Hiroshi Ichise

[Waggoner Lab @LabWaggoner]

Preprint: A Skin–Lung Vagal Reflex Regulates Airway Inflammation
https://t.co/6nElHNDXQZ @itchdoctor @rofu47 @IcahnMountSinai

[Hiroshi Ichise @IchiseH]

@immunologyliz @Nature @wenzhang1120 Huge congratulations!!

[Hiroshi Ichise @IchiseH]

@wenzhang1120 @Nature Huge congratulations!!

[Wen Zhang @wenzhang1120]

I’m thrilled to share our new @Nature study revealing a previously unrecognized neuro–epithelial circuit that actively regulates intestinal type 2 immunity. If you’re interested in sensory neurons, chemosensory tuft cells and type 2 immunity, this one’s for you. (1/6)

[Elizabeth Emanuel @immunologyliz]

Extremely excited to share my first first-author publication posted today in @nature, a joint effort with co-first author @wenzhang1120 !

Here, we identify a novel neuronal-epithelial circuit as a critical determinant of type 2 immunity.

https://t.co/fsuhWiSIZV

[Cancer Cell @Cancer_Cell]

Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses https://t.co/NO9VtBbfmt

[Science Magazine @ScienceMagazine]

Recovery from deadly influenza infection may hinge on helping the lungs heal in addition to stopping the virus, according to a new Science study in mice.

The results show that pairing modest antiviral therapies with immune modulation can restore damaged tissues and lung function, even after severe infection has taken hold. https://t.co/WnkwiaAm5P

[David Usharauli @3DiMMUNE]

A new study from the Germain lab delivers a stark reality. In a lethal flu mouse model testing 50 regimens, only Tamiflu alone or with IFN I blockade or CD8 depletion improved survival.

#science
#Immunology

https://t.co/YvpEHulNjs

[Hiroshi Ichise @IchiseH]

Beautiful work!

Inhibitory PD-1 axis maintains high-avidity stem-like CD8+ T cells

https://t.co/91pbCKvv06

[Cell @CellCellPress]

Now online! Properties and functions of transcriptionally distinct enteric neurons https://t.co/VHw85IiT3q

[Cell @CellCellPress]

Now online! IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness https://t.co/EN8WTBWdZX

[Hiroshi Ichise @IchiseH]

I am thrilled to share one of my new research entitled “Rebalancing viral and immune damage versus repair prevents death from lethal influenza infection” now on Science! https://t.co/Fq9EAXrGyX.

[Andrew Akbashev @Andrew_Akbashev]

Pressure to publish jumps. And researchers have no time to do science.
(New survey from Elsevier)

Survey of 3200 researchers:

1. Only 45% of scientists have sufficient time for actual research.

2. For 68%, the pressure to publish today is greater than 2-3 years ago.

3. 29% of researchers are considering relocating to another country (for better funding, work‐life balance, or greater research freedom).

4. 58% of researchers use AI tools in their work.

5. Reported benefits from AI: saving time (58%), helping with literature summaries (61%), literature reviews (51%), data analysis (38%), drafting proposals (41%), and drafting papers (38%).

Globally, life in academia is getting worse.

For students & postdocs - it’s especially hard to decide on an academic career.

❗️ A few days ago, I gave a lecture on this topic.

“PhD: Dreams, Reality and Consequences”

Watch it here: https://t.co/5IFhcVFwIL

(I’ll appreciate if you ‘like’ this video - you will GREATLY help it reach more students.)

[Waggoner Lab @LabWaggoner]

A vasculature-resident ILC3 population in mouse lungs that expands during Pseudomonas aeruginosa infection & produces CCL4 to recruit neutrophils for bacterial clearance
https://t.co/qVbIWHkpXx

[Hiroshi Ichise @IchiseH]

Spatial Patterning Analysis of Cellular Ensembles (SPACE) finds complex spatial organization at the cell and tissue levels | PNAS https://t.co/7eOp1RveQ9

[Nature Methods @naturemethods]

The wait is over!! We are thrilled to announce that we have chosen Spatial Proteomics as 2024’s Method of the Year! 🥳

For more on Spatial Proteomics and a road map to this special issue, please see this month’s Editorial or read on in this thread.

https://t.co/phXooJzJda

[nature @Nature]

The huge toll of PhDs on mental health: data reveal stark effects https://t.co/7GIeZOf14c

[Guolan Lu @GuolanLu]

Please RT. I am currently hiring graduate students and postdoc fellows. Details can be found here: https://t.co/eU2Xk0g07u My lab is dedicated to developing and integrating imaging, AI, and spatial omics technologies to uncover mechanisms driving disease initiation, progression, and therapeutic response, with the ultimate goal of advancing next-generation theragnostics to cure diseases. We are excited to be equipped with cutting-edge spatial omics technologies, including Xenium spatial transcriptomics @10xGenomics and Phenocycler-fusion @AkoyaBio .

[bioRxiv Immunology @biorxiv_immuno]

Rebalancing Viral and Immune Damage versus Tissue Repair Prevents Death from Lethal Influenza Infection https://t.co/Oogi1Z1DEr #biorxiv_immuno