Saul Harari

Born/live/work in Brooklyn at NY Community Hospital. GU specialized pathologist.

[Saul Harari @Juggling_path]

I was thinking of possible filler material, or fat necrosis. But looked really weird to me?? CD163 positive and keratin negative. Does this ring a bell for anyone ?

[Saul Harari @Juggling_path]

I have a strange case, was wondering if anybody has seen something like this… 37 F with gyn right labial mass. Cystic lesion with fat. I think shows papillary-like structures lined by histiocytes. And abundant degenerative material

[Saul Harari @Juggling_path]

@slusagar You better believe it 🕺

[Saul Harari @Juggling_path]

@slusagar @VHNguyenMD @AJCPjournal Hahaha great! Thanks for sharing. I was about to publish this 😜

[Saul Harari @Juggling_path]

@MirunaPopescu13 What is 0.196? I wouldn’t know how to follow this rule if I tried 🤣 2/3 of a hpf
Thanks for the posts!

[Saul Harari @Juggling_path]

@slusagar My very NEXT case after your post— atrophic cancer 😂. There are surrounding usual cancer glands so no problem, but out of context, a few these glands at the edge of a core… really tricky. And I think ihc may not help (thank you for all your great posts!)

[Saul Harari @Juggling_path]

@slusagar Pretty…

[Saul Harari @Juggling_path]

@slusagar Great great great :) thank you very much for the links and references. I really appreciate it. This one focus looks angry for NA to me. But I believe that is what this must be. Thank You 👏

[Saul Harari @Juggling_path]

@slusagar Here’s CK7 and some PAX8 looking positive! Very few tubules and some stromal cells. So I think case closed fibromyxoid NA. (NKX3.1, GATA-3, CDX-2 negative)

[Saul Harari @Juggling_path]

@slusagar Thank you so much for the suggestion! History of brachytherapy would make sense too. Areas with benign-looking gland structures, and more atypical stromal looking cells. I saw the mucin and 😱. Added the Pax8 will keep you posted!

[Saul Harari @Juggling_path]

@slusagar Wow 😅

[Saul Harari @Juggling_path]

@leon_metlay @patricksrarebks @BusemBKurt I think there is a book version too. I remember coming across in Rosai somewhere

[Saul Harari @Juggling_path]

@kis_lorand Thanks so much for the suggestions
Finn send out for the expert opinion. See what happens…

[Saul Harari @Juggling_path]

Here’s an interesting case— something I don’t see everyday😳 26F low abdominal/pubic 6 cm. Had a smooth outer border #BSTpath

[Saul Harari @Juggling_path]

@AFOzay Thanks for commenting and for the suggestion. At this point, not knowing what this is I’m sending out to a professional 😜

[Saul Harari @Juggling_path]

@CPremalata I didn’t do the EMA up front (perhaps I should have). Yes very richly vascular. I don’t think location makes sense for ependymoma (anterior pubic/abdominal mass) I am going to send the case out, so didn’t want to hold up any longer without knowing what it is

[Saul Harari @Juggling_path]

@kis_lorand Erg highlights the vessels, very faint staining in tumor cells (looks neg)

I can throw an inhibin or calretinin

There is some tumor necrosis and mitotic activity… so im not sure this is benign.

[Saul Harari @Juggling_path]

@MugniDr Neg for muscle markers and melan-a hmb45

[Saul Harari @Juggling_path]

@ChitownPathMD Ihc doesn’t support either of those …