Joona Sarkkinen

Opiskelija.

[Anniina Färkkilä @afarkkila]

What are tertiary lymphoid structures (TLSs)? We found evidence of adaptive immunity in #ovariancancer. Check out our #bioRxiv preprint https://t.co/LrewuVpFZa Great collaboration with @jsarkkine @lettipitko

[Joona Sarkkinen @jsarkkine]

Nöyrin kiitos @tiedesaatio väitöstyöprojektilleni myöntämästänne tuesta!

[Jani Huuhtanen @jhuuhtan]

Old friends reunited in CML! 🤝 Our study of a clinical trial shows that the addition of IFN-α curtails the immunological effects of dasatinib in CML, out now in @jclinicalinvest. More about the study and immunology in CML in a slideset below: 🧵 https://t.co/Kr60okbLdp

[Eliisa Kekäläinen @lettipitko]

This work would not have been possible without @QuPath and @FinbbSuomi sample collections. Funding from @EJPRareDiseases made everything possible. Thank you all co-authors and of course @jsarkkine who did all the work! Full article here: https://t.co/oHigf5bY5e

[Eliisa Kekäläinen @lettipitko]

that are central to pathology, are produced in the thymus. MG is an unique opportunity to study autoantibody production in situ! This information could help understand autoantibody production in other diseases as well.

[Eliisa Kekäläinen @lettipitko]

This is our first report from the @taridconsortium - stay tuned, we have much more exciting research into MG and extopic germinal centers in progress. One might wonder why to study a rare autoimmune disease when there are more common ones. In MG we know that the autoantibodies

[Eliisa Kekäläinen @lettipitko]

For me as thymus-enthusiast the most interesting finding was that women woth MG (mostly EOMG) had larger area of Hassall’s corpuscles, those small clusters of epithelial cells in the thymus that nobody really knows what their function is 🧐.

[Eliisa Kekäläinen @lettipitko]

centers are common on EOMG thymi but could also show that the eGC number directly correlates with the patient’s outcome after thymectomy. eGCs were rare in patients over 45 yrs. Pathology of the thymus is thus clearly different in early and late onset diseases.

[Eliisa Kekäläinen @lettipitko]

Myasthenia gravis is a autoimmune disease where autoantibodies targeted againts nerve-muscle junction cause severe muscle weakness. Thymic pathology is often present and esp in early-onset MG, thymectomy alleviates symptoms. We confirmed earlier findings that extopic germinal

[Eliisa Kekäläinen @lettipitko]

New results from our group 🌟, project lead by @jsarkkine and now published in @ModernPathology. We studied thymus histology @FinbbSuomi in rare autoimmune disease myasthenia gravis with generous support from @EJPRareDiseases @taridconsortium https://t.co/oHigf5bY5e. Small🧵

[Anonymous TV 🇺🇦 @YourAnonTV]

JUST IN: #Russian state TV channels have been hacked by #Anonymous to broadcast the truth about what happens in #Ukraine.

#OpRussia #OpKremlin #FckPutin #StandWithUkriane

[Ville Holmberg 🇪🇺 @VilleHolmberg]

Vaikea ymmärtää Etelä-Suomen AVI:n päätöstä liikunta- ja harrastustilojen rajoitusten jatkamisesta. Sairaalakuormitus on ollut stabiili yli viikon. Nämä rajoitukset aiheuttavat merkittävää haittaa ihmisten hyvinvoinnille eikä niitä voi jatkaa vaan varmuuden vuoksi.

[Eliisa Kekäläinen @lettipitko]

Fantasiassani olen päässyt päättämään Suomen koronalinjauksista. Pidän täällä Twitterissä nyt tiedotustilaisuuden uusista linjauksista, pitäkää hatuistanne kiinni! Koska en poliitikko en oikeasti tiedä miten nämä lainopillisesti menevät mutta sitä vartenhan on virkamiehet 💪🏻

[Eliisa Kekäläinen @lettipitko]

Finally now out in @SciImmunology ! Great collaboration and a long road with @IivoHetemaki @nellimarikki @jsarkkine @varjosal @TRIMMprogram @VanhanenReetta and so many others key people not on Twitter! A quick 🧵on our findings https://t.co/PoDkIygZzd

[Joona Sarkkinen @jsarkkine]

@lettipitko Ping. Onneksi ensi viikolla palataan tiukkaan ruotuun!

[The Recount @therecount]

CDC Director Dr. Rochelle Walensky: “Our data from the CDC today suggest that vaccinated people do not carry the virus.”

[Joona Sarkkinen @jsarkkine]

@FISCrossCountry Situation is changing fast and health political pressure must have been huge... image from the official #holmenkollen website

[Joona Sarkkinen @jsarkkine]

@FISCrossCountry No information at https://t.co/UgZDGfrJid , they even still sell tickets via website...

[Eromon Agbomeirele @ersski]

Torilla tavataan!!! #u20fi

[Transfer News Live @DeadlineDayLive]

José Mourinho's payout is expected to be a huge £40m. Forty-million-pounds. (Source: Daily Mail)