Doug

Traveling the west coast of North America (or not, during SARS-CoV2 lockdown) on my sailboat. Currently in El Salvador. Mostly political ramblings right now.

[Doug @Illusion]

Important research to help modern medicine's arsenal mitigating human disease onslaught. https://t.co/1vTIC3jfmq

[Doug @Illusion]

@BrianLehrer @DrKBrandi @VickieforNYC @EricHolder @SammyKoppelman @WNYC Msging from El Salvador right now: abortion is illegal here, where women have spent years in prison for miscarriages. Hope that doesn't happen in USA, but likely will.

[Eric Topol @EricTopol]

Just published @NEJM
Neutralizing antibody levels and T cells response out to 8 months for Pfizer, Moderna and J&J vaccines
https://t.co/ghAgk3Y4kR
Moderna highest antibody response; J&J while lower doesn't fall off and best CD8 T-cell response at 8 months

[Doug @Illusion]

@helenleigh Pass the Stilton, please

[Doug @Illusion]

@brianlinworks @MissedinHistory @EurekAlert This makes me sad, in an era of so much misinformation, that such a bright beacon for science info has gone dark. Can anyone address directly why EurekAlert removed RSS feeds? It was clearly a conscious decision, but I've not seen it illuminated within the "reimagining" paradigm.

[Eric Topol @EricTopol]

Delta D, a sub-lineage or clade that has evolved from Delta (B.1.617.2), has unclear functional significance (vs Delta), and is now accounting for most cases throughout the world
https://t.co/06pokfdKKy and https://t.co/zQ0yZBfj9R

[Doug @Illusion]

@RightangledLtd Scammed, too. Also bought Day-5 test, thinking processing times would make it useful (like all NHS tests I've done for travel). I wish I could have just sent my money to the @NHSuk - at least I know they've got their act together for COVID testing.

@BBCPanorama @PHE_uk HELP US!

[Eric Topol @EricTopol]

Just published @NatureMedicine
Mix and match AZ (vector) vaccine: Adding mRNA (as 2nd dose) led to a better immune response than 2 AZ doses and CD8+ T cells was even better than 2 mRNA doses. And well tolerated
Prior tweet deleted (not J&J), sorry, too early in the morning here

[Doug @Illusion]

Anyone who wants to hear detailed rebuttal of the wild SARS-CoV-2 origin stories going around, definitely worth a listen/watch. Even if you don't understand the detail, there's a lot to help relieve one's concerns. The whole podcast series is amazing!

[MicrobeTV @profvrr]

Robert Garry joins #TWiV to explain how the molecular biology of #SARSCoV2 shows that it came from Nature and not a lab, including the receptor binding domain, the furin cleavage site, and the two lineages circulating in Wuhan wildlife markets https://t.co/LSdkUFKeGp

[Doug @Illusion]

@TenAmorette One is slightly red where it counts. 😅

[Daniel Griffin MD PhD @DanielGriffinMD]

COVID Stage Paper now accepted for publication in so will post link to paper when available but here are the 'polished' figures. The reason I like peer review is despite the pain I do think it improves the final product. Thanks to all the reviewers :-)

[Doug @Illusion]

@andrewhorowitz I am an expat American, currently in the UK, but spent most of the pandemic in Latin America. Probs here are due to poor prep: inadequate guidance, test availability, tracking, etc. Not too different from happenings in the US, but not JUST for US consumption. Sad, regardless.

[Doug @Illusion]

I learned about this idea from @michaelmina_lab on This Week in Virology #640 in mid-July. I've been working on my own video (&taking care of a 5yo!) since then - not ready yet since 5yo w/Playmobil demand more attn. But this is prob the most important idea in COVID-19 times!

[Michael Mina @michaelmina_lab]

Are we quarantining millions of people unnecessarily?

Article by @apoorva_nyc on pitfalls of #COVID19 PCR for quarantine / public heatlth action / policy.

*Disclaimer* the article is based on my discussions with her.

I want to clarify here:

1/17

https://t.co/XXd7lCYp5M

[Ben Hunt @EpsilonTheory]

Facebook is a profound and direct threat to liberal democracy. The company should be razed, and the ground sown with salt.

https://t.co/4cVk1IqDp0

[Dr. Eddie Ramirez @EddieRDMD]

NEJM: Investigators report that saliva specimens and nasopharyngeal swab specimens had similar sensitivity in the detection of SARS-CoV-2 RNA in both symptomatic and asymptomatic persons. https://t.co/ziRTSCAKoW @_atanas_

[Eric Topol @EricTopol]

"The economic value of a face mask is $56.14"
😷 crossover, inter-dependent benefit, quantified
"A 15%-point rise in the share of the population that wears masks would ⬇️ the daily growth of cases by about 1 percentage point"
https://t.co/vEC9FGopAY @TheEconomist @GoldmanSachs

[Eric Topol @EricTopol]

This doesn't seem good
https://t.co/GclNrdIQrp (print version of below)

[Duty To Warn 🔉 @duty2warn]

Hilarious satire by George Conway using Trump’s own words. If you believe everything Trump has said, as he purports to do, it sounds insane https://t.co/2fhC9MWnpm

[Elizabeth Warren @SenWarren]

There is nothing normal about a Trump campaign megadonor with at least $30 million invested in @USPS competitors being appointed as Postmaster General to sabotage our mail delivery & threaten our elections. The @OIGUSPS must investigate this corruption now.https://t.co/iQEx4Nym5W