Simon Roy MD

Dermatopathologist I McGill Melanoma Research | Climbing, sourdough baking 👨‍🍳 Own views

[Simon Roy MD @SimonRoyMD]

1/ 🚨 Excited to share our latest publication in Pathology! We explored the role of tumour necrosis as a prognostic factor in vulvar and vaginal melanomas (VVMs) and recommend that this be reported in synoptic surgical pathology templates to help refine staging.

[Hunter Shain @ShainLab]

Proud to share our new paper in Science Advances.

We show that indoor tanning causes widespread mutational damage across the skin to increase melanoma risk, especially in body sites that rarely see sunlight.

https://t.co/OtBMOEGh29

#Melanoma #SkinCancer #CancerResearch

[Simon Roy MD @SimonRoyMD]

@HENRYY_MD Neat, thanks Henry!

[Daniela Robles @daniela-oaks.bsky.social @daniela_oaks]

I am really happy to see the #preprint of our work studying #acral #melanoma tumours from 🇲🇽 Mexican patients out today! This has been a ~8 year-long work involving many colleagues from Mexico and abroad. Some of our findings here below.... ⬇️ (1/12)

[Daniela Robles @daniela-oaks.bsky.social @daniela_oaks]

The next speaker in the #Mexico, #Central and #South #America research session is by @PatriciaPossik 🇧🇷, and she is telling us about the genetic landscape of #acral #melanoma in Brazilian patients @PASPCR1

[Daniela Robles @daniela-oaks.bsky.social @daniela_oaks]

An honour to listen to Ruth Halaban @Yale, the first woman that graduated from @Princeton with a PhD degree in biology and recipient of the @PASPCR1 lifetime achievement award, talk about the #LZTR1 gene and #melanoma

[Simon Roy MD @SimonRoyMD]

*I added morphology descriptions if you click on “ALT” on the bottom left of the pics.

[Simon Roy MD @SimonRoyMD]

WNT-activated melanocytoma with background melanocytic nevus. You don't always get such a good beta-catenin staining, got lucky over here. These often are concerning clinically due to the heterogenous pigmentation. #dermpath

[Robert Avram @RobertAvramMD]

FRESH OFF THE PRESS - New study in @escardio @ESC_Journals Prediction of incident atrial fibrillation using deep learning, clinical models and polygenic scores shows #AI can predict new-onset atrial fibrillation from ECGs with high accuracy, outperforming clinical and genetic risk scores. #ESC2024 #ESCCongress

https://t.co/bUKayTyCKz

📌 Bookmark, reshare, and read this thread! We're taking you on a journey of our main findings BELOW #OpenScience 🧵👇

[Tristan Rutland MBBS FRCPA IFCAP @TristanRutland7]

Lower leg, Male

#Dermpath #IDpath #Pathtwitter

[Simon Roy MD @SimonRoyMD]

@whitefishlab @GSKGradSchool @SarahPerlee Congrats Sarah!

[Melanie Bourgeau, MD @MELanocyteMD]

68♂️ w/ lytic femur mass

Is it...
1️⃣ Sarcoma?
2️⃣ Melanoma?
3️⃣ Carcinoma?
4️⃣ Lymphoma?

🔎WSI: https://t.co/yRWzPoBIoH
�� Answer: https://t.co/DYopSOSZWe

#BSTpath (...or is it? 🤔)

[Goran Micevic MD/PhD @gmicevic]

@ElizSMcKenna We study epigenetics in cancer immunology at #Yale and we are hiring: https://t.co/UET1MJK9fp #newPI

[Simon Roy MD @SimonRoyMD]

Chondrodermatitis nodularis helicis! You don't always see the "textbook" cartilage alterations. #dermpath

[Simon Roy MD @SimonRoyMD]

@RACARR51 Tumoral melanosis?

[Simon Roy MD @SimonRoyMD]

@RACARR51 Thanks for sharing Richard! I’ve been using your algorithm the past 6 months or so and have been finding it super useful.

[Simon Roy MD @SimonRoyMD]

@HENRYY_MD @EssaoudiMohamed @kis_lorand @DrGeeONE @JacobSmalberger @RACARR51 @tonitatirado @gonzadetoro @david_terrano @et565 @Dr_Jukic @ASDPTweets @mccalmo @MarcelaSaebL @HoustonArsenal Thanks for sharing! My amazing mentor @JenniferMcniff has a great paper about the use of CD34 for cellular digital fibroma. 14/14 were +. https://t.co/mdfjhkFN8o

[Simon Roy MD @SimonRoyMD]

@ShainLab Congrats Hunter and team!

[Nature Communications @NatureComms]

.@MengWang55 @ShainLab @IweiYeh @Ishanibanik1 @UCSF @UCSFCancer sequence #AcralMelanoma at different stages, find punctuated clusters of copy number alterations and specific driver mutation timing
#CancerResearch @NatResCancer https://t.co/fs26OUHFnZ