Jay Chandar

[Sylvester Comprehensive Cancer Center @SylvesterCancer]

Christian K. Ramsoomair, a fifth-year M.D./Ph.D. student at @umiamimedicine, has been awarded the prestigious @theNCI F30 fellowship to advance cancer research at Sylvester. 🙌 Discover how mentorship at Miller School and Sylvester is shaping the future of cancer research: https://t.co/lbqEqzF6Xx
@CKRamsoomair @AshishHShah4 @ReinbergDanny

[Victor M. Lu MD PhD @victorlumd]

A while coming, our NIH R25-funded work on GBM LMD was published exposing the TLR-4 pathway as relevant, and more importantly for me, lays foundations for active cerebrospinal fluid (CSF) exchange studies to make clinical change. @AshishHShah4

[Ashish H. Shah @AshishHShah4]

Congrats to our amazing MD PhD student @CKRamsoomair on receiving his NCI F30 grant this week to study pediatric brain tumors! Chris is an rockstar student, scientist and friend! We’re lucky to have him in the @um_svilab! He is co-mentored w/ the epigenetic guru @ReinbergDanny

[Ashish H. Shah @AshishHShah4]

Great talk by @CKRamsoomair discussing the role of neurosurgeons in brain tumor clinical trials! Christian is a rising superstar in neurosurgery! @UMneurosurgery @um_svilab

[Ashish H. Shah @AshishHShah4]

Thrilled that we are enrolling for STARLITE phase 1 trial for newly diag. unresectable GBM. We will combine FDA-approved antiretroviral drugs +Laser ablation+SOC. The trial leverages the anticancer effects of ART to target treatment resistant GBM stem cell niche.
NCT06428045

[UM SVI LAB @um_svilab]

Congrats @CKRamsoomair! Excited for your talk at @AANSNeuro!

[Starke_neurosurgery @Starkeneurosurg]

Really excited about this awesome group!

[Journal of Clinical Investigation @jclinicalinvest]

Tapping ancient viral DNA in the treatment of glioblastoma!

@AshishHShah4 @SeetharamDeepa @jaychandar5 & team @umiamimedicine show the zinc finger protein ZNF638 activates viral mimicry to promote immune checkpoint inhibition in preclinical models of glioblastoma: https://t.co/YXXZkcs4eH

[Jay Chandar @jaychandar5]

It’s a dream come true to join this amazing program. Thank you to everyone at UM for this opportunity and for all of your support. Can’t wait for these next 7 years. @UMneurosurgery @AllanLeviMD @Ricardokomotar @AshishHShah4

[Allan Levi, MD, PhD @AllanLeviMD]

So excited about our incoming 2025 class! Congratulations, Dr. Megan Sharpe, Dr. Andrew Wang, Dr. Jay Chandar and Dr. Daksh Chauhan! Welcome to @UMneurosurgery ! 🙌
#matchday #neurosurgery

[OncoDaily @oncodaily]

Suppressing Key Protein May Unlock Immunotherapy for Glioblastoma
@SylvesterCancer @AshishHShah4 @jaychandar5

https://t.co/Z2sRilULZr

#OncoDaily #Oncology #Cancer #Health #Medicine #Immunotherapy #MedTwitter #MedEd #MedOnc #MedNews

[UM Neurosurgery @UMneurosurgery]

📢 STARLITE Phase 1 Study.
Groundbreaking clinical trial to explore a potential new treatment for unresectable high-grade gliomas. This study aims to assess how these tumors respond to a combination of MR-guided Laser Interstitial Thermal Therapy (LITT) and antiretroviral drugs.

[Ashish H. Shah @AshishHShah4]

Thrilled to share our @um_svilab work published today in @jclinicalinvest focused on harnessing viral mimicry to activate immunotherapy for #GBM. Thanks to all of my @SylvesterCancer @UMneurosurgery colleagues for their invaluable contributions!
https://t.co/nB4bcsFuFc

[Allan Levi, MD, PhD @AllanLeviMD]

Challenging resection of a large C7 intramedullary hemangioblastoma that had undergone previous biopsy at an outside hospital.
@EvaWuMD
Angio Embo - Ty @Starkeneurosurg
#Neurosurgery

[Ashish H. Shah @AshishHShah4]

Lot of things to be grateful for this week in the lab!
1. @SeetharamDeepa @jaychandar5 got their paper accepted on activating immunotherapy !
2. @VaidyaGovind15 received a training grant to study GBM exosomes !
3. @CKRamsoomair recent operative pub on virotherapy techniques!

[Ashish H. Shah @AshishHShah4]

Happy holidays from @um_svilab ! Blessed to have such a wonderful motivated and fun team! 🥼Holiday 🍕 party at Casa de Shah. Delicious chocolate cake courtesy of @GarciaNevett @UMneurosurgery @SylvesterCancer @SeetharamDeepa @CKRamsoomair @jaychandar5 @VaidyaGovind15

[Ashish H. Shah @AshishHShah4]

Excited to share our @biorxivpreprint focusing on epigenetic potentiation of immunotherapy for #GBM through viral mimicry! Congrats @jaychandar5 @CKRamsoomair @DeepaSeetharam for their hard work and all our colleagues who contributed to this manuscript!
https://t.co/Fg7PW0A9pQ

[bioRxiv Cancer Bio @biorxiv_cancer]

Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma https://t.co/EoeCjkanHR #biorxiv_cancer

[Ashish H. Shah @AshishHShah4]

Great time @CNS_Update in HOU! We had a great time learning about cutting edge neurosurgery and presenting our brain tumor work! Also congrats to Ray Castro from @SylvesterCancer for winning top tumor poster! @JustinTaylorLab @um_svilab @UMneurosurgery @jaychandar5 @CKRamsoomair

[Jay Chandar @jaychandar5]

@akashjp330 @AshishHShah4 @FloridaNeuro @um_svilab @UMneurosurgery @SeetharamDeepa Thanks Dr. Patel!

[Ashish H. Shah @AshishHShah4]

Congrats @jaychandar5 for winning best medical student research presentation at the @FloridaNeuro society meeting this weekend!! @um_svilab @UMneurosurgery @SeetharamDeepa