I just updated my notes on "Soft tissue tumors" for my teaching website, "Kurt's Notes" (https://t.co/OKmaPvGQpJ).
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Full notes available here: https://t.co/uWZ1UdMRV8
Happy New Year to everyone! First case of 2026.
Female in her 50s. Multiple mixed sclerotic and lytic lesions involving the thoracic spine and pelvis.
#PathX#PathTwitter#BSTPath
Microglandular adenosis
This is the only benign breast lesion that lacks a surrounding myoepithelial layer.
The glands are S100-positive and have an intact basement membrane (demonstrated by IHC or reticulin stain, which highlights the basement membrane).
Dr. Wen - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX
59 year-old with diarrhea undergoes colonoscopy.
What is the diagnosis?
A) Lymphangiectasia
B) Juvenile Polyposis
C) Ménétrier’s Disease
D) Cronkhite-Canada
https://t.co/P4Y3L3gw4T
#GIPath#PathTwitter#Pathology
Exploring the comprehensive WHO classification of thyroid tumors from the 5th edition!
🔬This detailed chart breaks down the cellular origin, genetic classification, and histological features of various thyroid neoplasms
Reference: https://t.co/y3iurxi1PC
Sarcoma 101 - Bone & Soft Tissue Tumor Classification/Names Made Simple video: https://t.co/9OwCAOEWrK . My 2021 lecture for NCI SEER cancer registrars. Also good for #medstudents, jr. #pathologists, ortho/oncology, & patients/family. #medtwitter#pathology#orthotwitter
Lung. Diagnosis?
A) Atypical Adenomatous Hyperplasia
B) Adenocarcinoma in situ
C) Minimally Invasive Adenocarcinoma
#pulmpath#pathtwitter#pathresidents
⚠️SA involved by LCIS/DCIS can be mistaken for invasive carcinoma⚠️
Features suggestive of SA:
🔑 myoepithelial cells on IHC (⚠️reminder: E-cad IHC stains myoeps)
🔑 lobulocentric architecture
🔑 dense rather than desmoplastic stroma
🔑 identifying SA in adjacent breast helpful
Recent case. Young female patient with 70 mm unilateral adrenal mass. Hormonal workup is negative. Suspected mets to liver and lung. Core needle biopsy of liver mass. Some teaching points are provided below: