Karine

Teacher.Longhauler.Currently on pause. French-Welsh 🇨🇵🏴󠁧󠁢󠁷󠁬󠁳󠁿
#CovidLong March 2020.
#TreatLongCovid
#LongCovid
#apresJ20

[Karine @koat71]

#LongCovidAwarenessDay
#ConfrontLongCovid
Le 14 mars 2020, je suis tombée malade, depuis j'ai un #CovidLong.
Ma santé s'est détériorée, j'ai perdu mon emploi, ma vie sociale. Mener une vie normale me manque.
Ceci est ma nouvelle vie.

[Harry Spoelstra @HarrySpoelstra]

There are plenty of world-class L0ngC0vid experts far smarter than I am.

But I bring something they don’t: I’m a CV surgeon and endovascular specialist. I’ve had hearts, lungs, arteries, and other organs literally in my hands. I’ve seen their insides, healthy and ravaged, with my own eyes.

That gives me one brutal, irreplaceable edge: I can take the science and translate it straight into the living, bleeding reality of human anatomy.

And what I see coming is ugly.

You, personally and as a society, are in for one hell of a shock.

Read this 🧵👇

If you keep minimising SARSCoV2, refuse to protect yourselves, and keep swallowing the lies of pseudo-experts chasing money or psychiatrists salivating over a fresh FND goldmine… you’re walking straight into disaster.

Tell every last one of them to https://t.co/rw58iRjUf4 off!

Then follow the hard, unfolding science.👇

Your organs don’t care about opinions. They only care about damage. And the damage is already stacking up, be it momentarily maybe still clinically "silent"! #AvoidSars2 #AvoidReinfections

[Zdenek Vrozina @ZdenekVrozina]

Does the brain always return to baseline after COVID?
A new multimodal MRI study suggests the answer may be - not always.
After infection, some brains may remain in a different network state - and we still do not know if that state is temporary, compensatory, or maladaptive🧵

[Long Covid Advocacy 💙 @LongCovidAdvoc]

We have guest writer Dr Elke Hausmann examining the controversial Levinovitz WIRED article which has sparked significant concern for its portrayal of Long Covid, recovery narratives, and brain retraining approaches.

🎙️Audio available
https://t.co/p2Tpc5lq4j

[Kelly @broadwaybabyto]

You wouldn’t tell someone with cancer they could cure themselves with mind body therapies

You wouldn’t say those with HIV made themselves sick with negative thoughts

The psychologizing of patients with complex chronic illness is one of the most damaging parts of being disabled

[Long Covid Advocacy 💙 @LongCovidAdvoc]

One of the concerning framings of the Levinovitz WIRED article is the deep lack of understanding about PEM (& outing a professor in the process)!

Dr Elke Hausmann (retired GP & with lived experience) addresses this brilliantly in her article.

https://t.co/fA3I9euF4O

[Kelly @broadwaybabyto]

Alan doesn’t believe Long Covid exists, yet Wired permitted him to write extensively on the subject.

If you’re not capable of understanding the basic premise of the condition, you’re not qualified to write about it.

His piece harms the entire chronic illness community.

[ApresJ20 - Association Covid Long France @apresj20]

🧵Une nouvelle étude américaine publiée dans JAMA Network Open estime que le #CovidLong pourrait toucher près d’1 personne infectée sur 6.

Soit environ 15 millions d’Américains

Bien plus que ce que montrent les chiffres officiels.

#ApresJ20

[Kelly @broadwaybabyto]

We are gaslit by friends, family and the medical profession

We have to fight for a diagnosis, fight for treatment, fight for support and fight misinformation

It’s exhausting and it should not be necessary

We aren’t “protecting the illness narrative”.

We’re trying to change it

[Dr. Sean Mullen @drseanmullen]

The hardest thing about COVID isn’t the science.

It’s the invoice.

Accepting the evidence means paying for years of miscalculations, bad assumptions, social conformity, and public certainty.

Most people would rather dispute the bill than pay it.

