @PGSCatalog]

The new alpha only implements PGS scoring at the moment, but the roadmap will reimplement our existing genetic ancestry tools! Lot's of under-the-hood optimisation using python (zarr, dash), and it only takes VCF or BGEN input atm. https://t.co/sDtiTYBPbq

[PGS Catalog @PGSCatalog]

Wish it was easier to calculate PGS in trusted research environments (TRE) like DNAnexus or the All of Us workbench? Us to! We've been hard at work on a new version of pgsc_calc to make it more scalable in those TREs! Introducing pgsc_calc v3.0.0-alpha.1: https://t.co/4nQaIaeAT9

[BHF Cardiovascular Epidemiology Unit at Cambridge @CAMBRIDGE_CEU]

New paper in @ESC_Journals

@sritchie73 & colleagues found integrating genetic & metabolic blood tests with existing clinical data could enhance how doctors identify people at high risk of heart disease, leading to earlier prevention strategies

Read more: https://t.co/DhAqZJgZrT

[Donnelly Centre @DonnellyCentre]

Today, we're celebrating a two-decade milestone: on November 5th, 2005, we broke ground at the Donnelly Centre!

Thank you to everyone who has made Donnelly the building it is today!

[BHF Cardiovascular Epidemiology Unit at Cambridge @CAMBRIDGE_CEU]

🚨 Exciting new PhD Opportunity 🚨

Applications are open for 3-year non-clinical PhD studentships with the BHF Cambridge Centre of Research Excellence

📅 Apply by 23 Nov 2025
🌍 Open to UK & international applicants

Find out how to apply here: https://t.co/VcH6guSXrr

[Akl Fahed @aklfahed]

"This study demonstrates that PRS, when incorporated into existing risk prediction frameworks, are unlikely to meaningfully exacerbate disparities in CVD risk stratification."
https://t.co/78fKHIsDjj

[Sam Lambert @iamslambert]

Algorithmic fairness metrics are increasingly used in AI/ML to assess model bias. A clever PhD student (@claireicoffey) suggested applying these methods to clinical risk prediction or polygenic risk scores. See our new preprint for the whole story : https://t.co/nIbKrtJQko

[Sam Lambert @iamslambert]

@wilson_md @claireicoffey Thanks Mike! It feels like almost yesterday I was doing a PhD rotation with you… but maybe it’s been longer than that 🕰️

[Sam Lambert @iamslambert]

Congratulations @claireicoffey on passing your PhD viva (it's not everyday your first PhD student graduates)! It's been a pleasure to supervise your work applying algorithmic fairness techniques to risk prediction models and polygenic scores with Angela Wood & Mike Inouye.

[PGS Catalog @PGSCatalog]

📣 Thrilled to announce our collaborative tutorial with @EBItraining! Dive into the world of polygenic scores and explore the PGS Catalog resources (including pgsc_calc) - ideal for those seeking a comprehensive yet quick overview. Access it online at https://t.co/XbIODriufb!

[BHF Cardiovascular Epidemiology Unit at Cambridge @CAMBRIDGE_CEU]

From @sangerinstitute and the CEU!

Translating genetic changes into future health impact

New resource helps bridge the gap between identifying genetic changes linked to health conditions & understanding how these changes impact biological processes

🔗https://t.co/6HP1N0lA8R

[BHF Cardiovascular Epidemiology Unit at Cambridge @CAMBRIDGE_CEU]

New PhD studentship opportunities!

The Cambridge BHF CRE will be funding non-clinical 3-year PhD studentships, with a hope to recruit people interested in interdisciplinary projects

👉For more information & how to apply please visit https://t.co/O2gSiWzTtR
📅Apply by 16 Jan!

[Sam Lambert @iamslambert]

📢Fully-funded PhD studying the comorbidities of high adiposity. 🔗: https://t.co/8xPwG7eJZH (2 weeks left, due November 20)

Great work environment @CAMBRIDGE_CEU @HLRI_Cambridge, collab with @AstraZeneca @MikeXiao_JIANG @CambridgeATS.

DM or e-mail for informal enquiries.

[Sam Lambert @iamslambert]

Interested in a 4-year PhD studying the genetics of BMI and comorbidities? Don't wait, apply for my @AstraZeneca-funded studentship w/ @MikeXiao_JIANG 🔗: https://t.co/8xPwG7eJZH (due October 31)!

@CAMBRIDGE_CEU @HLRI_Cambridge @Cambridgecardio @DPHPC @CambridgeATS

[NHGRI-EBI GWAS Catalog @GWASCatalog]

HELP!

Which information would you like to see in @GWASCatalog regarding #ancestry?

📝 Fill out the survey (less than 1 min!)
https://t.co/8hgdiBC61Q
🗣️ Share with #gwas colleagues

#OpenAccess #Diversity #FAIRprinciples

[Sam Lambert @iamslambert]

@DrWillWatson @UHN I see you’re already hooked on Tim Hortons (which I controversially consider the Canadian equivalent to Greggs)!