Most Likely Diagnosis: Deep Vein Thrombosis (DVT)
โ Diagnosis: Deep vein thrombosis
Why this fits the case
The clinical picture shows:
Unilateral leg swelling
Erythema
Localized tenderness
These are classic features of Deep vein thrombosis.
The presence of a central venous catheter significantly increases the risk because it can cause venous endothelial injury and blood flow disturbance.
Pathophysiology
DVT develops due to Virchowโs triad:
1. Venous stasis
2. Endothelial injury
3. Hypercoagulability
Common Risk Factors
Central venous catheters
Prolonged immobilization
Surgery or trauma
Cancer
Pregnancy
Oral contraceptive use
Major Complication
The most feared complication is Pulmonary embolism, which can be life-threatening.
Diagnosis
The first-line investigation is:
Compression Doppler ultrasound
Management
Treatment usually includes:
Anticoagulation therapy (e.g., heparin, DOACs, warfarin)
Early mobilization and monitoring for embolic complications
โ Concise Answer:
> Deep vein thrombosis โ unilateral leg swelling and erythema in a high-risk patient, confirmed with Doppler ultrasound.
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