James Dooley

[Politics For You @PoliticoForYou]

BREAKING 🚨🚨🚨

Nicola Sturgeon urged to apologise after leaked WhatsApp messages describing Matt Hancock as “Weaker than a nuns piss,” Liz Truss as “About as much use as a marzipan dildo,” and referring to Suella Braverman as “Shitler.”

[Adrian Liston @LabListon]

@PascalBielefeld @FitzFitzsimons @UvA_Amsterdam @sebastianmunck @BioImagingCore What next? We'd love to move into a #clinicaltrial. All the pieces are in place (thanks @ERC_Research PoC!) and the tech can be directly translated. Each year 50 million #traumaticbraininjury patients need treatment, and families need hope. 10/12

[Adrian Liston @LabListon]

@PascalBielefeld @FitzFitzsimons @UvA_Amsterdam @sebastianmunck @BioImagingCore The great thing about this approach is that #Tregs are smart anti-inflammatory agents, able to deal with many different types of stress. We could hit with models of #stroke or #multiplesclerosis and saw the same protective effect! 8/12

[Adrian Liston @LabListon]

The system increases #brain #Tregs 10-fold, creating an anti-inflammatory environment. With @PascalBielefeld @FitzFitzsimons @UvA_Amsterdam we tested in #traumaticbraininjury, and the results were immediate - we were able to prevent most neurological damage! 7/12

[Adrian Liston @LabListon]

We teamed up with Matthew Holt @CBD_VIB @i3S_UPorto to design a system to feed extra #IL2 into the brain. The gene delivery system harnesses #genetherapy technology and #astrocyte biology, to bring brain IL2 levels up to the same level as the blood. 6/12

[Adrian Liston @LabListon]

We had a great post-doc, @EmanuelaPasciu1, drive a project showing #Tcells in mouse and human brain, with key functions. Among these T cells were a small population of anti-inflammatory #Tregs, again in mouse and human. 3/12
https://t.co/2UYn8L5m1E

[Adrian Liston @LabListon]

The work started more than 10 years ago, after my brother Russell died following a #traumaticbraininjury. The more I read into it, the more treatable #neuroinflammation seems. Obviously there is a #brain delivery problem, but stopping #inflammation is basic #immunology! 2/12

[Adrian Liston @LabListon]

Excited to share our new paper out at @NatImmunol today! We discovered the limiting factor for #brain #Tregs is #IL2, and developed a new #genetherapy to treat #traumaticbraininjury and other #neuroinflammatory pathologies. 1/12

https://t.co/EpDUyZnlOw

[James Dooley @jldvib]

@dkm14 Hope you are staying in Seattle!

[James Dooley @jldvib]

@Bwagz The fans adore you. We all are grateful for your time with us. The "Legion of Boom" and Beast Mode brought the Superbowl trophy to Seattle. Much respect!!

[James Dooley @jldvib]

@BorisJohnson @ZelenskyyUa I would like to think that Boris is genuine. I just don't buy it. He is saying what he says to look good. It is camouflage for action. All the actions taken so far are proposals with slow can complex implementation criteria. Looking beneath the surface all looks superficial.

[James Dooley @jldvib]

@justinbaragona What a crock. I do agree we would not be here today because Trump was doing what Putin and Xi Jinping wanted. Leaving NATO and destroying alliances with the EU and aligning with authoritarian governments. Democracy takes work too. Thank you Biden for restoring these priorities.

[James Dooley @jldvib]

Help me win a Women in Science Puzzle from Nature https://t.co/atmZSlYMzi

[Babraham Institute @BabrahamInst]

We are currently seeking a Postdoctoral Research Scientist in Bioinformatics to work on an exciting international immunology project.

Apply by Thursday 22nd April

Full details: https://t.co/lqgadK3z5l
Lab group: https://t.co/rBtp4uob6P
#ScienceJobs #PostdocJobs #Immunology

[Brian Tyler Cohen @briantylercohen]

Watch this. Trust me.

[Adrian Liston @LabListon]

I gave an #AcademicJobs talk @UAlberta yesterday. My aim was to lift the veil on applying for academic research positions, negotiating a start-up and making the first steps in your new lab.

Excessive honestly will likely land me in hot water, but...
https://t.co/RhgelSDCrl

[Floreada Cytometry @FloreadaCyto]

It's finally here! https://t.co/Z6U6eEKVhQ now supports automatic compensation via Autospill (thanks to Dr. Roca and @LabListon). This was by far the most requested feature and we are excited for people to try it out. #flowcytometry #autospill

[Marc Van Ranst @vanranstmarc]

Interview in @nrc: over de grote gelijkenissen en kleine verschillen tussen de Belgische en Nederlandse aanpak van de Covid-19 crisis. https://t.co/ZPiM9paOYB

[Adrian Liston @LabListon]

If anyone would like to hear more about #IL2 #cytokine networks, #Treg feedback circuits and the curious linkage between #Bcells and #CD8Tregs, I just gave a talk on our pre-print story from @CarlyEWhyte and team: https://t.co/mxZn8MEIOA

The talk is here: https://t.co/ypZNrlopGh

[James Dooley @jldvib]

@jules_su As much as I feel there is plenty of dumb things this President has done. It is far more important to highlight the policy and court appointments that have been done since 2016 as these will have a real and lasting effect. Focusing on things like this is merely distracting us.