TXA has important beneficial effects in trauma. In this study we demonstrate how TXA imparts differential effect in females and males after severe TBI specifically in learning, memory and brain edema in a murine TBI model.
https://t.co/nuO7iVGq0L
Joint SPT-AAST Virtual International Case Conference. inaugural virtual session!
October 9, 2023, at 12:00 p.m. ET.
JOIN https://t.co/IVVYAnN7jx
Sessions will recur monthly as part of the existing PTS “Tele-Grand Rounds.”
Every 2nd Monday, 12:00 PM EST
Surgeons from @PennTrauma and @PennNSG hypothesized administration of the antifibrinolytic TXA early, blunts penumbral, blood-brain barrier, leukocyte-endothelial cell interactions and microvascular permeability, in vivo compared to late administration. https://t.co/kCPGJC6T7t
#TXA after #TBI, improves rodent BBB integrity and neurological recovery but only if administered early after injury. Late TXA administration increases rolling leukocyte mobilization to the penumbra
@JPascual2016@UPennTrauma@pennsurgery#JoTACS#MedEd
https://t.co/trLuNDsqeI