We assayed the subcellular localization of ~3,500 missense variants of >1,000 disease-associated genes, comparing the localization of variant and reference (wt) proteins. Computational and manual annotation of images identified 250 mislocalized variants for >150 phenotypes. 2/
Amazing overview of endothelial cell metabolism by Dr. Michael Potente, recipient of the 2023 NAVBO Folkman Award! 🏆
Congratulations to all the awardees!! 🥇
@potente_michael#NAVBO2023
🥳😀We are very happy that our collaborative research center on "Cardiovascular noncoding RNAs" @trr267 is extended for the next 4 years! Many thanks to @dfg_public for allowing us to continue exploring the RNA world with our great team @goetheuni @LMU_Uni @MHH_life @mpi_hlr
Now online: 🌟"Normalizing career choices outside academia"🌟
@Sciezgin from @karolinskainst/@scilifelab urges academic scientists to normalise non-academic careers and stop penalising scientists choosing these paths. Read his thoughts here:
🔗https://t.co/SRaYOELPWN
New insights in vascular endothelial cell development & diversity from single-cell genomics and in vivo genetic labeling https://t.co/IEj5LDlXch @NatRevCardiol E. Trimm @kristyredhorse@StanfordMed
This time, TAZ has a leading role (vs #YAP), coupling #NutrientSensing with retinal #Angiogenesis🤠
⏫TEAD-dependent transcription of AA transporters SLC7A5, SLC1A5, etc->
⏫mTORC1 activity
Dr. Michael Potente lab @NatMetabolism 2022 @potente_michael
https://t.co/0HkVhkodrM
Our paper showing how genetic/microenvironmental heterogeneity impacts colorectal cancer progression is finally published! Thanks to our friends and collaborators who made this work possible! @UCIBIO_Research @IMMolecular
https://t.co/c2a7LdekGD
Interested in #regenerativebiology? We are looking for TWO motivated PhD students to join our new lab at the @jlugiessen on the topic of heart regeneration. Both positions are fully funded by the #DFG. Please spread the word. #phdpositions#Zebrafish https://t.co/68U3nVBmG6
We are happy to accounce openings for two professorships! Contact me if you are interested! With the excellence cluster CPI and the DZHK #goetheuniversity#Frankfurt is the perfect place for cutting edge CV research from basic science towards #translation. #jobs#hiring
Students, postdocs, if you are interested in understanding how cells sense their environment and like the combination of experimental and computational technologies, then apply to MDC’s recent recruit, Yoichiro Sugimoto: https://t.co/7k7P1jMBYi
📢 Join a fantastic team and benefit from the excellent training program in our new integrated research training group - check our website https://t.co/v544RYfn3M for available PhD positions in various projects! Don`t miss this chance! @goetheuni@mpi_hlr@MDC_Berlin@uni_mainz
🔆JUNE issue🔆
A nice mix of topics, including angiogenesis (on the cover), several papers on #cancerresearch, BAT & #inflammation, autoimmune diseases, as well as periphery to #brain crosstalk on #feeding behavior. Enjoy!
https://t.co/yMoEvjAID9
Hungry blood vessels: A team effort led by Yu Ting Ong reveals how endothelial cells regulate nutrient acquisition during angiogenic growth. Read more about our latest work in @NatMetabolism under the following link: https://t.co/IdYS3jMiXu
If you are interested in blood and lymphatic vessels, this is the place to be: the Kloster Seeon “Angiogenesis” Meeting. Cutting-edge biomedical research in a beautiful setting close to the Bavarian Alps. There are still a few slots available: https://
https://t.co/GQVCP7JlFy