[PolyBio @polybioRF]

Said Dr. Mark Painter in a recent episode of PolyBio’s Lab Visits: “What we’re seeing in a third of people with Long COVID, maybe more, is evidence that T cells recognizing either SARS-CoV-2—or in some different people, herpesviruses—are persistently activated. Which is suggestive that those viruses are present somewhere in the body.”

Listen to the full interview here: https://t.co/g3CnbSqNsl

[Laura Miers @LauraMiers]

The problem with articles like the Wired one is LongCovid patients aren’t the intended audience. These articles aren’t meant for us. They are for our families, our doctors, our employers, & our elected officials, & they are used to harm us.

[PACO @PacoOnPause]

Long COVID is an existential threat to all of the psychiatrists who have loudly attached themselves to pseudoscientific explanations for the illness. I've been saving quotes and have some funny (horrifying) ones, that I think are important to preserve for historical accuracy.

[Harry Spoelstra @HarrySpoelstra]

Retinal microvascular alterations consistent with endothelial dysregulation in paediatric post-COVID-19 syndrome: A prospective matched-cohort study

🚨More “hidden” post-COVID damage in children!

Kids with long COVID show blood-vessel damage in their eyes, persistent, with partial & slow reversibility in some, still clearly abnormal months after one infection (retinal scans prove it)!

➡️German study design:
- Prospective matched-cohort; 58 children (7–17 yrs) with paediatric post-COVID-19 syndrome (chronic phase) vs. 58 healthy controls (matched age/sex/BMI),
- Retinal vessel analysis (static: CRAE/CRVE/AVR + dynamic flicker vasoreactivity) at baseline, and ~14-week follow-up,
- Single-infection chronic PCS kids,

➡️Main findings:
- Markedly wider central retinal arterioles (+28.1 μm, p<0.001) and venules (+21.7 μm, p<0.001) + higher AVR (+0.038, p=0.005), independent of BP or confounders,
- Pattern = endothelial dysregulation,

➡️Longitudinal changes:
- No overall group improvement at follow-up,
- Kids with largest baseline venular dilation & reduced flicker response showed greatest recovery,
- Longer follow-up + reduced symptoms → venular narrowing & AVR improvement,

➡️Implication:
- First in-vivo evidence of persistent microvascular alterations in paediatric PCS, detectable non-invasively,

➡️Conclusion (paper):
- “This study provides the first in-vivo evidence of altered retinal microvascular parameters in children and adolescents with PCS… persistent alterations in microvascular regulation several months after SARS-CoV-2 infection… heterogeneous, time-dependent changes… some patterns consistent with partial normalisation.”

‼️So paediatric post-COVID-19 syndrome causes long-lasting endothelial dysfunction in the microvasculature, visible months after infection, confirming a biological, vascular basis for kids’ persistent symptoms (not psychosomatic or transient).

This isn’t “mild” anymore. It never was!

This is measurable microvascular damage and remember: a second COVID infection DOUBLES their risk of Long COVID (Lancet Infect Dis 2026, RR 2.08).
#AvoidSars2 #AvoidReinfections #ChildrenCovid19
https://t.co/ggQ3taMKnf
https://t.co/rR6KTdiHif

[Dr Elisa Perego @elisaperego78]

There are hundreds of thousands of publications on SARS-CoV-2 infection. They demonstrate multi-system pathology in acute and Long Covid through some of the most sophisticated scientific approaches in medical history.
These are irrefutable facts.

[Amy @alexandrite113]

If LC and ME/CFS are due to the brain being "stuck in a feedback loop of fight or flight," then why are we not allowed to give blood? Why does our blood damage muscle tissue that's exposed to it? (See study👇🏼)

Maybe it’s Maybelline. Maybe it’s fucking mitochondrial damage.

[Dara in Chains @DarainChains]

Five Years of Biological Receipts: How Chronic SC2 Destroys the Vascular System and Brain

For over 5 years, corners of the medical establishment have attempted to reduce a catastrophic, viral physical crisis down to anxiety, somatic symptom disorder, or an emotional attachment to labels. Meanwhile, the international scientific community has spent those same five years compiling an undeniable, structural ledger of organic damage.

