DrTammiR

Biochemist, infectious disease guru, loyal Syracuse sports fan, and intrepid traveler. Views are my own and not my employers

[Carolyn Barber, MD @cbarbermd]

BREAKING: VIRUS FROM NEVADA DAIRY WORKER WITH BIRD FLU HAS THE SAME GENETIC MUTATION seen in the Nevada cows – a change of PB2 D701N that has previously been assoc with more efficient virus replication in ppl &  mammals.

@CDCgov told @FortuneMagazine that the D1.1 variant in this worker is the same strain of the virus that likely also infected 15 PEOPLE across Iowa, Louisiana, Oregon, Washington and Wisconsin in 2024. This change was previously identified in a human case in Chile in 2023. No other changes assoc with mammalian adaption were identified in the sequence data of the Nevada case.

The CDC didn't identify any changes in the sequence data from the NV person that might impact antigenicity or susceptibility to antivirals. However, the virus will undergo further analysis & testing.
Updated story:🎁Gift link: https://t.co/SKInR5rOLy @RickABright @HNimanFC @EricTopol @DrEricDing @CIDRAP @Fieldsish

[BNO News @BNOFeed]

Updated numbers on unidentified illness in Congo:

- 382 suspected cases, 71 deaths
- 27 died at healthcare centers, 44 at home
- Around 300 people have already recovered
- Current number of active cases unclear
- Children under 5 represent 40% of cases

[Sayed Abdel-whab (ORCID: 0000-0003-2103-0922) @Sayedabdelwhab]

Excellent study and alarming: H2N2 avian flu shows mutations enhancing mammal infection but limited transmission. Risk of a pandemic is low, but surveillance and preparedness are key. https://t.co/YgAZRuvRyV"

[Voices for Vaccines @Voices4Vaccines]

"One out of every 200 babies who catch whooping cough will die. Their lungs are too small to whoop - they simply stop breathing during an attack."

Why a breakthrough case taught her vaccines matter. https://t.co/uZwvgZFkOJ

[NFID @NFIDVaccines]

Although #RSV is typically associated with young children, it can also impact older adults, and is estimated to cause up to 160,000 hospitalizations and 10,000 deaths among adults age 65+ each year in the US

Learn more: https://t.co/G8iVHsFRkl #OlderAmericansMonth

[DrTammiR @jctar1]

@VisitHouston @blayzur This was my #Htown view on my way to the airport.

[DrTammiR @jctar1]

Who needs TSwift when you can have Jake!!! #GoBirds

[Jake from State Farm @JakeStateFarm]

In my red era with Mama MaAuto

[DrTammiR @jctar1]

@PHLEaglesNation Love it!!! An Eagle slaying this Eagles song!!

[DrTammiR @jctar1]

@EnemyInAState There are many mdx tests that are commercially available that don’t use the CDC primers/probes. Also, mfgs look at whether or not sequence variations could have an impact on their test and if likelihood is high based on in silico analysis they do testing with that strain.

[Kai Kupferschmidt @kakape]

Mammal-to-mammal spread of highly pathogenic avian influenza is pretty high on the list of things I really don’t want to read about happening…

[syracuse.com @syracusedotcom]

No. 18 SU is 6-0, and bowl eligible, after a 24-9 win over No. 15 N.C. State https://t.co/FxfKxQEBAC

[DrTammiR @jctar1]

This is my dream match up!! Go Bills Go Birds!!!

[y - Ben Mathewson @Ben_Mathewson]

Our nation simply doesn’t posses the infrastructure required to handle a Bills Eagles Super Bowl.

[BNO News @BNONews]

Argentina investigates outbreak of unidentified illness https://t.co/gQE8HVaZAL

[DrTammiR @jctar1]

@iah This was my view yesterday!! #windowviewofIAH #united

[DrTammiR @jctar1]

Such a great discussion on the BA.5 potential impacts. Especially since I’m likely suffering from BA.5 this round (after OG in 2020 and BA.2 in April). It’s no joke, albeit not as bad as OG was for me (healthy 40 something), been sick for 10 days now.

[Bob Wachter @Bob_Wachter]

Covid (@UCSF) Chronicles, Day 838
The die is now cast: BA.5 is destined to be our dominant virus.
In today’s 🧵I discuss the implications on the course of the pandemic, and how to think about responding.
(I use “BA.5” & not “BA.4/5” since BA.5 is poised to outrun BA.4.). (1/25)

[DrTammiR @jctar1]

I have a feeling we are going to be in for a doozy of a Flu season in the US this year too…

[DrTammiR @jctar1]

Is anyone else wondering if we’ve been missing these infections previously or is this truly a new phenomenon?

[Infectious Diseases @InfectiousDz]

Monkeypox, metropolitan areas:

- London, GB: 9 confirmed
- Lisbon, Portugal: 14 confirmed, 6 suspected
- Madrid, Spain: 23+ suspected (1 ex-Canary Islands)
- Quebec, Canada: 13 suspected
- Boston, MA, USA: 1 confirmed
- Stockholm, Sweden: 1 confirmed
- Rome, Italy: 1 identified

[Eric Topol @EricTopol]

Just published @Nature
Omicron BA.1 infections induce narrow immunity (just to BA.1) in people without vaccination, but when combined w/ vaccination cross-immunity to Delta and other variants
https://t.co/Q0GHT2MDfD by @sigallab @KhadijaKhan24

[Craig Spencer MD MPH @Craig_A_Spencer]

As Omicron recedes in NYC, the benefit of the vaccines is so incredibly clear.

They prevented infections.

And reduced hospitalizations A LOT.

And drastically lowered the likelihood of dying from Covid.

This wave was tough. Without the vaccines, it would’ve been so much worse.

[Eric Topol @EricTopol]

The original vaccine-induced T cell response (via mRNA or J&J) is durable vs Omicron
https://t.co/ov8dBZjmiG
"current vaccines may provide considerable protection
against severe disease w/ the Omicron variant despite the substantial reduction of neutralizing antibody responses"