Excited to share our new paper on #microproteins in @MolecularCell !
Thousands of non-canonical ORFs are translated across the genome, potentially encoding a vast “dark proteome” of uncharacterized proteins.
But which ones are actually functional?
https://t.co/Hzr3EVc6ne
Had fun talking with @TheScientistLLC about our latest work in @CellCellPress minimizing unintended chromosome loss during CRISPR-Cas9 genome editing!
Check out the full paper here: https://t.co/NxDqKbtuMt
I’m looking for a PhD-level scientist to join my research group @Vir_Biotech. We work on exploratory projects in molecular virology and virus-host interactions across multiple viral pathogens with the goal to uncover new therapeutic approaches. https://t.co/VV546sJMoG
So excited to share our recent work! It has been an absolute pleasure collaborating with @marcoyannic and all authors! Please see Marco’s fantastic tweetorial 🧵
🚨 New #LoveVirology preprint:
This paper has it all: single cells, COVID, CRISPR & Sunshine!
We systematically characterize host factors of SARS-CoV-2 using Perturb-seq.
Led by @sarasunshinebio, bringing together @JswLab, Joe DeRisi's lab & many others
https://t.co/9AXfXKeEYc
1/
Malaria kills 0.5 million people/year, partly because immunity to malaria is developed inefficiently. Excited to share findings from my postdoctoral work where we identify that repeated amino acid stretches in Plasmodium antigens could be a reason. https://t.co/QMV0H5keEq
1/ In @SciImmunology we report that about 25% of vaccinated patients with critical C-19 pneumonia and a normal Ab response to the vaccine have high levels of auto-Abs to type I IFN (https://t.co/x5gA8Wzy6m).
Finally, none of this would have been possible without the amazing team I got to work with @andreaspuschnik, @bioelze, @sarasunshinebio
and many others without a twitter account 🍾🍾🍾
Our paper is out in @mbiojournal, and I can't be more excited!
Check out our work in identifying and characterizing CD164 as an entry factor for LCMV:
https://t.co/d7n9es4xMV
👇🧵 by @jamesknunez from our biorxiv preprint
This paper by @glycobrotein, @vsv512 and others showed similar findings... and they also demonstrated direct interaction between CD164 and LCMV-GP! 🎉
https://t.co/8tx5pfaksf