My resignation letter from CDC.
Dear Dr. Houry,
I am writing to formally resign from my position as Director of the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention (CDC), effective August 28, 2025, close of business. I am happy to stay on for two weeks to provide transition, if requested.
This decision has not come easily, as I deeply value the work that the CDC does in safeguarding public health and am proud of my contributions to that critical mission. However, after much contemplation and reflection on recent developments and perspectives brought to light by Secretary Robert F. Kennedy Jr., I find that the views he and his staff have shared challenge my ability to continue in my current role at the agency and in the service of the health of the American people. Enough is enough.
While I hold immense respect for the institution and my colleagues, I believe that it is imperative to align my professional responsibilities to my system of ethics and my understanding of the science of infectious disease, immunology, and my promise to serve the American people. This step is necessary to ensure that I can contribute effectively in a capacity that allows me to remain true to my principles.
I am unable to serve in an environment that treats CDC as a tool to generate policies and materials that do not reflect scientific reality and are designed to hurt rather than to improve the public’s health. The recent change in the adult and children’s immunization schedule threaten the lives of the youngest Americans and pregnant people. The data analyses that supported this decision have never been shared with CDC despite my respectful requests to HHS and other leadership. This lack of meaningful engagement was further compounded by a “frequently asked questions” document written to support the Secretary’s directive that was circulated by HHS without input from CDC subject matter experts and that cited studies that did not support the conclusions that were attributed to these authors. Having worked in local and national public health for years, I have never experienced such radical non-transparency, nor have I seen such unskilled manipulation of data to achieve a political end rather than the good of the American people.
It is untenable to serve in an organization that is not afforded the opportunity to discuss decisions of scientific and public health importance released under the moniker of CDC. The lack of communication by HHS and other CDC political leadership that culminates in social media posts announcing major policy changes without prior notice demonstrate a disregard of normal communication channels and common sense. Having to retrofit analyses and policy actions to match inadequately thought-out announcements in poorly scripted videos or page long X posts should not be how organizations responsible for the health of people should function. Some examples include the announcement of the change in the COVID-19 recommendations for children and pregnant people, the firing of scientists from ACIP by X post and an op-ed rather than direct communication with these valuable experts, the announcement of new ACIP members by X before onboarding and vetting have completed, and the release of term of reference for an ACIP workgroup that ignored all feedback from career staff at CDC.
The recent term of reference for the COVID vaccine work group created by this ACIP puts people of dubious intent and more dubious scientific rigor in charge of recommending vaccine policy to a director hamstrung and sidelined by an authoritarian leader. Their desire to please a political base will result in death and disability of vulnerable children and adults. Their base should be the people they serve not a political voting bloc.
I have always been first to challenge scientific and public health dogma in my career and was excited by the opportunity to do so again. I was optimistic that there would be an opportunity to brief the Secretary about key topics such as measles, avian influenza, and the highly coordinated approach to the respiratory virus season. Such briefings would allow exchange of ideas and a shared path to support the vision of “Making America Healthy Again.” We are seven months into the new administration, and no CDC subject matter expert from my Center has ever briefed the Secretary. I am not sure who the Secretary is listening to, but it is quite certainly not to us. Unvetted and conflicted outside organizations seem to be the sources HHS use over the gold standard science of CDC and other reputable sources. At a hearing, Secretary Kennedy said that Americans should not take medical advice from him. To the contrary, an appropriately briefed and inquisitive Secretary should be a source of health information for the people he serves. As it stands now, I must agree with him, that he should not be considered a source of accurate information.
The intentional eroding of trust in low-risk vaccines favoring natural infection and unproven remedies will bring us to a pre-vaccine era where only the strong will survive and many if not all will suffer. I believe in nutrition and exercise. I believe in making our food supply healthier, and I also believe in using vaccines to prevent death and disability. Eugenics plays prominently in the rhetoric being generated and is derivative of a legacy that good medicine and science should continue to shun.
