JMC

Indie Dev | Web & iOS

[JMC @jmc_dev]

@itsolelehmann Halfway through brain surgery and you see this

[JMC @jmc_dev]

Imagine hitting your usage limit in the middle of a surgery

[Ole Lehmann @itsolelehmann]

wtf

this guy just had Claude Sonnet 5 perform brain surgery on a living mouse

the goal was to treat the mouse's epilepsy so it would stop having so many seizures.

here's what Claude did:

> it looked at 19 possible treatments and picked one that boosts the brain's natural calming chemical

> it chose where to inject it based on where these seizures are thought to start

> it worked out the exact injection point by averaging three research papers

> it lowered the needle 4.3 millimeters into the mouse's brain

> it injected a 20,000th of a teaspoon of the treatment over five minutes

> it checked the live camera 32 times to watch for things like bleeding

and the mouse woke up and recovered well!

interestingly, Opus 5.5 and Opus 5 both refused the task because it involved real biology

so Sonnet 5 got the job.

and as far as the researcher knows it's the first time an AI has picked a treatment and then injected it into the brain of a living mammal.

[JMC @jmc_dev]

When he seemed to remember the details about everything except the one day/time period he needed to remember to prove his innocence, it was obvious he was guilty. The podcast does a great job of making you question everything though

[Laura Robinson @LauraRbnsn]

Have you guys ever gone back and listened to Season 1 of Serial and thought "wait, why did we think he was innocent?"

[JMC @jmc_dev]

@MaxHirsch13 They may only have friends and family in their own country, so when you look at reviews and ratings from your country they don't appear

[JMC @jmc_dev]

@swyx I feel like design is where agents still need the most help, they can build the feature fine but everything ends up looking like the same template

[JMC @jmc_dev]

@OpenAI Seems like the models are gonna keep finding these gaps before the people setting up the sandboxes do

[JMC @jmc_dev]

@claudeai This is the kind of thing that makes the Duo actually worth it, most apps just stretch the phone layout at the moment

[JMC @jmc_dev]

@ThomasBurkhartB I do find it suspicious that they never mention or show the app that got them banned

[JMC @jmc_dev]

I don't think most people using open weight models need them to beat opus, they just need them good enough for the small stuff at a fraction of the cost https://t.co/k1ZZMIIvni

[Theo - t3.gg @theo]

Terrible day to be an “open weight models are just as good as Opus 5.5” guy

[JMC @jmc_dev]

@expo Didn't expect expo to have duo support this quick, makes it way easier to just do it now instead of waiting until april

[JMC @jmc_dev]

@BrandonButch It's crazy that it starts at $2,899, most people would still be better off with an air and an ipad

[JMC @jmc_dev]

Seems like most people just go with whatever the agent suggests, I do it too when both options look fine https://t.co/Tlqgv1ySKz

[Alex Tamkin @AlexTamkin]

New Anthropic research: How AI agents shape experts' judgment calls

When experts delegate work to an agent, do they still make the key decisions? We tested this in a randomized trial with 50 professional data analysts.

[JMC @jmc_dev]

Even he has a human assistant because companies still want to deal with a person, I think that's what agents won't replace for a while https://t.co/tmILkJiTCK

[TechCrunch @TechCrunch]

Alexander Embiricos, the OpenAI executive responsible for dots, never wants to have a meeting with someone else's AI agent.
https://t.co/mX8JRflAn6

[JMC @jmc_dev]

Seems like nobody really knows what to do with these results yet, most people can't even check if they're right

[Theo - t3.gg @theo]

Never seen ChatGPT get so serious so fast before

[JMC @jmc_dev]

@MaxHirsch13 I feel like most onboarding gets confusing because it asks too many questions before you've even seen what the app does

[JMC @jmc_dev]

@levelsio I think apps stick around longer than people think, most people still don't trust an agent with anything important

[JMC @jmc_dev]

@kr0der It's just the codex computer use tools that are better, but you can ask claude to use codex computer use

[JMC @jmc_dev]

@petergyang Is terra actually better at coding or just faster? Seems like it was pitched more for computer use

[JMC @jmc_dev]

@levelsio I think the links are a big part of it, most people don't trust an answer unless they can see where it came from

[JMC @jmc_dev]

@cursor_ai I'd probably use this for small tasks and save opus 5.5 for the harder stuff