PolyBio Research Foundation and the Long COVID Research Consortium (LCRC) have made one thing perfectly clear. This is a structural, endovascular, and neuroimmune war. It is not a psychological crisis.

How Chronic SC2 dismantles the vascular system and the brain over a multi-year horizon:

Tissue Persistence & Hidden Viral Factories

The virus doesn't clear after the acute phase. Digital transcriptomics and deep tissue biopsies show that SC2 viral RNA (antisense ORF1ab RNA, which indicates active replication) and Spike protein persist in deep tissue reservoirs including the gut wall, bone marrow, and lymph nodes years after initial infection. This ongoing cellular presence acts like an active factory, keeping the immune system locked in an inflammatory loop that drops virons directly onto vascular tissue.

The Vascular Toll

Continuous immune activation hits the cardiovascular infrastructure.

Endothelial Injury:
Current clinical data demonstrates a profound microvascular endotheliopathy, where the delicate endothelial cells lining the body’s smallest blood vessels are systematically injured, inflamed, and degraded.

Fibrin-Amyloid Microclots:
PolyBio's work with scientists like Dr. Resia Pretorius has mapped the widespread presence of anomalous fibrin-amyloid microclots and infected activated platelets. These dense, breakdown-resistant clots physically choke the microcapillaries, cutting off oxygen delivery to deep tissues and causing widespread cellular hypoxia.

NETs:
Innate immune cells (neutrophils) are hyper-activated, spitting out webs of DNA (NETs) that further clog the vascular highway and drive tissue degradation.

The Brain Attack: Perfusion & Leaky Barriers

When the microvascular highway is choked, the brain pays the price.

Hypoxia & Reduced Flow:
Studies confirm significantly reduced cerebral and microvascular blood flow. The brain is quite literally gasping for oxygen because clogged, narrowed capillaries cannot deliver adequate perfusion.

Blood-Brain Barrier Collapse:
Endovascular inflammation breaks down the tight junctions of the BBB. When the protective wall leaks, peripheral cytokines and inflammatory debris bleed directly into the central nervous system.

Neuroinflammatory Steady State:
Advanced neuroimaging (such as dual PET-MRI imaging by PolyBio-supported researchers like Dr. Michael VanElzakker) reveals active, neuroinflammation. Neural-derived exosomes show markers of severe astrocyte turnover. The brain is forced into a hyper-reactive inflammatory steady state, triggering profound cognitive deficits, verbal fluency drops, and severe dysautonomia.

🛑 Psychology Full Stop

When a patient has a leaky blood-brain barrier, amyloid microclots choking their capillaries, vascular compressions, and active virus in tissues, psychiatry and psychology are the wrong medical disciplines.

A psychologist cannot talk a fibrin-amyloid microclot out of a capillary.
Cognitive behavioral therapy cannot repair an injured endothelial lining or stop a viral reservoir in the bone marrow from churning out toxic proteins. Mindset tools for patients suffering from cerebral hypoperfusion and tissue hypoxia is a severe failure of basic clinical logic.

Reframing a measurable, multi-systemic vascular firestorm as an issue of identity is an act of clinical avoidance. Patients do not need coping to accept their own cellular disintegration. They need hematologists, vascular surgeons, immunologists, and targeted meds. The debate over semantics is over, the era of hard vascular mapping is here.

[Mike Hoerger, PhD MSCR MBA @michael_hoerger]

Brain retraining does not fix blood vessels.

[Long Covid Advocacy 💙 @LongCovidAdvoc]

We have written to the editors @WIRED &amp; requested:
🔹Editorial Review
🔹Apology
🔹Right of Reply
🔹Review to investigate whether the Levinovitz article meets WIRED standards for fair &amp; evidence-based reporting in health &amp; disability.

📨 Letters can be sent to: [email protected]

[Todd Davenport @sunsopeningband]

I didn't have it on my calendar to do any writing this week. That...changed.

Unscheduled post on the Substack, up now. https://t.co/bpxMEnZgEK

[The Vertlartnic @TheVertlartnic]

Researchers Find New Long Covid Cure Using Light From Gas