Excellent work! ✨
✅ Classic Adenoid Cystic Carcinoma
A biphasic epithelial-myoepithelial neoplasm arranged in cribriform and tubular structures with basement membrane-like material, associated with MYB::NFIB fusion and an excellent prognosis.
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Join us on #pathCast#GIPATH for a focused look at key updates from the WHO 6th Edition Classification of Digestive System Tumors with @RaulSGonzalezMD
🗓️ May 26, 2026
🕛 12 PM EST
🔴 LIVE on Facebook + YouTube / @pathCast
🌐 https://t.co/YuEvyboogA
#Pathology#WHOTumors
Gorgeous complex sclerosing lesion (CSL) with pseudoinfiltrative central tubules AND a sneaky unwelcome visitor.
Brings to mind the adage about the two kinds of pathologists: those who have missed invasive lobular carcinoma, and those who will 😅
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When large nests of tumor surround a completely normal duct, they are much more likely to be invasive cancer or lymphovascular invasion than DCIS. A useful pattern to remember on a biopsy
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Brave New World of Breast Pathology 🧑🏫
We’ll discuss breast tumors defined by recurrent alterations—how to recognize them on H&E and triage ancillary testing, including Pan-TRK 👇.
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Uh oh! Perineural invasion (PNI) is not reported in breast.
Unlike other organs, PNI in breast has inconsistent evidence for prognostic significance and limited impact on management. Current data do not support routine standardized reporting.
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Cervix - Multifocal invasive tumors
- FIGO 2018 does not require horizontal extent for microscopic, superficial (microinvasive) tumors.
- Stage is based on greatest depth of invasion (DOI).
- Do not add tumors to calculate tumor size.
Dr. Park - Daily challenges in cervical cancer reporting
Case of Atypical Ductal Hyperplasia (ADH) in Mucocele-Like Lesion 🍪🔬
☑️ Dilated ducts with extravasated mucin
☑️ Foci of ADH lining mucin-filled spaces
☑️ Upgrade rate to DCIS/invasive carcinoma is 20-40%
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