International Society of Urological Pathology

Creating global urological pathology guidelines and educational initiatives. Official Companion Society of @TheUSCAP. 🔬 Managed by @katcollmd

[International Society of Urological Pathology @IntSocUropath]

🚨 ISUP Presents.....

🔬 Dr. Bogdan Czerniak on “The Mystery of Cancer Initiation:
Lessons from Bladder Carcinogenesis”

📅 24 June 2026 at 1pm EST via Zoom

Register here: https://t.co/HWquwSiPXQ

[Springer Pathology @SpringerPath]

A study in Virchows Archiv examines the role of FOXL2 as an immunohistochemical marker in identifying ovotesticular cords in pediatric patients with ovotesticular disorders of sex development. Findings support its diagnostic utility.

https://t.co/Vhtk86gPk6

[Lorand Kis @kis_lorand]

Thightly packed glands of acinar prostatic adenocarcinoma mimicking cribriform GG4...the way to tell them apart is to look at high magnification and find/exclude the surounding stroma/collagen bundles (marked with green in the last picture)
#pathology #GUpath

[Sounak Gupta @Shounak_Gupta]

The MiT/TFE family of transcription factors comprises MITF, TFE3, TFEB, and TFEC.

MITF/ TFE3/ TFEB-altered RCC have been reported.

Possibly, the first report of TFEC-rearranged RCC (@Human_Pathology)?

https://t.co/ujjtMkgbaF

[International Society of Urological Pathology @IntSocUropath]

Go to https://t.co/FGDgH231q4 to see more of the case! #gupath #pathtwitter #ISUPCOTM

Authors: Ting Zhao, MD, Kyle M. Devins, MD; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA @TingZhaoPathdoc @md_kyle

[Histopathology @Histo_Journal]

An in-depth discussion of the challenges that pathologists may encounter when grading clear cell renal cell carcinoma and papillary renal cell carcinoma, with a focus on the WHO/ISUP grading system and attention to recent updates. #gupath @GladellPaner https://t.co/rD7Ok8rp0n

[International Society of Urological Pathology @IntSocUropath]

🚨 ISUP Presents.....

🔬 Dr. Bogdan Czerniak on “The Mystery of Cancer Initiation:
Lessons from Bladder Carcinogenesis”

📅 24 June 2026 at 1pm EST via Zoom

Register here: https://t.co/HWquwSiPXQ

[Michelle_Hirsch (Donovan) @MichelleDunno17]

Now in press in Virchows Archiv-->Multi-institutional cohort of 18 renal tumors, uniquely ALL with proven FLCN biallelic inactivation -> morphology, molecular, IHC, and clinical follow-up.🔬
@ESP_Pathology @GU_Path_Society @IntSocUropath
#kidneycancer
#BHD #birthoggdube #gupath

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬

A) High-grade prostatic intraepithelial neoplasia
B) Intraductal Carcinoma of the Prostate
C) Conventional Acinar Adenocarcinoma
D) Prostatic Ductal Adenocarcinoma

#Pathology #GUPath 🧬 #ProstatePath

[Guan-Nan Zhang ，张冠楠，MD, PhD @GuannanTiffany]

🧩 Bladder riddle

When urothelial carcinoma decides to go wild before conventional invasion pattern (Desmoplasia ; Retraction artifact ; Complex architecture ;Paradoxical differentiation) 

What would be your diagnosis?

#DxMindMap #GUPath #BladderPath #PathTwitter @JHUpath

[Ahmed Montasser @AMontasserMD]

S E M I N O M A

#Pathology #GUpath #PathTwitter #PathX #Classic 🔬

[Ankur Sangoi @slusagar]

#GUpath #endopath cystic adrenal mass

🔬adrenal endothelial cyst

⏬cont'd⏬

[sena naz 🍉 @senaadsizdayanc]

Chromophobe renal cell carcinoma 🧚🏻‍♀️
#gupath
#kidneytumor
#pathology

[Int J Surg Pathol @IJSPjournal]

#Hemepath meets #GUPath
Pitfall alert 🚨GATA3/p63➕ in urinary bladder lymphomas (some with colonization of overlying urothelium) may mimic urothelial carcinoma (in situ)
Weird bladder tumor? Consider doing a keratin!
👉🏼IJSP read of the day: https://t.co/hlRjemsQ1h
#PathTwitter

[Everyday_Pathology @Pathology_Xever]

Uropathology webinar https://t.co/ImgkCx0SBF

[Liang Cheng, MD @LiangChengMD]

How to grade prostate cancer in small biopsy specimens remains one of the most challenging and controversial areas in daily urologic pathology practice.

This recent review article published in Urologic Clinics of North America,
“Prostate Cancer Grading: An Update,” by Drs. John Hanna, Gennady Bratslavsky, Jeffrey S. Ross, Oleksandr Kravtsov, provides an excellent practical overview of many real-world diagnostic dilemmas encountered in prostate biopsy interpretation.

The review discusses contemporary Gleason grading, Grade Groups, quantification of Gleason pattern 4, cribriform morphology, intraductal carcinoma, grading pitfalls in minute tumor foci, interobserver variability, and emerging AI applications in prostate pathology.
Article link: https://t.co/rs5EwjMDkF

[Swati Bhardwaj, MD @DrSwatiBhardwaj]

Excited to share our paper published in @Human_Pathology!
Incredibly grateful to my mentor, Dr. Tamara Lotan @LotanLab, for her guidance, mentorship, support, & encouragement and collaborators & co-authors
@Williamson_SR @PeterArgani @AsraniKaushal
@JHUPath
Read it here: https://t.co/sO199eeLnC

[Guan-Nan Zhang ，张冠楠，MD, PhD @GuannanTiffany]

🧩 Bladder riddle

Inspired by the previous post…

Here is another spindle cell neoplasm. 🤔

Bland-looking spindle cells with eosinophilic cytoplasm, oval nuclei, and small round nucleoli.

What would be your diagnosis?

#DxMindMap #GUPath #BladderPath #PathTwitter @JHUpath

[Ankur Sangoi @slusagar]

#GUpath bladder

⏬cont'd⏬

[Samson W. Fine, MD @rovingatuscap]

'Feelin' Groovy' - florid urothelial metaplasia in a prostate needle biopsy, mimicking basal cell hyperplasia and HGPIN at low magnification; at high magnification cytoplasmic vacuoles (upper R) & nuclear grooves (lower R) in the metaplastic cells aid in identification #gupath

[Springer Pathology @SpringerPath]

Research identifies a high-grade renal cell carcinoma with a somatic BRCA2 mutation, showcasing unique histological patterns. This case reinforces shared features among previously reported cases, suggesting a distinct subtype of RCC.

https://t.co/YQSURgMZry