CONGRESS | #EHA2026 | PRESENTATION
Matthew R. Wilson, Beatson West of Scotland Cancer Centre, Glasgow, presents findings from an international retrospective analysis evaluating HD-MTX for CNS relapse prophylaxis in patients with ultra high-risk LBCL receiving curative-intent chemoimmunotherapy (N = 1,923; HD-MTX, n = 872; no HD-MTX, n = 1,051).
HD-MTX did not significantly reduce 3-year CNS relapse vs no HD-MTX in UHR patients (6.6% vs 6.7%; adjusted HR, 0.95). Rates of isolated CNS relapse were also similar with HD-MTX vs no HD-MTX (4.8% vs 6.6%; adjusted HR, 0.81). In propensity score matching (501 pairs), 3-year CNS relapse was 7.4% vs 6.2% (HR, 0.86), and isolated CNS relapse was 5.3% vs 4.5% (HR, 0.83). No benefit was seen in any individual ultra high-risk subgroup. In the matched cohort, 3-year EFS and OS were similar with HD-MTX vs no HD-MTX (73.8% vs 73.7%; p = 0.65 and 82.6% vs 82.7%; p = 0.94).
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#lymphoma #lymsm #MedicalCongress @mattwilson2287
El ejercicio físico no puede quedarse en un consejo de pasillo. Tiene dosis, indicaciones y mecanismo de acción como cualquier fármaco, y en muchas enfermedades es el mejor tratamiento, no solo el complemento. Prescribirlo no es opcional: es medicina basada en la evidencia. @HoyPorHoy@La_SER@Nunodomin
Hans IHC vs GEP for DLBCL COO classification #EHA2026
Large meta-analysis (19 studies, 2247 tumors) to eval noninferiority of Hans IHC to GEP.
Estimated accuracy:
- Hans IHC 90%
- pooled GEP 95%
- 4.5% difference met noninferiority margin
- sens 6.5% / NPV 6.4%
Supports Hans IHC as a practical & reliable procedure for COO classification in DLBCL. Particularly important with pola non-GC data. #lymsm cc @AshAlizadeh@gvencut1
https://t.co/NA59xg9kuY
Our study on patient-reported time toxicity of BsAb in R/R FL & DLBCL:
- 120 pts actively receiving BsAb tx
- fixed-duration BsAb (glofi, mosun) = less healthcare contact days & ~50% less time burden (vs epco)
- no difference in infusion time between IV and SQ
Time-limited & less frequent BsAb dosing translates into meaningful reductions in time toxicity, both in the clinic and at home. #lymsm
https://t.co/ci6lfcT5Ol
💡How can we prevent infections in adult patients receiving bispecifics for lymphoma or myeloma?
Pleased to share our new How I Treat article, just published in @BloodPortfolio 👇
Great experience writing this with @RahulBanerjeeMD and @JoshuaHillMD !
https://t.co/C08M8ZvwE7
Shifting focus to clinical advancements!
Dr. Izaskun Zeberio is currently on stage presenting on malignant hematology, diving deep into the most recent updates and breakthroughs in Hodgkin Lymphoma (HL). Vital insights for our specialized nursing community!
#SSBMT#EBMT #SaudiHemOncNursing #SaudiHematology
Gracias a @Technogym por la invitación al Innovation Outlook en Valencia.
En tiempos donde cada semana aparece un nuevo “crecepelo” de la longevidad —biohacking, suplementos milagro y promesas antiaging— conviene recordar algo simple: la longevidad que importa es la longevidad funcional.
No se trata solo de vivir más.
Se trata de llegar con fuerza, movilidad, autonomía y capacidad funcional.
Y ahí el ejercicio físico y el fitness no son lifestyle. Son infraestructura de salud.
#HealthyLongevity #ExerciseIsMedicine #Fitness #Aging #VIVIFRAIL @CIBER_ISCIII@UNavarra@navarrabiomed@semeg_es@ConsejoCOLEF
Visión desde Hematología del impacto del ejercicio físico adaptado e individualizado en pacientes con linfoma. Gracias al Hospital Universitario de Canarias
por la invitación! #edonola#osakidetza#EHU#Biogipuzkoa
Dr. @majorajay@CUHematology contributed to a multicenter study of nivo-AVD outcomes outside of the clinical trial setting, now published @Hemasphere_EHA. #lymsm https://t.co/Kbj2JqnxAb
International Quality Innovation Conferences Award Ceremony in Donostia . Innovations in Health Care
Award Winner: Donostialdea Integrated Health Organization (IHO)- Basque Health Service (Osakidetza) Basque Countr #osakidetza#osidonostialdea#Biogipuzkoa Team effort!
Stage IA NLPHL outcomes @glow_nlphl
- 779/2243 pts Stage IA
- completely resected: better PFS if +RT
- unresected: R monotx & ABVD with worse PFS as compared to RT +/- ABVD
- not enough N to analyze R-CHOP
RT alone great option in both resected & unresected dx. #lymsm
https://t.co/i6SX235oo0