Ivan Mindlin

Finishing PhD candidate at Paris Brain Institute.
Now in BlueSky:

[Ivan Mindlin @ivan_mindlin]

Taking the momentum of our new-fresh-out-of-the-oven pre-print to fully move to BlueSky.

Check the post to check the work: https://t.co/dgdViWk5HI

See you there :)

[Ivan Mindlin @ivan_mindlin]

Registration is open until April 25. No abstract is needed, but we encourage to submit (even with preliminary work 😉)

More info at https://t.co/A7N94SQlg9

Registration HERE:
https://t.co/3jjcCQIVPz

Hope to see you there ☀️

[Ivan Mindlin @ivan_mindlin]

📢 Registration extension📢

Join us in the Embracing Complexity Workshop: Principled and Practical Approaches to Emergence!

The workshop is scheduled for June 23-27 2025 at the Institute for Cross-Disciplinary Physics and Complex Systems in Palma de Mallorca, Spain 🇪🇸

👇👇👇

[Ivan Mindlin @ivan_mindlin]

@anton_pashkov03 Hi Anton! No, it’s made by modifying s in eq (5). This is the parameter that we shift :)

[Ivan Mindlin @ivan_mindlin]

📢Paper out📢
“Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness”
https://t.co/qYaxvjGauz
👇Brief summary below👇 (1/8)

[Ivan Mindlin @ivan_mindlin]

Many thanks to @jdsitt and @ysanz6 for your supervision🧠, @ETagliazucchi and all the coauthors for the ideas and discussion 💪

[Ivan Mindlin @ivan_mindlin]

In conclusion, our in-silico representation of patients hints that healthy-like brain dynamics might be recovered from DoC models through pharmacological perturbations, especially via serotonergic and opioid receptors, offering mechanistic insights into their effects. (8/8)

[Ivan Mindlin @ivan_mindlin]

Thank you @ysanz6 and @jdsitt for your supervision 🧠and @ETagliazucch and the rest of the co-authors for their contribution 🦾

[Ivan Mindlin @ivan_mindlin]

Interestingly, these shifts did not correlate with the receptor's similarity to structural connectivity but with the overall density of the receptor map. 5HT-2A receptors were more sensitive to perturbations. (7/8)

[Ivan Mindlin @ivan_mindlin]

Many many thanks to the team and to @ysanz6 and @jdsitt for their guidance in this project 😁

[Ivan Mindlin @ivan_mindlin]

🚨First PhD preprint 🚨Here we propose a methodology for pharmacological treatment development of DoC. Our model suggests that high density receptors like 5HT2A and 5HT1A are the optimal to recuperate healthy-like dynamics in a DoC model.
https://t.co/i6WBRzg5lV