James Stewart

[James Stewart @james_jamstew]

@TechCrunch Nice! Does it provide handicap access?

[James Stewart @james_jamstew]

The cells that line the inside of the gut — known as intestinal epithelial cells — may play a key role in triggering inflammation that drives multiple sclerosis (MS), a study showed. The study found that these cells can activate a type of T-cell known as Th17 cells.

[James Stewart @james_jamstew]

Immune Cells Linked to Epstein-Barr Virus May Play a Role in MS https://t.co/HkiKvaB3PL

[James Stewart @james_jamstew]

The investigational BTK inhibitor fenebrutinib was as effective as the approved therapy Ocrevus (ocrelizumab) at reducing the risk of disability progression in people with primary progressive multiple sclerosis (PPMS), meeting the main goal of a Phase 3 trial. Genentech

[James Stewart @james_jamstew]

Myelin is repaired by constitutive differentiation of oligodendrocyte progenitors | Science https://t.co/OJUdMg331x

[James Stewart @james_jamstew]

A brain protein called ANO2 has emerged as a new piece of the puzzle linking Epstein-Barr virus (EBV) infections and MS damage. https://t.co/jLAIM4Boiu

[Craig Brockie @CraigBrockie]

Two bacterial species kept showing up in higher numbers in MS-affected twins:

• Eisenbergiella tayi
• Lachnoclostridium

Both live in the ileum (small intestine), where inflammatory T cells gather before attacking the brain.

This location matters more than you think.

[James Stewart @james_jamstew]

Scientists Trace Lupus to One of The World's Most Common Viruses https://t.co/ckfbsy4gE0 via @@YahooNews

[James Stewart @james_jamstew]

Two Phase 3 trials testing the investigational oral therapy fenebrutinib in people with multiple sclerosis (MS) have hit their main goals. https://t.co/jyh0UZYa5R

[James Stewart @james_jamstew]

Tr1X has won an FDA green light for a clinical trial testing TRX319, a cell therapy designed to restore immune balance, for progressive MS. https://t.co/oovKef5caf

[James Stewart @james_jamstew]

The FDA gave Hope Bioscience's stem cell therapy RMAT designation after clinical data suggested it may improve life for adults with RRMS. https://t.co/GDB8A03dEG

[James Stewart @james_jamstew]

Susan Payrovi, MD, and Mirla Avila, MD, discuss early gut microbiome formation and its lifelong influence on MS and immune function. https://t.co/RWTkv0SQFE

[James Stewart @james_jamstew]

The experimental CAR T-cell therapy treatment was given as part of a clinical trial that's enrolling adults with progressive forms of MS. https://t.co/LrX1yvWcUH

[James Stewart @james_jamstew]

A mouse study showed a link between an infection with herpes simplex virus type 1 (HSV-1), the cause of cold sores, and MS. https://t.co/mL4Q97s57g

[James Stewart @james_jamstew]

Mesenchymal stem cell therapy lessens disability and brain lesions in MS patients, according to a review of published studies. https://t.co/PpJwGKYdR7

[James Stewart @james_jamstew]

Neural stem cell treatment was safe and significantly boosted myelin repair in spinal cord lesions in a mouse model of MS, per a study. https://t.co/DWtMZFVZcg

[Samuel Hume @DrSamuelBHume]

Top 5 advances in medicine this week (🧵)

1. Adults can produce new neurons, after all

A decades-old problem is whether adults can produce new neurons. It’s been proven in mice – but never in humans

This is the stunning discovery that the full pathway of new neurons - from the stem cells to the neuroblasts – can be found in the adult hippocampus

Neural stem cells are the ‘parent’ cells, intermediate progenitor cells are the ‘children’ and neuroblasts are the ‘teenagers’ – on their way to becoming fully-formed neurons

Source: https://t.co/PgijcXTpQg

[James Stewart @james_jamstew]

The MIND diet plan, rich in whole grains, leafy greens, berries, and lean proteins, may improve antioxidant defenses in MS, per a study. https://t.co/yhuHdgjgmA

[Rep. Mike Thompson @RepThompson]

The big, ugly bill is getting uglier. New analysis shows the Senate’s version of the bill will cost taxpayers $4.2 trillion dollars — even more than the cost of the House’s version of the bill. This is a bad deal for the American people. https://t.co/DxkBl6jN5o

[Rep. Mike Thompson @RepThompson]

Congressional Republicans held a hearing today titled “Health at Your Fingertips.” It’s hard to take that seriously when they are working to rip health care out of the hands of 16 million Americans.