New: #LongCovid patients have alterations to the choroid plexus and reduced cerebral blood flow.
The alterations were associated with Alzheimer's markers, including GFAP and p-tau217.
https://t.co/qv9klVg7kI 1/
Happy to share that after a prolonged peer-review process, our review covering the major Neuroinflammatory events in #LongCovid was accepted today for publication at @Transl_Psych from the @NaturePortfolio! Coming soon, but preprint available here: https://t.co/Pa1ME9eRpT
What am I seeing?
- Reduced empathy
- Increased aggression
- Rising support for authoritarianism
- Declining critical thinking
- Less moral inhibition
- Rising disinhibition & antisocial behavior
- Lack of focus/commitment
- Frequent memory lapses
- Increased impulsivity
New study that once again shows #LongCovid recovery is very rare:
"Among participants followed up to 3 years after initial infection.. The majority of those with Long COVID did not resolve, with less than 2% having resolved Long COVID."
https://t.co/HKGSeVZRFD
@reality19713@CatchTheBaby No it is not. It is very common.
https://t.co/RnD7JeXc3g
This is babies 0-5
https://t.co/k6RyD3Lxr6
Wider scoop children all ages
https://t.co/TLcqKr8PDG
Another
Children with Long COVID had measurable retinal microvascular changes. https://t.co/eIElYHievL
In 74 kids ages 7–17, scans found wider arterioles, wider venules, and a higher A/V ratio, consistent with endothelial dysfunction.
The eye may help track pediatric Long COVID.
#UWV zet de volgende stap in het afbreken van de rechtsbescherming tegen de te late overheid.
Dankzij tip van @demo_creatie weten jullie nu ook dat de internetconsultatie gestart is!
https://t.co/DhI0Qg6wVz
@surf4children "Really giving it a try" translates to putting serious effort in.
Not trying just because.
Good to know it costs you. And not entirely free (for you). Please consider to require people to pay the minimum covering cost. This can get out of hand on socials?
@surf4children Have a bedbound child with pais. Wasn't using "just" to try.
Nut was trying to correct the first outcome. To much focus on misinterpretation.
Every try cost you money? How much to compensate?
I missed that you shared this before. Afraid many will use it when sharing on X..
@surf4children Yes I will. I could have altered the text.
But was curious how specific it would become when entering more specific data. Really giving it a try/go.
Maybe it was overstimulated ;).
😅
Or the translation from dutch was a factor.
I will try again. But already very impressed!
@surf4children The second time I tried to be more specific.
Let me try again later this week when it is less busy.
I let you know.
Thank you. I loved the way it puts everything together. And treats mecfs long-COVID seriously. Like it should.
@surf4children Thank you. Yes ofcourse preliminary. It worked the 1st time very well. So maybe it was to busy.
The 1st time I explained incidental use of a medicine due to side effects. It suggested discussing more daily use (misinterpreting side effects for symptom the medicine treats).
1/2
Beyond brain fog: viral proteins as convergent drivers of neuroinflammation and proteinopathy
🚨“COVID-19 never really leaves your brain.”
New science review proposes SARSCoV2 viral proteins stay behind as long-lived toxins, triggering chronic neuroinflammation and planting the seeds of Alzheimer’s and Parkinson’s, even after mild infection.
This very interesting and eye-catching GERMAN review reframes post-viral neurological syndromes( L0ngC0vid) as driven by persistent viral proteins acting as long-term toxins ("protein-as-pathogen" model), not just the active infection!
➡️Core mechanisms:
- SARSCoV2 Spike and OTHER viral proteins activate glial TLR4/TLR2 receptors, triggering chronic neuroinflammatory cascades via NLRP3 inflammasome,
- They also disrupt autophagy, allowing toxic protein aggregates (tau, amyloid-beta, α-synuclein) to accumulate and seed neurodegeneration,
➡️SARSCoV2 specific evidence:
- Animal studies show Spike protein alone (without live virus) induces TLR4-mediated cognitive deficits, memory impairment, synaptic loss, and sustained neuroinflammation, recapitulating post-COVID syndrome,
- Spike binds α-synuclein, accelerating Parkinson-like clumps,
➡️Human data evidence:
- Millions experience "brain fog,"
- Post-COVID patients exhibit measurable brain damage: cortical thinning, hippocampal iron accumulation, and biomarkers of ongoing neuronal injury,
➡️Broader risks:
- Even mild infections leave lingering proteins that promote Alzheimer’s and Parkinson’s-like pathology via shared pathways,
- Same pathways seen in influenza, dengue, West Nile etc,
- Mild infection = no protection,
‼️So, according to this review, the “protein-as-pathogen” model makes it crystal clear: every new SARSCoV2 infection (even mild or asymptomatic) deposits more of these long-lived toxic viral proteins into the brain. They don’t fully clear. They accumulate.
Each reinfection reloads the TLR4/TLR2 → NLRP3 inflammasome trigger and further collapses autophagy, speeding up the tau/amyloid/α-synuclein proteinopathy and neurodegeneration.
SARS-CoV-2 does not just infect.
It weaponizes its own proteins as long-lived intracellular saboteurs.
Millions are probably already carrying this hidden payload.
This is not brain fog.
This is a silent, population-scale reprogramming of human brains toward dementia-like decline.
The long-term neurological cost will probably dwarf the acute pandemic itself!
#AvoidSars2 #AvoidReinfections
https://t.co/x0oxacaNwl
@surf4children So, yes nice tool ! But maybe needs a little update. When you explain a little to much about exmple a side effect (to prevent advise about some med or prevent a conlcusion) it gave this respons:
Connessione Al non
disponibile. Ecco il sunto strutturato: (and than my info).
@surf4children I tried it twice. 1st time it gave a a really good summary. With some incorrect conclusions so I decided to fill it in a Second time with a bit more nuance/ explanation. Unfortunately it wasn't able to process the second time.
It was nice I was able to share in my own language.