James Halle-Smith

General Surgery Registrar and Gut Microbiome Researcher

[Gut Journal @Gut_BMJ]

New #GUTScience paper by Halle-Smith et al entitled

"Gut microbiome composition is associated with response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma patients" via

https://t.co/DJBfeCp05e

#OA #PancreaticCancer @druppygill

[James Halle-Smith @jameshallesmith]

Two people can receive the same chemotherapy and have completely different experiences.

Emerging evidence suggests that bacteria in the gut may contribute to the development of side effects.

This article explores the recent evidence and mechanisms ⬇️

https://t.co/YCCijDJm9c

[Mary Phillips @MaryHPBRD]

Are you a dietitian, Interested in doing a PhD and love the pancreas - then this is for you https://t.co/cja51MH6vd
@RoyalSurrey @GutsCharityUK @PancSocGBI

[James Halle-Smith @jameshallesmith]

@CholestasisDoc @adbeggs @beggs_lab Thank you Prof!

[James Halle-Smith @jameshallesmith]

Thank you @adbeggs, very grateful for the support from @beggs_lab

[Andrew Beggs @adbeggs]

Very proud of @jameshallesmith who is a clinical PhD supervised by @UHB_HPB and @beggs_lab for winning the Rodney Smith Medal @ThePancSocGBI meeting this week on “Pancreatic Exocrine
Insufficiency is associated with Gut Microbiome
Dysbiosis in Patients with PDAC”

[James Halle-Smith @jameshallesmith]

Thank you to all those who contributed to and supported this research @beggs_lab @unibirm_CMH @UHB_HPB @adbeggs @TariqFMT @ThePancSocGBI @uhbtrust @PancreaticCanUK

[James Halle-Smith @jameshallesmith]

💡Does the gut microbiome affect how well neoadjuvant chemotherapy works in pancreatic cancer patients?

Our study just published in @Gut_BMJ science investigates how the gut microbiome differs according to chemotherapy response🧵

https://t.co/HSPcAcCorX

[James Halle-Smith @jameshallesmith]

What does this mean? ⏭️

Altering the gut microbiome towards a more favourable phenotype has the potential to increase efficacy of existing chemotherapy drugs in pancreatic cancer. This could potentially be achieved through dietary modification or FMT

https://t.co/pcKweC4a3W

[David Naumann @davidnnaumann]

Doctors: use vignettes! 🧵

You’ve done a gazillion exams and what do all patient-based questions have? That’s right, a clinical vignette.

Heres a secret in medicine: you can use the “skill of the vignette” to get what you want and to communicate better than ever.

[Matthew Armstrong 💙 @Drfattyliver]

Time to get fit and raise money. At 44yr it’s time to experience emotions of the @LondonMarathon 2025. Raising money for @PancreaticCanUK and privileged to be doing so. @UHBCharity @uhbtrust @unibirmingham @EASLnews @ExaltTrial #livertwiiter @AASLDtweets https://t.co/Qo9m5ogUqI

[James Halle-Smith @jameshallesmith]

@surgicalsheel @Drsampathak @roux_group @UHB_HPB Thank you @surgicalsheel that’s really kind and very happy to hear that you have enjoyed the series

[James Halle-Smith @jameshallesmith]

4th session in the national pancreatic cancer webinar series for trainees and fellows.

This week’s first talk from the Leeds team and @Drsampathak talking about surveillance and recurrence after pancreatic cancer surgery @roux_group @UHB_HPB

[Andrea @surgicalsheel]

@jameshallesmith @Drsampathak @roux_group @UHB_HPB What a fascinating discussion. Really insightful experience shared from some really big names in UK HPB surgery. This webinar series had be really great and I have throughly enjoyed participating. Well done everyone involved 👏🏻

[James Halle-Smith @jameshallesmith]

All hands to the pump! ⛽️🤲

Birmingham NRP team practising troubleshooting at the fantastic Edinburgh NRP masterclass 2024 @Bham_HPB_LTx @CentreEdinburgh

#NRPMasterclass

[James Halle-Smith @jameshallesmith]

Session 1: Bristol ✅
Session 2: Liverpool ✅
Session 3: Birmingham ✅
Session 4: Leeds ✅

Talks from experts at pancreatic units all over the UK as part of the webinar series for trainees and fellows on pancreatic cancer.

Second talk of this evening from Prof Smith (Leeds)

[David Bartlett @DaveCBartlett]

Great to see so much participation from the Birmingham HPB surgical team during the HPB sessions at #AUGIS2024! @Augishealth @uhbtrust @Bham_HPB_LTx @UHB_HPB @liveRPancSurg