The recent shooting at CDC is not why I am resigning. My grandfather, who I am named after, stood up to fascist forces in Greece and lost his life doing so. I am resigning to make him and his legacy proud. I am resigning because of the cowardice of a leader that cannot admit that HIS and his minions’ words over decades created an environment where violence like this can occur. I reject his and his colleagues’ thoughts and prayers, and advise they direct those to people that they have not actively harmed.
For decades, I have been a trusted voice for the LGBTQ community when it comes to critical health topics. I must also cite the recklessness of the administration in their efforts to erase transgender populations, cease critical domestic and international HIV programming, and terminate key research to support equity as part of my decision.
Public health is not merely about the health of the individual, but it is about the health of the community, the nation, the world. The nation’s health security is at risk and is in the hands of people focusing on ideological self-interest.
I want to express my heartfelt gratitude for the opportunities for growth, learning, and collaboration that I have been afforded during my time at the CDC. It has been a privilege to work alongside such dedicated professionals who are committed to improving the health and well-being of communities across the nation even when under attack from within both physically and psychologically.
Thank you once again for the support and guidance I have received from you and previous CDC leadership throughout my tenure. I wish the CDC continued success in its vital mission and that HHS reverse its dangerous course to dismantle public health as a practice and as an institution. If they continue the current path, they risk our personal well-being and the security of the United States.
Sincerely,
Demetre C. Daskalakis MD MPH (he/his/him)
All Kuiper 2 satellites have successfully deployed into space! Congratulations to Amazon and the Project Kuiper team and thank you for again entrusting United Launch Alliance and the Atlas V rocket to deliver.
See our news release: https://t.co/sP3Ak8jr27
When asked if the United States should have a military parade to show off its might, President Eisenhower would respond:
“Absolutely not. We are the pre-eminent power on Earth. For us to try and imitate what the Soviets are doing in Red Square would make us look weak.”
All #Kuiper1 satellites have successfully deployed into space! Congratulations to #Amazon and the #ProjectKuiper team for this amazing achievement and thank you for entrusting United Launch Alliance and the #AtlasV rocket to deliver this critical moment.
News release: https://t.co/wXXBBNrqfV
Massive (68%) cut to NASA astrophysics proposed in WH budget. If this stands, it's the end of American pre-eminence in space science. https://t.co/fhXnXCQ9Hk
Dear World,
I’m an American. I apologize to you all that we put a thoroughly bad, cruel, ignorant madman back in the White House. Many, many Americans apologize. Don’t appease him, don’t coddle him. Stand up to him & punch back at his stupidity.
Best,
An Anti-Trump American
No single person should have the power to do what Trump is doing right now unilaterally dictating world trade & fucking with the world economy. No person should have that power. Certainly not in this country. Shame on u Congressional Republicans for giving it to him. Shame on u.
I know way too many American no longer care about this, but I’ll never stop reminding them of this: Donald Trump is EVERYTHING you teach your children NOT to be. He’s cruel, ignorant, & lawless, he’s a bully, a coward, a cheat, an extreme narcissist, & a pathological liar. You’d never work with him, you’d never work for him, you’d never want any woman you cared about involved with him. He’s a horrible human being. Shame on us for electing him again.
I am all for cutting gov costs, then and now. I'm even more for efficiency
I would have a plan. Ready Fire Aim is not a plan.
Cutting programs without knowing if they would have saved taxpayers more than they cost, or saved lives, is a mistake
Tariffs, cutting programs, agencies and employees ALL AT ONCE, without doing an analysis of the impact on city, towns and states they impact, is going to backfire big time
Some cities have 9 pct or more of their employment as federal workers. Colleges losing millions in funding. Gov contractors and grant recipients having to close their businesses and lay off everyone.
Repeated in city after city. Town after town
What do you think the economic impact on their tax base is ? What do you think happens to home values ? What services will they have to end ?
What about the local businesses ? How many people will lose their jobs and homes because this was done ALL AT ONCE
Cut federal government bloat in an organized fashion and it's great.
Ready Fire Aim and the uncertainty it creates is a huge mistake
Well, this is embarrassing.
Marjorie Taylor Greene tries to push Russian propaganda about Ukrainian nazis, and is completely shut down by Holocaust Historian and the Leading Scholar on Ukrainian Nationalism in America, Dr. Snyder.