Our paper on estimating the expected number of African and European genealogical ancestors for a typical African American (born btwn 1960-1965) is out in this month's issue of GENETICS. Stay tuned for a thread and a series of excellent write-ups from GENETICS, USC, and Stanford.
We offer an individual-level interpretation of polygenic score (PGS) transferability across genetic ancestries:
PGS accuracy varies individual-to-individual across the genetic-ancestry continuum, even in populations usually labeled as homogeneous.
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https://t.co/xqwyKskqbq
Check out our latest paper in @Nature! We unveil the fascinating variation of individual polygenic scoring accuracy across the genetic ancestry continuum!