Jesse Erasmus

Director of Virology @hdtbio. Developing RNA platform for emerging infectious diseases. 🇿🇦🇰🇷

[Jesse Erasmus @jesseerasmus]

🧵 New in @ScienceTM and on the cover! https://t.co/zbaH92M1Vu After developing RNA vaccines for several different enveloped viruses, we realized that no one had done so for nonenveloped viruses. In this paper, we sought to do just that, with a focus on a prototype picornavirus.

[Jesse Erasmus @jesseerasmus]

Great collab to understand how antibodies elicited by our LION/repRNA vaccine against #CCHFV nucleoprotein mediate protection via an intracellular TRIM21 interaction. Turns out non-neutralizing antibodies can be neutralizing if they can get inside cells. https://t.co/GCe9xrJsAh

[Jesse Erasmus @jesseerasmus]

Feeling quite positive about this trip to Killarney, Ireland! Looking forward to some good science

[Jesse Erasmus @jesseerasmus]

Our CCHF and NiV programs continue to hit milestones. Looking forward to continued success!

[Jesse Erasmus @jesseerasmus]

Excited to announce our contribution to NIAID’s ReVAMPP initiative as part of Albert Einstein College of Medicine’s PROVIDENT consortium. Both press releases linked below.

https://t.co/nrmqLMd2Kh

https://t.co/lViK4CTKx3

[Jesse Erasmus @jesseerasmus]

@RealBenCotton 😂

[Jesse Erasmus @jesseerasmus]

Calling all mucosal immunologists. We are hiring a postdoc to join our team. Looking for someone interested in characterizing mucosal responses to our platform and understanding how and why they are better than those elicited by LNP vaccines.
https://t.co/JXIUdOTEyL

[Jesse Erasmus @jesseerasmus]

Preprint on our work with NIAID/RML to understand vaccine composition requirements for protection against bovine H5N1, should it become a problem. TL;DR: HA from the stockpiled vaccine may not be ideal.

[Greg Folkers 🇺🇦☮️🇺🇸 @greg_folkers]

Research Square: Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine #H5N1 challenge

David Hawman, Heinz Feldmann et al

👉https://t.co/l1BRo9ppjE

[Jesse Erasmus @jesseerasmus]

If anyone access to the full copy of this paper, head over to https://t.co/3hICGclNJl and use the special link there! (only allowed to provide the link in one place)

[Jesse Erasmus @jesseerasmus]

1/12 Enterovirus D68 (EV-D68), part of the Picornaviridae family, transmits through respiratory droplets. Since 2014, it's been linked to over 756 cases of acute flaccid myelitis in the US, mostly affecting children; highlighting the urgent need for an effective vaccine. #AFM

[Jesse Erasmus @jesseerasmus]

12/12 Shout out to 1st author @DrNikkiWarner21, and @JFArcher who led most of the work, and co-authors on twitter (@KhandharAmit @Taishi_Kimura @VogtVirusLab) and not (Stephanie Park et al) for contributing to massive effort. Stay tuned for more updates! #scienceresearch

[Science Translational Medicine @ScienceTM]

A self-amplifying mRNA vaccine for enteroviruses shows promise in mice and large animals, researchers identify a plant-based compound that could combat hearing loss from powerful antibiotics, and more this week in #ScienceTranslationalMedicine. https://t.co/Pc30HPd831

[Anna Blakney @AnnaBlakney]

Our lab's new publication, led by Nuthan and Josh, investigates whether the route of administration and delivery vehicle impacts the protein expression from saRNA.
https://t.co/Wvv6OWWk37

[Dr. Angela Rasmussen @angie_rasmussen]

I sure do love to see the picornaviruses getting some attention. Great work here 👇

[Matthew R. Vogt @VogtVirusLab]

I’m pumped to see this work in print! Congrats to the @hdtbio crew on a very cool EV-D68 vaccine. This was a fantastic way to debut our #AFM mouse model. Glad you brought us on and congrats on getting the cover, to boot!