Jody Mou

MIT PhD student @mit_hst | protein design w/ Polizzi Lab @DFCI_CancerBio | 🇨🇦

[Nick Polizzi @nickpolizzi_]

Do you use self-labeling proteins (SLPs) like HaloTag and SNAP-tag? Then check out Jody's new preprint to learn about LUCI-tag! Jody built LUCI-tag starting from K-Ras(G12C), using protein design to erase K-Ras from biology 🤯!

[Jody Mou @Jody_Mou]

Thank you to everybody who contributed to this project, especially my PI @nickpolizzi_ and many wonderful collaborators at @DFCI_CancerBio @broadinstitute @insitubiology for their amazing support! (16/16)

[Jody Mou @Jody_Mou]

Excited to share a preprint of my main PhD work in @nickpolizzi_'s lab - introducing LUCI-tag, a new orthogonal self-labeling protein tag based on K-Ras(G12C) and its covalent inhibitors! https://t.co/vdID57bs3t (1/16)

[Jody Mou @Jody_Mou]

We hope LUCI-tag will be a helpful tool to the research community. Sequences are available in our preprint, along with a simple HPLC-free click chemistry protocol to generate imaging probes from commercially available reagents. (15/16)

[Possu Huang Lab @PossuHuangLab]

Our sequel review paper titled “Sparks of function by de novo protein design” is now out in @NatureBiotech!

@alexechu_ @Tianyu_Lu

Full-access link here:
https://t.co/DXEBNbF3KH

[Alissa Hummer @AlissaHummer]

Last month, I had the privilege to attend the @KeystoneSymp conference on Computational Design and Modeling of Biomolecules in beautiful Banff, Canada (📸).

I wrote a blog post with my takeaways on the current state of protein design:
https://t.co/Khu5fHXS1Q

Overview in 🧵

[Boston Protein Design and Modeling Club @ProteinBoston]

exciting news to share: we are going to resume having in-person meetings in 2023! (we will continue to stream all seminars for our community members outside of Boston)

stay tuned for details, which will be posted to our new website https://t.co/XmUzYso2fG