Jacob Hamm

MD, Clinician Scientist, University Medical Center Goettingen @yourUMG, Department of Gastroenterology

[Jacob Hamm @jacobhammx]

Great to see the PROTOCOL trial finally published in Endoscopy. Key message: Too many of our pat. w/ acute pancreatitis and LAMS take PPIs and this is associated w/ worse outcomes in regard to LAMS occlusion and necrosectomies. @albrechtneesse @AmmerHerrmenau

[Christoph Ammer-Herrmenau @AmmerHerrmenau]

🥳👉Very happy to share our latest paper @endoscopyjrnl

🙌Great team effort from 17 🇪🇺centers

PPI 💊 intake lead to ↗️ LAMS occlusion and ↗️ necrosectomy rates addressing WONs but 🩸complication same as No PPI

What is your practice?

https://t.co/5yEVKZr8r8

[Jacob Hamm @jacobhammx]

Excited to present the first data from our microbial multi-omics pipeline at #UEGW in Barcelona! 🥳 See you there!

#chronicpancreatitis #PDAC #microbiome @albrechtneesse @AmmerHerrmenau @my_ueg

[Jacob Hamm @jacobhammx]

The realization of this application of course would not have been possible without @albrechtneesse and @AmmerHerrmenau. This project will be a great team effort together with Johannes Zimmermann from Jena, the Proteomics Core Facility of the UMG and the DKFZ Heidelberg 🦸‍♂️

[Jacob Hamm @jacobhammx]

Very honored to receive 95k of funding from the University Medical Center Goettingen Research Program for our Multi-Omics project trying to identify novel microbial signatures to differentiate between IPMN, chronic pancreatitis and pancreatic cancer. 🥳
https://t.co/DbALdb6HXU

[Jacob Hamm @jacobhammx]

Within our project we aim to integrate ONT sequencing, in silico-prediction of microbial metabolites, proteomics and targeted metabolomics to gain a holistic view of the microbiome which goes beyond sequencing only.

[UEGJ @UEGJournal]

🩺Dual-modality drainage lowers mortality in necrotising #pancreatitis

DRACULA study (585 pts, 29 centres):
🔸 Drain flushing ≠ better outcomes
🔸 Antibiotics ≠ saline
🔸 Percutaneous + internal drainage ↓ mortality

📖 #OpenAccess 👉 https://t.co/PV5E31BaNs

@my_ueg

[Jacob Hamm @jacobhammx]

We wrote a short overview on the role of the microbiome in pancreatic diseases - now published in Verdauungskrankheiten 🥳
https://t.co/WeGxnHbOij @albrechtneesse @AmmerHerrmenau

[Gut Journal @Gut_BMJ]

Read the #GUTOnline paper by Ammer-Herrmenau et al on

"Gut microbiota predict development of postdischarge diabetes mellitus in acute pancreatitis" via

https://t.co/RlynnyujJV

#Pancreatitis #DiabetesMellitus @albrechtneesse

[Christoph Ammer-Herrmenau @AmmerHerrmenau]

🚨paper alert

💥Our P-MAPS follow-up in @Gut_BMJ
🔑 Points
-15🇪🇺centers
-⏰3y follow-up
-Early 🦠 in AP predicts post🏥 mortality and diabetes🍬

@albrechtneesse @emadelomar
#PMAPS #pancreas #microbiome

[Else Kröner-Fresenius-Stiftung @EKFStiftung]

Acute pancreatitis is life-threatening—and there is currently no treatment available. A global study is examining the gut microbiome of 700 patients. @albrechtneesse and his team aim to identify biomarkers and new therapeutic approaches. https://t.co/l5gqxz0dXb

[Jacob Hamm @jacobhammx]

Excited to see this one out 💪🏻 Glad to have contributed together with @AmmerHerrmenau

[Marlies Vornhülz @mvornh]

So proud that our latest DRACULA trial is now online! 🦇🙌
✅ 585 patients, 29 centers, with percutaneous drainage in necrotizing pancreatitis

https://t.co/kD9A5RCBfY

#pancreatitis #LMU #myUEG

[Enrique de-Madaria @DeMadaria]

1/3
Guys, if you are in Berlin in the #UEGweek @my_ueg, we invite you to attend on Monday 10am Room A4 the session "From The Lion King to Waterland: A journey through pancreatitis"

We will show the final results of the #WATERLANDtrial, largest RCT in pancreatitis ever

[Endoscopy Journal @endoscopyjrnl]

Investigating PPI use and outcomes in LAMS-treated pancreatic necrosis

Find the article at: https://t.co/FaNSE1TMLs

Jacob Hamm et al.

[Jacob Hamm @jacobhammx]

@ShivKSingh6 @dfg_public @kfo_5002 @Krebshilfe_Bonn @SanderStiftung Congrats Shiv & Team, impressive work! 💯

[Enrique de-Madaria @DeMadaria]

Our friend @albrechtneesse talking about microbiome and acute pancreatitis during @EurPancClub meeting Dusseldorf

Awesome talk!

[Sara Nikolić @SN_gastro]

Now the prince of microbiome 🦠 with a little bit different topic this time:

Are PPIs associated with more occlusion of LAMS?

yes!!! ⬆️sour the juice 🍋 - ⬇️ necrosecomies, no more GI🩸

If you prescribe them, give the lowest dose.

#EPC2025

@YouppiePancreas @EurPancClub

[Jacob Hamm @jacobhammx]

@SN_gastro @YouppiePancreas @EurPancClub @AmmerHerrmenau @albrechtneesse @lelecapurso @ESGE_news Or simply don’t prescribe them if not indicated otherwise 😋 🍋🍋

[Christoph Ammer-Herrmenau @AmmerHerrmenau]

💥1st global 🦠trial on AP

🥳We’re thrilled to announce that with the start of recruitment in 🇦🇺, P-MAPS II has officially gone 🌍! With over 300 pat. enrolled

👉AIM: 700 pat.

🙏for incredible commitment and collaboration of all P-MAPS II members

[ESGE @ESGE_news]

What a milestone! @endoscopyjrnl, our official organ, has reached an impressive Impact Factor of 12.8 for 2024. Today´s leading journal in #GIEndoscopy!
Kudos to the whole editorial team lead by Ed-in-Chief @DSiersema and Co-Eds-in-Chief @mdinisribeiro & Heiko Pohl.

[Lucía Guilabert @Lguilabert1]

Take a look of our last published paper in @AmJGastro
✅Symptoms reported by patients👫 are a 🔑 tool to predict AP severity comparable to BISAP
✅ PANPROMISE is a great outcome for AP trials🕵🏼

https://t.co/UgJj2fgQT3

[Lumír Kunovský @LumirKunovsky]

🔥Effect of #PPIs 💊 on occlusion of lumen-apposing metal #stents & rate of #endoscopic #necrosectomies ⚫️

🚨PPI intake was associated w/
⬆️ rates of LAMS occlusion ⛔️ & necrosectomy❗️

📘 only in @endoscopyjrnl 🤗
👉https://t.co/feuKgJvB0c

🔵 @ESGE_news 🔵
⚪️ @ThiemeIntl ⚪️