From ICEERS' Gabon interview series: Blandine Akendengue on iboga and the Nagoya Protocol, and on returning benefits to the communities who shared knowledge of the plant (French, English subtitles). #Gabon#Ethnobotany#Ibogaine
Preclinical: a Dalhousie-led study in the European Journal of Pharmacology proposes that ibogaine acts through metabolic preconditioning in mouse neurons. Early mechanism work, not clinical evidence. #Neuroscience#Ibogaine
At a federal panel, FDA, VA and ARPA-H officials discussed psychedelic access: VA has picked 10 sites, and psychedelics now make up about a third of FDA psychiatry's workload, Psychedelic Alpha reports. #PTSD#FDA#Ibogaine
Gabon's iboga value chain: clinic fees abroad reach up to 17.5M CFA per patient, while one local association earned just over 32M CFA from three legal shipments, Financial Congo reports. A temporary export ban remains. #Gabon#Conservation#Ibogaine
KXAN (Apr 2026) on what's next for Texas's state-funded ibogaine research after the program hit a road bump finding a drug-company partner. Background as FDA takes comment on trial design through Nov 20. #Ibogaine#ClinicalTrials#DrugPolicy
FDA is taking public comment on early-phase ibogaine trial design, including a starting dose no higher than 10 mg/kg. CDER's Michael Davis cites "serious safety concerns" and open scientific questions. Comments close Nov 20. https://t.co/mJlgT4rfEM #FDA#ClinicalTrials#Ibogaine
Denver Health's Dale Terasaki, MD, on his Journal of Addiction Medicine commentary on ibogaine for opioid use disorder, and why buprenorphine and methadone remain central as research proceeds. https://t.co/QvZpwFEpR7 #Ibogaine#OpioidCrisis#AddictionRecovery
Gabon's Decree 0239 (May 2026) requires authorization and benefit-sharing for commercial use of iboga and associated traditional knowledge; a Sept 18 draft decree would halt exports. The Guardian on the debate: https://t.co/14fdiCefa8 #Gabon#Iboga#Bwiti
Psychedelic Alpha (Oct 21) publishes an interview with HHS Deputy General Counsel Matt Zorn on ibogaine, Right to Try and the April psychedelics executive order. Ibogaine remains Schedule I in the US. https://t.co/Ib5UQtqDOY #DrugPolicy#Ibogaine
Pink Sheet's Drug Fix podcast (Oct 9) walks through FDA's request for information on ibogaine trial design: inpatient cardiac monitoring, the 1990s safety history, and the hurdles for sponsors. https://t.co/3wFvHrmLZT #Ibogaine#FDA#ClinicalTrials
Texas HHSC's ibogaine trials page still says plans submitted so far don't meet state requirements on matching funds and IP revenue; no consortium contract is listed yet. Ibogaine remains Schedule I in the US. https://t.co/xhl8nFR4vf #ClinicalTrials#DrugPolicy
> Psychedelic Alpha (Oct 20) recaps FDA's draft blueprint for early ibogaine trials: CYP2D6 genotyping, pausing certain medications, five stopping rules and 12 months of cognitive follow-up. Not final. https://t.co/mo3xCquOX0 #PsychedelicResearch#ClinicalTrials
FDA's ibogaine trial-design docket (FDA-2026-N-10429) has 24 public comments as of today. The RFI floats single-dose ascending cohorts capped at 10 mg/kg and inpatient cardiac monitoring for up to ~36 h. Comments close Nov 20. https://t.co/QHMYSPpPPL #FDA#ClinicalTrials
KXAN (April): Texas set aside $50M for ibogaine clinical trials. Texas HHSC now says the plans submitted so far don't meet state requirements on matching funds and IP revenue. Ibogaine remains Schedule I in the US. https://t.co/Br8pEzasnq #ClinicalTrials#MentalHealth
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The Guardian (Oct 18): Gabon's former environment minister calls wild iboga "rare and poorly studied," and park patrols found severe local over-harvesting. A Sept 18 draft decree bars export of iboga and its derivatives. https://t.co/14fdiCefa8 #Gabon
Stanford (Oct 12): in a one-year follow-up of 30 special-ops veterans with TBI given ibogaine plus magnesium in Mexico, most early PTSD remissions held at 12 months. Observational study; many later had other treatments. https://t.co/F7Xq7RTsWM #MentalHealth#PTSD#Ibogaine