Jason Comander MD PhD

Ophthalmologist & scientist, Director of the Inherited Retinal Disorders Service @MassEyeandEar @harvardmed

[Jason Comander MD PhD @JasonComander]

New England Journal of Medicine paper released today - what started as the first in vivo clinical trial for CRISPR gene editing, for CEP290-associated retinal degeneration. Congrats to all. @MassEyeandEar @harvardmed @HMSeye @CaseyEye @editasmed #ARVO2024 https://t.co/lSH8jo3tyj

[Jason Comander MD PhD @JasonComander]

@ImtiazMadmood Dayenu

[Jason Comander MD PhD @JasonComander]

Congratulations Kannan and team! I’m very proud of you and the data looks amazing. We discovered over 800 mutations in rhodopsin - triple the number in ClinVar from all prior submissions. Special thanks too to the @OctantBio team for advancing RHO research.

[Kannan Manian @KannanManian3]

Presenting our work on "Deep mutational scanning reveals the pathogenicity and structural insights into rhodopsin missense variants" was a true privilege. Huge thanks to Octant Bio and Dr.Jason Comander, whose guidance was instrumental to this project.#ARVO2024

[Mass Eye and Ear @MassEyeAndEar]

The vision of 22-year-old Olivia Cook has improved, and so has her hope for the future thanks to an experimental gene-editing treatment called #CRISPR. Learn more about the groundbreaking study from lead investigator Eric Pierce, MD, PhD: https://t.co/VVZJWMDPOQ via @CNN.

[Jason Comander MD PhD @JasonComander]

@NEJM Congratulations to all involved! Also see https://t.co/xi6kdYXghX

[Jason Comander MD PhD @JasonComander]

https://t.co/QLyE8TycPC

[Jason Comander MD PhD @JasonComander]

Restoring vision using CRISPR gene editing https://t.co/lSH8jo3tyj #ARVO2024

[Jason Comander MD PhD @JasonComander]

https://t.co/QLyE8TycPC

[Jason Comander MD PhD @JasonComander]

New England Journal of Medicine paper released today - what started as the first in vivo clinical trial for CRISPR gene editing, for CEP290-associated retinal degeneration. Congrats to all. @MassEyeandEar @harvardmed @HMSeye @CaseyEye @editasmed #ARVO2024 https://t.co/lSH8jo3tyj

[Jason Comander MD PhD @JasonComander]

@autpops @nateinthewild This is the best video ever- it is yours?

[Jason Comander MD PhD @JasonComander]

How to safely view an eclipse! The pinhole projector is more fun than the glasses! https://t.co/G2aLIelZkB

[Harvard Ophthalmology @HMSeye]

Link to learn more and register: https://t.co/kEV9045T3P

[Harvard Ophthalmology @HMSeye]

Faculty member @JasonComander will be discussing the latest Stargardt’s research and the biological basis of the disease at the virtual Stargardt’s Summit next Wednesday, February 29.

[Jason Comander MD PhD @JasonComander]

@FightBlindness Thanks so much Ben for having me on the show! Glad to give an update on vitamins and RP. I’m not used to talking about myself so much but hope people enjoyed the stories and info!

[Foundation Fighting Blindness @FightBlindness]

Are you ready for our final Eye on the Cure episode of 2023? In this week's episode, host Ben Shaberman chats with Jason Comander, Md, PhD.

Learn more about streaming at: https://t.co/JtOlHLgZbB

[thereishope66 @thereishope66]

VIDEO: Gene therapy for X-linked retinitis pigmentosa shows positive safety, efficacy data.
https://t.co/9IVk96EOtW

[Mass Eye and Ear @MassEyeAndEar]

Usher syndrome is a hereditary condition responsible for nearly half of all deaf-blindness cases. Today, on #USHDAY, Mass Eye and Ear researchers Zheng-Yi Chen, DPhil, and Qin Liu, MD, PhD lend their expertise on the disease: https://t.co/CpL4UF0wm0

[Jason Comander MD PhD @JasonComander]

@RetinaToday There is no room on twitter for a sophisticated rebuttal, but suffice to say that many specialists in the inherited retinal disease field would strongly disagree. It’s just not true- gene therapy will continue to help our patients.

[Jason Comander MD PhD @JasonComander]

@MoodCritic @JohnDoench If you want low MOI, we noticed that "dialing down" lentivirus to 1 copy per cell works much better than for AAV. I think, because 1 copy of successfully-transduced lentivirus gives higher detectable expression than one copy of active AAV. Depends on the cell type though.

[Jason Comander MD PhD @JasonComander]

@growingwisdom @ColbyCollege I think it’s great but would there be more risk of ticks for people brushing into it walking by?

[Amy Comander MD, FACLM, DipABLM @DrAmyComander]

Today I saw a patient that is seeing the other Dr. Comander- that would be my amazing husband, retina specialist & physician scientist @JasonComander, in just a few weeks…… I think this is the first time we have shared a patient!