The Clinical and Cognitive Neuroscience Center is a research laboratory focused on understanding the neural mechanisms of psychosis, ASD, and cannabis use.
Inpatient psychiatric care often overlooks psychosocial drivers of crisis. Our recent JAMA Psychiatry Viewpoint outlines why fully integrating psychologists into inpatient teams is not only feasible—it’s evidence-based and overdue. https://t.co/578ce4gDoH
RCT: For people with schizophrenia-spectrum disorders and persecutory delusions, psychotherapy reduced how much volatility the individual expected in their environment. https://t.co/QMf8Fg6pO0
New from CCNC PI Alexandra Moussa-Tooks, @hbwardMD & colleagues! "Grip Strength as a Marker of Resting-State Network Integrity and Well-Being in Early Psychosis." @APApsychiatric
Grip Strength Reveals Brain Clues Behind Early Psychosis
Psychosis may begin with something as simple as a weak grip.
Researchers have found that individuals in the early stages of psychosis tend to have reduced grip strength, which correlates with decreased connectivity in brain regions tied to both motor skills and mental well-being.
These regions—such as the anterior cingulate cortex, sensorimotor cortex, and cerebellum—show disrupted connections with the brain’s default mode network.
This pattern of dysfunction may underlie the broader symptoms of psychosis.
The findings suggest motor function could serve as an accessible early marker for brain disturbance.
It also highlights grip strength as a potential tool for diagnosis and intervention.
It was a blast to watch the CCNC get represented in The Candy Stripe Classic Race by our very own Chloe Eades. She got 2nd in her division and fourth overall! #CCNCoutsideofthelab
Had a great time @srp_science in Montréal presenting research (incl. on interoception, affective self-perception, social networks, perinatal factors, facial affect processing) and seeing old and new friends (>3 generations of CCNC members!).
Congrats to CCNC undergrad @ChloeEades for her published blog post @ScIUBlog. Chloe examined how the movie “Perks of Being a Wallflower” depicts a diagnosis of PTSD within the main character. Read it here 👇https://t.co/4og1b9B41z
Congrats to CCNC undergraduate @ChloeEades on being awarded an IU Hutton Honors Summer Research grant! Chloe will be studying the relationship between motor learning and changes in negative symptom traits associated with psychosis in young adults @IUPsychBrain
We are so excited to congratulate IU senior in the lab, Jake Isenman, on completing his Honors Thesis @IUPsychBrain!
He worked with grad student @wolny_j and Dr. Alex Moussa-Tooks to investigate the role of major discrimination and microaggressions on paranoia.
New from CCNC PI Dr. Alex Moussa-Tooks @IUPsychBrain and Dr.@hbwardMD/@VUMCPsych! They identify distinct cerebellar circuits driving action and cognition subprocesses of psychomotor function in individuals with and without a schizophrenia-spectrum disorder https://t.co/OSCOUkRHm4
Exciting findings from the CCNC! Our latest paper by @wolny_j, in collaboration with @Temple_Psych and @UMNPsych, delves into the equitable measurement of paranoia across diverse populations. To learn more about group comparisons, check out our paper here: https://t.co/S0AleN5Z69
Happy to share our review on threat responses in schizophrenia!
@JenniBlackford @NeilWoodward20 @StephanHeckers@VUMCPsych@iubccnc
https://t.co/ChtqHKhNnr
Now out in @SchizRes: Work from Lauren Hall, including @IUPsychBrain alum Drs. Alex Moussa-Tooks and Allen Bailey and @jmsheff @VUMChealth continues to disentangle how psychopathology measures may be biased by racial and cultural differences. Read here: https://t.co/53mpTpvnpT
Very excited to share this commentary with twitterless Alex Moussa-Tooks @iubccnc on practical strategies for ⭐️mentors⭐️ to improve retention of underrepresented minority trainees in science and medicine just published in @ACNPorg@VUMCpsych 🧵 https://t.co/mCapQVNJVo
Very happy to share the first publication with my fantastic (albeit Twitterless) PhD advisor Krista Wisner and colleagues at Indiana University. @iubccnc
Our department is hiring!
-Tenure-Track Faculty Position at Indiana University Bloomington.
-Topic area and rank are completely open!
We look forward to growing our faculty in new and exciting ways. Please share widely :)
https://t.co/pn0AADVLse
At Saturday’s poster session, @wolny_j will present “Race and Self-Reported Paranoia: A Contextualized Item-Level Analysis of Psychosis-Spectrum Symptoms”