Jonathan Misskey

Proud father of twin girls, husband, vascular and endovascular surgeon at Vancouver General Hospital, program director ubc vascular and surgical foundations

[NEJM @NEJM]

Original Article: Selpercatinib in Early-Stage 𝘙𝘌𝘛 Fusion–Positive Non–Small-Cell Lung Cancer (phase 3 LIBRETTO-432 trial) https://t.co/5D8USAzd7h

#ASCO26 | @ASCO

[NEJM @NEJM]

In patients with pulmonary embolism, ultrasound-facilitated, catheter-directed fibrinolysis led to a lower risk of a composite of major adverse outcomes than anticoagulation alone. Full HI-PEITHO trial results and Research Summary: https://t.co/2EUkQM91GT

[Annals of Surgery @AnnalsofSurgery]

Exploratory analyses demonstrated higher 2-year survival after open surgery compared with primary amputation among patients with end-stage kidney disease and chronic limb-threatening ischemia. https://t.co/CCwMsyY0FK

[NEJM @NEJM]

Presented at #ASCO26:

Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq

@ASCO

[Liam Brunham @LiamBrunham]

One-and-Done Heart Disease Prevention? Scientists Show It May Be Possible. https://t.co/BOV184A5oz

[Jonathan Misskey @JonMisskey]

@BehindTheKnife @Kniery_Bird Make a bigger incision

[Jonathan Misskey @JonMisskey]

@mattsmeds Very interesting study. Would be helpful to know whether retinal strokes/vision loss counted as strokes. Not as dramatic as hemispheric events but can still be devastating.

[UMassVascular @UMassVascSurg]

18 years ago we burnt a hole in an endograft for a single renal artery to repair (turned down for open repair) her juxtarenal aneurysm. Fast forward-we are discharging patients POD 1 after 3 vessel arch with percutaneous femoral puncture & radial puncture. Absolute magic.

[Farhad Udwadia @frudwadia]

Check out our study - Perspective of Liberian surgical care providers on ethical issues in global surgical collaborations @PLOSONE

@EmilieJoos @scarzad
https://t.co/nz7Ab3q4Bt

[Jonathan Misskey @JonMisskey]

Congratulations UBC's own Dr. Ibrahim Al Kindi (with @frudwadia) as this years 2026 Top Gun technical skills competition at the Winnipeg Vascular and Endovascular Symposium. Good luck in Florida! @UBCVascular

[JAMA @JAMA_current]

Med News: New lipid guidelines from @ACCinTouch and @American_Heart adopt earlier screening and intervention, a new risk calculator, updated risk categories, LDL-C targets, one-time universal Lp(a) testing, and other reworkings. Find out more: https://t.co/V3k9SUSjfJ

[NEJM @NEJM]

In the phase 3 OCEANIC-STROKE trial involving patients with noncardioembolic ischemic stroke or high-risk TIA, asundexian added to antiplatelet therapy led to a lower risk of ischemic stroke without increasing major bleeding. Full trial results: https://t.co/UPJGedYXFe

Editorial: Asundexian for Noncardioembolic Ischemic Stroke https://t.co/V1dVNbx4T8

[NEJM @NEJM]

In cisplatin-ineligible patients with muscle-invasive bladder cancer, enfortumab vedotin–pembrolizumab plus surgery led to better event-free survival (74.7%, vs. 39.4%) and overall survival (79.7%, vs. 63.1%) than surgery alone at 2 years. Full phase 3 KEYNOTE-905 trial results and Research Summary: https://t.co/bzVbmJXHMD

[NEJM @NEJM]

Presented at #ACC26:

Among patients with infrainguinal artery disease who were undergoing angioplasty, the risk of major adverse limb events at 1 year was lower with sirolimus-coated balloons than with uncoated balloons, and mortality was similar. Full phase 3 SirPAD trial results: https://t.co/q0me2qDhtj

Editorial: Sirolimus-Eluting Technology for the Treatment of Peripheral Artery Disease https://t.co/OIyR2PAKgo

@ACCinTouch

[Stroke AHA/ASA @StrokeAHA_ASA]

🧵#STROKE Guidelines in Action 🗒️: For patients with large core infarcts, EVT is recommended for all eligible patients to improve functional outcomes and reduce mortality. Expanding EVT indications will require adaptation of acute stroke systems of care.

[NEJM @NEJM]

Presented at #SVIN25:

CREST-2: In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit. Full results: https://t.co/ojge1CjqiU

Editorial: Managing Asymptomatic Carotid Stenosis https://t.co/D9LH89Edyk

@svinsociety

[JVS - Venous and Lymphatic Disorders @JVSVL]

"Could birth control protect your veins?

Jain et al found that women on systemic progestins—with or without estrogen—needed significantly fewer procedures for varicose veins.

📄 Read more in JVS-VL, July 2025."
https://t.co/7do1CkeWoa

#veins #VenousEd #JVSVL#vascularsurgery

[David G. Armstrong follow @dgarmstrong.bsky.social @DGArmstrong]

In limb-sparing amputations, should cartilage be preserved or removed? Discover insights from our Swiss colleagues on this crucial topic. Dive into the details here: https://t.co/dmbrBwlpvE #ActAgainstAmputation #DiabeticFoot #LimbSparing

[Jonathan Misskey @JonMisskey]

Advice for the BC Expensive drugs for rare diseases committee: If you’re taking away a lifesaving medication from a devastated crying mother it’s always important to stop and ask yourself “am I the bad guy here”

[Global BC @GlobalBC]

A group of experts on Batten disease in the United States has penned a letter to B.C.’s health minister and premier, strongly opposing the decision to withdraw funding for 10-year-old Charleigh Pollock.

https://t.co/FoObM3uN76

[Annals of Surgery @AnnalsofSurgery]

Most surgeons agree technical performance should matter in certification—but fear bias, logistics, and subjectivity in high-stakes assessments. A national reckoning is coming.
https://t.co/HdlxJQZEwa