Koelle Lab

We study the ecological, evolutionary, and within-host dynamics of RNA viruses using quantitative approaches. @EmoryUniversity Department of Biology

[Koelle Lab @KoelleLab]

Excited to share our recent preprint on quantifying pandemic potential from experimental transmission studies, spearheaded by grad student Elizabeth Somsen in my group and in collab with Troy Sutton & lab at Penn State and Anice Lowen at Emory: https://t.co/pOGBZqi4Ki.

[Koelle Lab @KoelleLab]

Hope to post again in less than a year :)

[Koelle Lab @KoelleLab]

Collaboration with Lucas Ferreri and the Lowen lab at Emory to look at influenza virus evolution and dispersal during infection within a host: https://t.co/P6uAoJMMjS

[Koelle Lab @KoelleLab]

Fortunate to collaborate with Rustom Antia and Jim Bull on an analysis focused on the question: Why do respiratory viruses evolve antigenically while viruses undergoing systemic replication do not? https://t.co/SueakoGpiy

[Koelle Lab @KoelleLab]

A fun analysis with David Rasmussen focused on seeing if incomplete purifying selection impacts/biases our estimates of epidemiological parameters in phylodynamic analyses: https://t.co/FiTjNHA2B0 (thankfully, it doesn't bias estimates much at all!)

[Koelle Lab @KoelleLab]

And while I'm on tweeter (once in a blue moon), here are some relatively recent papers from our group!

[Koelle Lab @KoelleLab]

Congratulations to Dr. Yeongseon Park for her successful PhD defense on Friday, March 7, 2025!

[Koelle Lab @KoelleLab]

(We think this new approach is preferable to existing approaches - some of which we've developed - because it uses a different subset of viral sites to estimate transmission bottleneck sizes and is less prone to underestimation of bottleneck sizes.)

[Koelle Lab @KoelleLab]

We just posted a preprint on a new approach for estimating transmission bottleneck sizes. Spoiler alert: we confirm bottleneck sizes for influenza virus and SARS-CoV-2 to be tiny using the new approach: https://t.co/JeIbayuuAe

[Koelle Lab @KoelleLab]

Congratulations @park_yeongseon and @m_a_martin 🎉

[Michael Martin @m_a_martin]

So excited this work led by @park_yeongseon with @KoelleLab
is finally out! We show that you can use sequence data to infer epidemiological dynamics (e.g. R0) of emerging pathogens w/o trees by fitting models to the observed segregating sites trajectories. https://t.co/9tSGKbdJuy

[Koelle Lab @KoelleLab]

#eeid2023
Transmission bottleneck and disease severity

[EEID2023 @eeid2023]

Dr. Katie Koelle from Emory University 🦠

[Will Ratcliff @wc_ratcliff]

And now with a more accurate title! Also a gift link, so it should not be behind a paywall.

https://t.co/r0WLrHGRFi

[Dr. Ketaki Ganti Wiser, PhD @ketakiganti]

Our paper on influenza reassortment in mammals is out now on @NatureComms! Congratulations to all our collaborators!https://t.co/ufQNjyNP5f @anice_lowen @LucasFerreri1 @KoelleLab @CRP_FLU_UGA @Juaco1802 @Aivlys87 @juergenricht @CEIRRNetwork #LoveVirology

[UMich Ecology and Evolutionary Biology @UMichEEB]

This week's EEB Thurs Seminar features ALUM Dr Katia Koelle @KoelleLab presenting Using genetic data at multiple scales to understand constraints on viral adaptation. 3pm, 1010 Bio Sci Bldg and Zoom live, see poster
#eventalanche #Genetics #diseases

[Koelle Lab @KoelleLab]

Second PhD defended from the Koelle lab this week was from @m_a_martin. Mike not only did a phenomenal quantity of work, but it was of high quality as well! Mike collaborated with many folks, @SternLab @AnnePiantadosi @Ahmed_HBabiker among others. Congrats!!

[Koelle Lab @KoelleLab]

For the second preprint announcement of the day, we’ve updated our earlier manuscript on using segregating sites trajectories of viral sequence data for epidemiological inference, which was led by @park_yeongseon. https://t.co/HPmqUAW38y

[Koelle Lab @KoelleLab]

This was a highly collaborative project with (undergrad!) Jack Lin, Julie Zhu, Ruston Anita, @anice_lowen, and @dbweissman

[Koelle Lab @KoelleLab]

Our recent work on the variolation hypothesis with regards to SARS-CoV-2 and mask wearing is now up on medRxiv. We show that mask wearing reduces the e probability of infection but does little to reduce severity given infection. https://t.co/3UILRRKChe

[Koelle Lab @KoelleLab]

Congratulations Dr. Allman 🎉

[Koelle Lab @KoelleLab]

It’s PhD Defense day for @brent_allman!

[Daniel Weissman @dbweissman]

congratulations to Dr. @brent_allman on his amazing PhD defense! i've been very lucky to get to co-advise brent with @KoelleLab