@bschermd@TheKetologist Do we know if LMHR is a phenotype affecting a small number of people or is it potentially larger if at a population level most people were metabolically healthy?
@DrSeanBreen@briansoloman MESA Study (2014, Budoff et al.): People with CAC = 0 had a 10-year coronary event rate of ~1–2%, even when they had risk factors like hypertension or high LDL.
Ultra-processed foods need tobacco-style warnings, says scientist. UPFs should also be heavily taxed due to impact on health and mortality, says scientist who coined term @CMonteiro_USP https://t.co/uhUx1WmIRY
☀️It's a helluva good day!☀️
24hrs since our announcement 📢👇 and 151k views - please continue repost (retweet) and share! 🙏
I can never emphasize enough how wonderful you all are in helping make this a reality.
This is truly grassroots #CitizenScience
Ketones May Help Reverse Cognitive Decline
Researchers explored the impact of acute insulin resistance on brain function, focusing on the hippocampus in mice.
They discovered that insulin resistance impairs critical neuronal functions such as synaptic activity, axonal conduction, and network synchronization.
By administering D-βHb, a form of ketones, they were able to restore these functions, suggesting a potential therapy for neurodegenerative diseases like Alzheimer's.
The study highlights the importance of early intervention to prevent the long-term effects of insulin resistance on the brain.
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“D-ꞵ-hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance” by Nathan A. Smith et al. PNAS Nexus
https://t.co/iI69ZNQgAU
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Here is the full length video report into the mysterious 'Global Disinformation Index' and how it censors political speech across Europe and the US. Please share widely, more people need to know.
Avoid these 9 mistakes 👇
1. Losing sight of dreams and falling into work for work’s sake (W4W).
2. Micromanaging and e-mailing to fill time. Set the responsibilities, problem scenarios and rules, and limits of autonomous decision-making—then stop, for the sanity of everyone involved.
3. Working where you live, sleep, or should relax. Separate your environments—designate a single space for work and solely work—or you will never be able to escape it.
4. Not performing a thorough 80/20 analysis every two to four weeks for your business and personal life.
5. Striving for endless perfection rather than great or simply good enough, whether in your personal or professional life. Recognize that this is often just another W4W excuse. Most endeavors are like learning to speak a foreign language: to be correct 95% of the time requires six months of concentrated effort, whereas to be correct 98% of the time requires 20–30 years. Focus on great for a few things and good enough for the rest. Perfection is a good ideal and direction to have, but recognize it for what it is: an impossible destination.
6. Blowing minutiae and small problems out of proportion as an excuse to work.
7. Making non-time-sensitive issues urgent in order to justify work. Focus on life outside of your bank accounts, as scary as that void can be in the initial stages. If you cannot find meaning in your life, it is your responsibility as a human being to create it, whether that is fulfilling dreams or finding work that gives you purpose and self-worth—ideally a combination of both.
8. Viewing one product, job, or project as the end-all and be-all of your existence. Life is too short to waste, but it is also too long to be a pessimist or nihilist. Whatever you’re doing now is just a stepping-stone to the next project or adventure. Any rut you get into is one you can get yourself out of. Doubts are no more than a signal for action of some type. When in doubt or overwhelmed, take a break and 80/20 both business and personal activities and relationships.
9. Ignoring the social rewards of life. Surround yourself with smiling, positive people who have absolutely nothing to do with work. Happiness shared in the form of friendships and love is happiness multiplied.
5 Things All Fools Do (From The Stoics):
1/ Care what other people think (Epictetus)
2/ Wait until tomorrow (Marcus Aurelius)
3/ Act like they’re going to live forever (Seneca)
4/ Suffer before it’s necessary (Seneca)
5/ Make up ‘reasons’ to not do the right thing (MA)
It's been an insane week for AI.
Two GPT-4 level competitors, Google's AI espionage, Elon suing OpenAI, Midjourney drama, open-source robotics, and more.
Here's everything that you need to know: