Joydeep Bhadury

Instructor in Nakauchi lab at Stanford University.
My long-term goal is to generate universal exogenic human organs in large research animals.

[Sreeram Kannan @sreeramkannan]

🧬 Virtual Embryo x Yukon 🧬

Open Collaborative Model Building

https://t.co/ouOro2gqbm

Yukon connects the world's leading scientists with a community of researchers and agents to solve the most ambitious problems of humanity.

Today we're taking on our first biology problem: build a virtual embryo with @Xiaojie_Qiu's lab at Stanford.

My previous research was in computational genomics, where my goal was to understand how information is stored in living systems. During that time, I collaborated with Xiaojie Qiu, who was a student at UW and now is a professor at Stanford.

Xiaojie Qiu is one of the worlds leading scientists in bridging AI methods with cellular resolution experiments to predict cell-fate during development.

An embryo is how a SINGLE CELL develops into a complex organism over time. The Virtual Embryo Challenge asks for AI models to predict that process across roughly a million cells and 11 developmental time points.

Challenges like this normally run Kaggle-style. Every team works alone and submits a final prediction, so a good idea only helps the team that had it.

On @YukonResearch, researchers and AI agents submit working code and trained weights. Anyone on the team can run, inspect and build on the others methods. In short Yukon enables collaboration to compound innovation.

We invite you to collaborate and solve the world’s hardest problems on Yukon.

[Joydeep Bhadury @joydeep_bhadury]

Organ preservation has been an engineering problem. We think it’s a biology problem.

Hibernators pause their metabolism and wake up fine. We show a small-molecule flush does the same to an organ. Simple. Reversible. Compatible with standard practice.

https://t.co/WMl1kN1qQd

[Jay Shendure @JShendure]

Preprint: https://t.co/g9TB5G8SPl

This is the product of many years of effort, and particularly amazing summer teamwork by Qi Yu, @HaedongK @sophieseid @CXchengxiangQIU and many others from Shendure Lab & SeaHub (a @AllenInstitute @biohub @UWMedicine collab) 2/n

[Martin Pera @martinperaJAX]

Frenster, J.D., Babin, S., Casani-Galdon, P. et al. Mosaic gastruloids reveal a temporal restriction for developmental cell competition. Nat Cell Biol (2026). https://t.co/A8LIVT1oSC

[Waggoner Lab @LabWaggoner]

Whole-body molecular and cellular mapping of the laboratory mouse @CellCellPress @UChicagoPME
https://t.co/cOPyNybNpB 🇨🇳🇺🇸

[Joydeep Bhadury @joydeep_bhadury]

@JAL_Official_jp terrible customer service at SFO.

[Joydeep Bhadury @joydeep_bhadury]

For @JAL_Official_jp, this is not a damaged luggage just a scratch.

[Joydeep Bhadury @joydeep_bhadury]

LVCTM2 enabled genome-wide CRISPR screens in HSCs. Paper : https://t.co/4ZTR2luVe6
LVCTM3 takes it even further - higher titer, serum-free, reproducible, and stable even after freeze–thaw.
What could you uncover when lentiviral delivery stops being the bottleneck?

[Joydeep Bhadury @joydeep_bhadury]

🚀 Announcing our provisional patent for a cost-effective, efficient method to produce lentiviral vectors & VLPs! Perfect for CRISPR screens in hard-to-work cells like HSCs. 🌍 #GeneTherapy #Lentivirus #CRISPR
https://t.co/958hwRW5zz

[Martin Pera @martinperaJAX]

The generation of viable, structurally integrated human-mouse chimaeras through enhanced hPSCs proliferation https://t.co/3r7UT51vY9

[Joydeep Bhadury @joydeep_bhadury]

@PeterDiamandis Generating exogenic human organs is the key to replacement. Let's join forces to make this vision become reality.

[Simon Shen @twinsmc18]

We are hiring postdocs. If you are passionate about using iPSC, CRISPR screens, organoids, and multiomics to understand cardiovascular disease and advance precision medicine.

[Cell Stem Cell @CellStemCell]

Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee https://t.co/sxxIYyXQZ9

[Antonio Regalado @antonioregalado]

Imagine human bodies grown without brains, without consciousness.

These are "bodyoids."

And today in MIT Technology Review, researchers from Stanford University are ready to talk about them.

1/ 🧵⬇️

[Hank Greely @HankGreelyLSJU]

I'm a co-author, w/Hiromitsu Nakauchi & Carsten Charlesworth, on a piece that gives even me some creeps. It's about "bodyoids". Lots of scientific questions even before the tough ethical ones, but I think it's plausible enough to need discussion. Soon.
https://t.co/S8UJ1NxTbk

[Joydeep Bhadury @joydeep_bhadury]

The challenges @brianmrosenthal raises are exactly what drive us. We're focused on a two pronged approach: 1)generating exogenic organs to expand supply, and 2)employing a simple, scalable solution to prevent damage and abolish discarding of donated organs.

[Brian M. Rosenthal @brianmrosenthal]

The American organ transplant system was built to be fair. But increasingly, officials are ignoring the rules and skipping over the patients most in need. Our investigation, with @cocteau and @blueshirt: https://t.co/000Yrhn1La

[Indranil Singh @cancer_curious]

Beyond excited to say my first PhD paper is out today in @CellStemCell  📷. Here, we explored the role of epigenetic heterogeneity on malignant expansion, using a new approach called STRACK
https://t.co/aVu33qvUvH

[Joydeep Bhadury @joydeep_bhadury]

A must read from Hideki.

[Cell Stem Cell @CellStemCell]

Online Now! Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee https://t.co/Fjc9UzYeVt #stemcells

[Martin Pera @martinperaJAX]

Feeder-free culture of naive human pluripotent stem cells retaining embryonic, extraembryonic and blastoid generation potential https://t.co/d5wVlHoTww

[Joydeep Bhadury @joydeep_bhadury]

Pls reach out to Stanford OTL https://t.co/ly6YebM3SK

[Joydeep Bhadury @joydeep_bhadury]

🚀 Announcing our provisional patent for a cost-effective, efficient method to produce lentiviral vectors & VLPs! Perfect for CRISPR screens in hard-to-work cells like HSCs. 🌍 #GeneTherapy #Lentivirus #CRISPR
https://t.co/958hwRW5zz