Ian hoffecker

Molecular engineer & group leader at SciLifeLab & KTH Royal Institute of Technology. DNA nanotechnology, molecular programming.

[Ian hoffecker @ian_hoffecker]

Pleased to share our new preprint in sequencing-based microscopy and molecular networks, where we introduce spatial coherence - a deep connection between Euclidean geometry and spatially-informative networks. Congrats to David F. Bonet & other authors! https://t.co/krtYnfg1xp

[Ian hoffecker @ian_hoffecker]

Plug-and-play protein biosensors using aptamer-regulated in vitro transcription https://t.co/DtKMKmcZ5T nanotechnology

[Ian hoffecker @ian_hoffecker]

Controlled mechanochemical coupling of anti-junctions in DNA origami arrays https://t.co/cvmwpKFk9H nanotechnology

[Ian hoffecker @ian_hoffecker]

DNA microbeads for spatio-temporally controlled morphogen release within organoids https://t.co/eQZXZdi7tg nanotechnology

[Ian hoffecker @ian_hoffecker]

Single-molecule force spectroscopy of toehold-mediated strand displacement https://t.co/cG2MWbtnKO nanotechnology

[Ian hoffecker @ian_hoffecker]

A bioswitchable delivery system for microRNA therapeutics based on a tetrahedral DNA nanostructure https://t.co/vzf7UePq5U nanotechnology

[Ian hoffecker @ian_hoffecker]

DNA nanoswitches pack an anti-cancer punch https://t.co/t8DL2ReMij nanotechnology

[Ian hoffecker @ian_hoffecker]

Temporally controlled multistep division of DNA droplets for dynamic artificial cells https://t.co/LagPvdcI6P nanotechnology

[Ian hoffecker @ian_hoffecker]

DNA origami force probes illuminate T cell receptor forces at the immune synapse https://t.co/tlkEBZAKtw nanotechnology

[Ian hoffecker @ian_hoffecker]

Bottom-up synthetic immunology https://t.co/KoVABPtbSD nanotechnology

[Ian hoffecker @ian_hoffecker]

A lumen-tunable triangular DNA nanopore for molecular sensing and cross-membrane transport https://t.co/fvKb3xr8YQ nanotechnology

[Ian hoffecker @ian_hoffecker]

A primordial DNA store and compute engine https://t.co/E8UvHhogxc nanotechnology

[Ian hoffecker @ian_hoffecker]

Acoustically shaped DNA-programmable materials https://t.co/AprZ7aQ5ln nanotechnology

[Ian hoffecker @ian_hoffecker]

Neural coding of temperature with a DNA-based spiking chemical neuron https://t.co/3sQ41eUFKa nanotechnology

[Ian hoffecker @ian_hoffecker]

The unusual structural properties and potential biological relevance of switchback DNA https://t.co/8cLnEGnipr nanotechnology

[Ian hoffecker @ian_hoffecker]

Quantifying T cell receptor mechanics at membrane junctions using DNA origami tension sensors https://t.co/noupbSPe8q nanotechnology

[Ian hoffecker @ian_hoffecker]

Predicting the effect of binding molecules on the shape and mechanical properties of structured DNA assemblies https://t.co/FlWu89iGC0 nanotechnology

[Ian hoffecker @ian_hoffecker]

Co-transcriptional production of programmable RNA condensates and synthetic organelles https://t.co/QxIL4otL7b nanotechnology

[Ian hoffecker @ian_hoffecker]

Modular RNA motifs for orthogonal phase separated compartments https://t.co/tlAMwRtskh nanotechnology

[Ian hoffecker @ian_hoffecker]

A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway https://t.co/6eIAah363a nanotechnology

[Ian hoffecker @ian_hoffecker]

Morphologies of polymer chains spun onto solid substrates https://t.co/SeuX4vs8h4 nanotechnology