Knowuro

Learning platform for urologists, oncologists, and radiotherapists who are passionate about urology.

[Knowuro @knowuro]

We’re excited to announce that our book, Urology: The Last Review 2026, is officially out!📣

It’s already available on our mobile app 📱

We also sent it to print today, with shipping expected to start June 10th.📯
Next post ➡️

[Knowuro @knowuro]

They're here! Shipments start next week (ahead of schedule! 🤩).
Pre-orders go out 1st with a tracking link per email. We ask for your patience as we go through the waiting list.
If you haven't yet, get your copy here 👉 https://t.co/BAtwdrnkiA
Good luck for FEBU! 💪

[Knowuro @knowuro]

Our book Urology Unboxed was recently reviewed by Fatima Kayali from @Uro_News
We are truly delighted to hear that you consider the book “an excellent companion for current and aspiring urology residents.” Thank you so much!🙏
🔗https://t.co/w0r9qW4vDo
📘https://t.co/0hX61WclcM

[Knowuro @knowuro]

@CesarSchamun You can find more information here: https://t.co/xO0tOUpZME 🙂

[Knowuro @knowuro]

We’re excited to announce that our book, Urology: The Last Review 2026, is officially out!📣

It’s already available on our mobile app 📱

We also sent it to print today, with shipping expected to start June 10th.��
Next post ➡️

[Knowuro @knowuro]

A huge thank you to all the reviewers for going the extra mile and making it possible to review the entire book within just two months of the EAU Guidelines 2026 release!
It is always an honour and a pleasure working with all of you!🌟

[Dr. Chacón-Lozsán F .'. @franciscojlk]

🩻Contrast-induced AKI:
one of the biggest myths still shaping clinical decisions

For decades we were taught:

👉 “Contrast damages the kidneys”
👉 “Avoid CT with contrast in CKD”
👉 “Hydrate, protect, delay imaging if needed”

But what if… most of this is wrong?🤔

->The uncomfortable reality

Modern evidence shows:

👉 Low-osmolar contrast rarely causes true nephrotoxicity
👉 Even in CKD, AKI, and ICU patients
👉 The risk is often overestimated—or nonexistent

So where did the fear come from?

📍 1950s high-osmolar contrast (actually toxic)
📍 Poorly controlled observational studies
📍 “Creatinine rise = contrast injury” assumption

👉 Correlation became causation
👉 And the dogma stayed

⚠️What recent data tells us

✔ No difference in AKI rates with vs without contrast
✔ No benefit from bicarbonate, NAC, or aggressive hydration
✔ Even ICU and AKI patients show no worsening outcomes

->Translation to real life

👉 The patient was going to develop AKI anyway...Not because of contrast!!

->The real problem: “Renalism”

👉 Avoiding necessary imaging
👉 Delaying diagnosis
👉 Choosing inferior tests

And that leads to:

❌ Missed PE
❌ Delayed sepsis source control
❌ Worse outcomes

->Clinical mindset shift

Instead of asking:

👉 “Will contrast harm the kidneys?”

We should ask:

👉 “Will NOT doing the scan harm the patient?”

->Who still deserves caution?

✔ eGFR <30
✔ Severe hemodynamic instability
✔ Multiple nephrotoxins

Even then:

👉 Optimize volume
👉 Minimize dose
👉 Don’t delay critical imaging

🤓Bottom line

✔ Contrast nephrotoxicity exists… but is rare
✔ The fear is bigger than the risk
✔ The harm of NOT imaging is often greater

In critical care

👉 We don’t treat creatinine
👉 We treat patients

And sometimes…

👉 The most dangerous thing is NOT the contrast

👉 It’s hesitation.

📃Reference
Florens N, Demiselle J.
Kidney360 7: 445–449, 2026. doi: https://t.co/CWzi7WC9Wx

[Knowuro @knowuro]

Hey urologists, time to get your favourite playlist ready 🎶

[Knowuro @knowuro]

Another UROfact for the week!

Phosphodiesterase type 5 inhibitors include: sildenafil, tadalafil, vardenafil, and avanafIl.

Sources: https://t.co/rKq2TjW6k9 and https://t.co/6vv2z9ZAvP

[Knowuro @knowuro]

Thank you for the overwhelming support!

We are excited to begin work on the new edition!

If you need access to the content of the last review 25, it is still available in our App.

[Knowuro @knowuro]

Urofact of the day!

#urology

[Knowuro @knowuro]

@Nuzhat_FH @amorgado4 @andrea_cocci Hello! No, we only have it as book or on our App.

[Knowuro @knowuro]

Finally, it’s here! 🎉
The 2025 edition is now ready to order 👉https://t.co/2ySfdAe035
Thrilled to welcome @amorgado4 and @andrea_cocci to our reviewers’ board.
A big thank you to all our reviewers for their dedication in bringing this new edition to life! 📚✨

[Knowuro @knowuro]

Great review of the complications associated with an ileal conduit. 👌

[Luis G. Medina @LuisMedinaMD]

New review on ileal conduit complications —A great resource for anyone managing cystectomy patients.
@f_eskenazi_MD @SamerJDT @DoctorSotelo @MUSC_Urology @complic_MDPI @USC_Urology

[Knowuro @knowuro]

Another 30 cases are live in the app, bringing the total to 60! 🤩
Whether you are new to urology, or resident preparing for your board exam, these cases are a great way to test yourself.
“Urology in Practice” is a unique digital book including imaging.
https://t.co/qgINSzxVye

[Knowuro @knowuro]

Yuhuu! 🎉 Our new book Urology in Practice is out!
The first 30 study cases to practise are now live on our app — 70 more on the way!
A big thank you to @Mohamedendourol for contributing images to some of the first cases! 🙏

👉https://t.co/ZUfnFleGzS

[Knowuro @knowuro]

Hello! 👋
Diagnosing a colovesical fistula is often challenging and often requires multiple invasive and costly tests. The poppy seed test, however, should not be overlooked—it is cheap, accurate, and an ideal initial consideration for evaluating a suspected colovesical fistula.

[Knowuro @knowuro]

@ankitraj0019 Our plan is to release the first batch of cases in October, and then gradually add more over time.

[Knowuro @knowuro]

Our 📚 library is growing 👀

We are working on our next book: Urology in Practice. A collection of cases structured for learning step-by-step and sharpening your skills — ideal for preparing before oral exams like FEBU part 2.

Coming very soon!

[Knowuro @knowuro]

Hello! 👋
Spinal cord compression is a cancer emergency 🚑 seen in up to 20% with vertebral mets. Prostate cancer causes blastic (radio-opaque, painful, fewer fractures) METs, while renal cancer causes lytic (bone loss, fracture-prone) METs.

[Knowuro @knowuro]

Hello! 👋

This year, Spanish translations of our uro-oncology flowcharts were created as learning materials for the CONTIGO course in Spain.

They are freely available on our website for Spanish-speaking doctors. 🙂👇

https://t.co/3pKzASJFiU

[Inês Santiago @dr_inessantiago]

While updating the PCA chapter of my book Urology: the Last Review (@knowuro) with @JGomezRivas, we came across something worth diving in – the new EAU risk classification for PCA.
Want to know more?
Freshly published in European Urology. See link 👇
https://t.co/7qKTztxlTx