Jon Magnus

PGY-2 @IMResidencyDuke - interested in all things microbiology; views entirely my own; he/him

[Mike Carolla @SJTimes13]

this entire scene from KOTFM was brilliant. I was absolutely terrified and couldn’t explain why

[Jon Magnus @jmicrobe9]

@TeeHallums What worries me more is that such a poorly conceived game with soulless design and dull gameplay is being so overhyped. This game won’t have any lasting effect on the video game landscape outside of opening the floodgates for more AI-generated dreck with “a twist”.

[Jon Magnus @jmicrobe9]

@LttleGel @kaylamellis_ Diet Coke isn’t associated with mass outbreaks leading to hospitalisations. That would be raw milk.

https://t.co/JgjTxDkSiZ

[Jon Magnus @jmicrobe9]

@stonedpomgrante @ReadsA_lot @kaylamellis_ Hilarious if you think that proves anything.

Colds develop because of our immune response to viruses we are exposed to. Mild colds tell me that my immune response is doing as it should.

[Jon Magnus @jmicrobe9]

@stonedpomgrante @ReadsA_lot @kaylamellis_ Man, so predictable.

Those reports come from individual state health departments. Are you saying they are all lying to make raw milk look bad? Now, that’s wild.

[Jon Magnus @jmicrobe9]

@stonedpomgrante @kaylamellis_ Yeah - pretending raw milk hasn’t caused serious outbreaks is truly wild.

https://t.co/JgjTxDkSiZ

[Jon Magnus @jmicrobe9]

@stonedpomgrante @kaylamellis_ Then they didn’t have lactose intolerance or that milk had very little lactose in it. Either way, lactose intolerance is due to inactivity of lactase. If the milk has lactose, it will cause problems, regardless of pasteurisation.

Pasteurisation simply removes pathogens.

[Jon Magnus @jmicrobe9]

@ReceiveandStab Yet the Switch remains my most played console with the best library of games since the PS2. Nintendo doesn’t need to outperform in technical prowess, they’re already ahead where it truly matters.

[Jon Magnus @jmicrobe9]

@ThatSamWinkler Portal 2 remains one of the games I regard as literally flawless - it has not one thing I can malign. Humor is subjective, but I have a strong feeling these posts are heavily affected by some altering of minds.

[Jon Magnus @jmicrobe9]

@BrandonLBradfor These are most likely the same people that think Mensa is “cool” instead of one of the most embarrassing groups out there.

[Jon Magnus @jmicrobe9]

@MaddenDude_ @eemoin @ENirenberg We lack screening tools for most clinical diagnoses - that doesn’t stop us from making them. The definition of sepsis from S-3, along with how we gauge organ dysfunction, are both crystal clear. S-3 mostly emphasizes that we should not be calling any marked immune response sepsis

[Jon Magnus @jmicrobe9]

@MaddenDude_ @eemoin @ENirenberg I have no qualms with it be used as an adjunct, knowing its limitations. I’ve only ever seen it used within the context of the old S-2 criteria. S-3 didn’t endorse qSOFA as a replacement, but a tool to research further. 1/2

[Jon Magnus @jmicrobe9]

@firdeboer_85 @eemoin @ENirenberg Neither qSOFA nor SIRS are appropriate screening tools. S-3 only proposed that qSOFA be analysed as a screening tool, not be wholesale adopted. The guidelines continue to emphasise that SIRS does not define sepsis anymore.

[Jon Magnus @jmicrobe9]

@MaddenDude_ @eemoin @ENirenberg Assuming we can diagnose a complex pathophysiologic process based on an arbitrary 4-point score was inappropriate to begin with. Instead of continuing to use SIRS, we should be focusing on how to triage patients into the sepsis pathway in an evidence-based manner. 2/2

[Jon Magnus @jmicrobe9]

@MaddenDude_ @eemoin @ENirenberg I think S-3 is more specific and less confusing than anything that came before it. SIRS is an awful diagnostic tool because of poor specificity and has unacceptably low sensitivity for a screening tool (~90% in the ICU). Problem is, most people didn’t read S-3. 1/2