James Bryson

LEAD Postdoc fellow @UCPH_BRIC | Mammalian synthetic biologist specialised in CRISPR tool development | Data scientist

[James Bryson @jameswbryson]

Great to share our experience with the Marie Curie LEAD postdoc fellowship. We fellows and administrators of the leadership skill-oriented program pass along recommendations to postdocs, PIs and institutes invested in cultivating the next generation of leaders in academia!

[Jamie Auxillos @jamieauxillos]

Thrilled to share our paper where we integrated
@10xGenomics #Visium #SpatialTranscriptomics in a #microfluidics workflow to explore how pH gradients in the #TumourMicroenvironment impact #cancer cells.

[Jamie Auxillos @jamieauxillos]

7 days left to apply for our #postdoc position on RNA modifications at the University of Copenhagen!

If you’re interested in combining #CRISPR with #nanopore direct RNA sequencing to explore the role of #RNAmodifications in #RNAdegradation, apply here!

https://t.co/JbQNa10D4f

[Hannah Currant @HannahCurrant1]

Excited to be @KulturnattenKbh @UCPH_Research where we are making DNA bracelets, helix origami 🧬 and competing in our CRISPR challenge ✂️with @UCPH_CPR and @UCPH_BRIC

[Sophia Hafner @SigmaJuly]

Finally!!!
Tuning ribosomes and cell differentiation with one single methylation - check out our latest publication from @therealLundLab :
https://t.co/bKiqkm54UL

[Centre for Engineering Biology @EdEngBio]

Great feature on our new start up Concinnity Genetics & founders @JessicaCBirt @MattDale21 Improving the safety & efficacy of gene therapies using #AI they form part of a vibrant local ecosystem that will underpin future mammalian engineering biology. Thanks @scotent @UKRI_News

[James Bryson @jameswbryson]

This work was done at the University of Edinburgh as part of my PhD - @SBSatEd @SynthSysEd. Thanks to all my colleagues who helped out with this work! @tessa_moses, @MattDale21, @JessicaCBirt, Trevor Ho, @ewjwallace and @youvegotmyname

[James Bryson @jameswbryson]

Just in time for Christmas! New publication with @RosserLab and @jamieauxillos in @NAR_Open where we show the generation and characterisation of an FnCas12 derived synthetic transcription factor in mammalian cells: https://t.co/ejTIUbboS4

[James Bryson @jameswbryson]

We show multiplexed transactivation, order dependent activity of crRNAs within an array and generate a functional split intein version able to retain activity when expressed from two separate plasmids (opening up the potential for AAV delivery)

[James Bryson @jameswbryson]

@ErikaSzymanski Surely you’re not suggesting there’s a better metaphor than blueprints to describe genetic material?
#rhetoricalquestion

[Erika Szymanski @ErikaSzymanski]

I'm hiring! Help me spread the word?

[James Bryson @jameswbryson]

Thanks to the @RosserLab and @tessa_moses for all the support you’ve provided throughout my PhD!

[James Bryson @jameswbryson]

Excited to share a biorxiv pre-print from my PhD work in Edinburgh @SynthSysEd ! We characterised different Cas12a derived synthetic transcription factors and show multiplexed transactivation with dFnCas12a-VPR in mammalian cells: https://t.co/vgPB3Fv4TG

[James Bryson @jameswbryson]

...and it’s done! Thesis submitted and ready to be defended. Just wanted to give a shout out to @tessa_moses Susan and everyone at the @RosserLab