Jack Markham

Medicinal & Computational Chemistry PhD Student with a focus on Cannabinoids 👨‍🔬🧪🧬🖥️

[Jack Markham @JackMarkhamPhD]

@endless_sine touching glass

[Eric Sparkes @eric_sparkes]

It's all things adamantane in our (@Lambert_Usyd) latest synthetic cannabinoid work, out now in @ACSChemNeurosci!

We synthesised and evaluated a library of adamantane-derived SCRAs, including fluorinated and deuterated analogues 🧪
🧵
https://t.co/yq4EPZPvyZ

[Eric Sparkes @eric_sparkes]

More SCRA work from @Lambert_Usyd out now in @rsc_medchem!

We looked at a series of proteinogenic amino acid-derived SCRAs related to MPP-5F-PICA, MMB-5F-PICA, and MDMB-5F-PICA, investigating the role of chirality in CB1 and CB2 receptor activation.

https://t.co/IpUb6vpCRH

[Eric Sparkes @eric_sparkes]

Latest work from @Lambert_Usyd is online in @ACSChemNeurosci!

In another great collaboration with @christophestove et al., we looked at the recently detected synthetic cannabinoid ADB-HEXINACA and related analogues as emerging NPS🧪🔍

https://t.co/Sra7FCUERl

[Jack Markham @JackMarkhamPhD]

@lewischewis Schrodinger uses red/blue for HBD/HBA I believe

[Lambert Initiative @Lambert_Usyd]

“You’ve got a bizarre situation in which you can grow opium poppies behind a farm fence, but if you grow cannabis you need [secure] facilities and dogs,” 🗨️ @iainsmcgregor

Read @JordsBaker's @smh feature on #medicalcannabis ft. the Lambert Initiative👐

https://t.co/tDkhPrPZN5

[Eric Sparkes @eric_sparkes]

Our latest paper from @Lambert_Usyd on 4-fluoro and 4-cyanobutyl substituted synthetic cannabinoids is online today!

tl;dr: most compounds assayed were moderate to high potency and efficacy CB1 agonists, and should be monitored as emerging NPS 🧪🔍

https://t.co/Y060uFDIi4

[Jack Markham @JackMarkhamPhD]

@proberting SHE'S BACK!!

[Lambert Initiative @Lambert_Usyd]

📚🤓 First Journal Club for 2022 @ LI, it's been a long time coming but now we can finally argue in person!

Ft. Maia yelling at @EA_Cairns, @MA_BEDOYAPEREZ, @TheCannabisGuyy, Ayshe, @JackMarkhamPhD, @eric_sparkes, Tom, Sam and @DuckyMcCartney 🥳

[Jack Markham @JackMarkhamPhD]

@hourlyFox @KremlinRussia_E something to think about

[Jack Markham @JackMarkhamPhD]

@JennieandClair1 @SpiritofHo

[Jack Markham @JackMarkhamPhD]

@JaiRelan @WuCarra @AriannaSimpson @TextsHQ Done

[Jack Markham @JackMarkhamPhD]

@JaiRelan @WuCarra @AriannaSimpson @TextsHQ Hey mate, any chance you could spare one of those invites?

[Jack Markham @JackMarkhamPhD]

@jr_desert @dauphinb @SteveHerring32 @DigiEconomist Yes database

[Jack Markham @JackMarkhamPhD]

@jr_desert @dauphinb @SteveHerring32 @DigiEconomist This thread is about actual problems blockchain solves, not a thread about car crashes being bad.

[Jack Markham @JackMarkhamPhD]

@jr_desert @dauphinb @SteveHerring32 @DigiEconomist Bill said authenticity doesn't matter for something like shoes, which isn't wrong, but maybe doesn't apply for brake pads. We can all agree we don't want to die in a crash. So, original q, why is blockchain better than a db for this?

[Jack Markham @JackMarkhamPhD]

@bryangkelley @SteveHerring32 @DigiEconomist

[Jack Markham @JackMarkhamPhD]

@Blockchimp @IrishBitcoinGuy @SteveHerring32 @DigiEconomist

[Jack Markham @JackMarkhamPhD]

@Blockchimp @IrishBitcoinGuy @SteveHerring32 @DigiEconomist If you mean govt seizure of assets then I'm sorry but that happens constantly.

If you mean seizure by other people, the fact that theirs no third party to reverse fraudulent charges means it's actually way easier to lose your shit with no recourse.