Jon Lieff MD -- Searching for the Mind Blog

New Book: The Secret Language of Cells: What Biological Conversations Tell Us About the Brain-Body Connection, the Future of Medicine, and Life Itself!

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

β‑arrestin proteins, regulate GPCR activity, assemble into liquid-like clusters known as condensates both at baseline and near activated receptors. droplet-like structures act as hubs that organize signaling molecules in space and time. https://t.co/Vwj3ljNUar

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

The fast flow of glymphatic system moves at a few microns per second around the brain's open regions, while the slower flow of the waterlike fluid trickles through the brain's deep tissue at a rate about 50 times slower. https://t.co/49m8v58hoD

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Most people assume dreams are brief, fragmented flashes. In fact, the evidence suggests otherwise. REM sleep dreams appear to unfold roughly in real time. https://t.co/xALwTj1d13

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

DNA constantly absorbs UV light from the sun, which can potentially trigger harmful chemical reactions. However, DNA is remarkably photostable—meaning it can rapidly deactivate excited energy states before lasting damage occurs. https://t.co/m4r1IqgFw4

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Cells use both RNA interference and heterochromatin to detect and silence transposons, with recognition efficiency based on insertion location (where in the genome the transposon is) and copy number https://t.co/Nswv8xH0O2

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Experimental mRNA vaccine shows promise against multiple Ebola strains https://t.co/Vm44609Iac

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Tau—a protein widely associated with memory loss in dementia—is essential for organizing and stabilizing memories so they persist over time. https://t.co/ssTXXsDgLs

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

or over 130 years, psychoanalysis has developed psychological theories about how predictions take place at a subjective level, which cognitive neuropsychology is now studying at a physiological level https://t.co/HTYzebnP9M

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

When gabapentin given to mice weeks after single psilocybin dose, after psilocybin's own pain-relieving effect had worn off, it produced pain relief up to four days. In mice that had not received psilocybin, gabapentin's effect much weaker. https://t.co/R8Wz50raNr

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

The constantly changing cell scaffold signals with all motors and organelles making it possible for mind to flow through molecules in nature

https://t.co/h1MEKEdHjZ

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Its flexible bonding from constantly moving, dancing strands of disordered proteins that make it possible for mind to flow through molecules in nature

https://t.co/BxUnkN8CA6

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Its flexible bonding of layers of water to every molecule in the cell that produces unique structures that constantly change and make it possible for mind to flow through molecules in nature

https://t.co/8xD6RldyH6

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Its flexible bonds that make it possible for mind to flow through molecules in nature

https://t.co/36Eb2fZgCq

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

How can a molecular creature that walks with two feet like humans find out what to transport to an exact location hundreds or thousands of steps away

https://t.co/2nCeB2dVkK

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

For now, best-supported ways to support healthy aging remain regular exercise, good sleep, a balanced diet, avoiding smoking, limiting alcohol. evidence much stronger for everyday habits than for anti-aging products https://t.co/E9J0U0wv8P

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Animals do not simply eat more when nutrients are lacking. Instead, the brain selectively adjusts feeding priorities to favor the nutrients that are specifically deficient. https://t.co/o5VOP1SipV

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Cows show a visual preference for new human faces over a familiar one and can match a known handler's voice to their face, https://t.co/sARr2F8d48

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

The most Intelligent Motor walking on two feet like a human on microtubules across the cell knows exactly where to deliver mitochondria, lysosomes, and chromosomes

https://t.co/2nCeB2dVkK

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Alzheimer's patients, the researchers made a crucial discovery: a specific group of disease-associated immune cells (known as microglia) that accumulate specifically in a particular form of typical protein deposits (amyloid-β plaques) https://t.co/h2ix6gwj5M

[Jon Lieff MD -- Searching for the Mind Blog @jonlieffmd]

Dynein – A Very Talented Walking Communicating Molecular Creatures Operates as a Node in a Cell Wide Intelligence Network.

https://t.co/2nCeB2dVkK