Kyle Knouse, Ph.D.

Co-Founder / Director @elsiebio. Full time chemist. Part time adult.

[Kyle Knouse, Ph.D. @KyleKnouse]

@nilshomer @threadreaderapp unroll

[Kyle Knouse, Ph.D. @KyleKnouse]

@2jamielynn Making America great by doing absolutely nothing except spewing lies and drawing crowds together during a pandemic. Sounds great.

[Jake Yeston @JakeYeston]

In @ScienceMagazine this week, @BaranLabReads expands the generality of their P(V) platform for selective oligonucleotide synthesis https://t.co/r6WFNajImM

[Baran Lab @BaranLabReads]

Appearing today in @ACSCentSci is an outlook on P(V) chemistry written with the BMS team: https://t.co/BPXDfXTGYa

[Kyle Knouse, Ph.D. @KyleKnouse]

@BowRiver4 @annkope @BaranLabReads @ChemRxiv @EastgateMartin @NataliaMPadial @Julien07 It will be available from @SigmaAldrich in the near future! Feel free to shoot us an email if you’d like a small sample before it’s available commercially.

[Kyle Knouse, Ph.D. @KyleKnouse]

@madihfletch @benchling

[Kyle Knouse, Ph.D. @KyleKnouse]

It’s a P(V) world and we’re just living it in. The fully P(V) approach from #bmschemistry gave 5.8 x yield of these otherwise challenging molecules and enabled toxicology delivery! https://t.co/QUgM3fQkPQ

[Martin Eastgate @EastgateMartin]

Great opportunity to join a company at the very start of its journey!!!!

[Kyle Knouse, Ph.D. @KyleKnouse]

@Julien07 @ATlili1 @auvergnerhalpes @CNRS @CNRS_dr07 @ICBMSLyon @FLUORrismo Woot woot!!

[Kyle Knouse, Ph.D. @KyleKnouse]

@BaranLabReads If you don’t want to wait for @elonmusk just come to Mauna Kea summit, little oxygen, reddish earth and freezing temperatures. Should name it the almost Mars experience.

[Kyle Knouse, Ph.D. @KyleKnouse]

@DonnaBlackmond @ScrippsGradPrgm @BaranLabReads Thanks Donna!!

[Kyle Knouse, Ph.D. @KyleKnouse]

@wmwuest @EmoryUniversity Awesome! Congratulations, Bill! Well deserved.

[Baran Lab @BaranLabReads]

In 2016, with @EastgateMartin and the @bmsnews team we set out to simplify the way Oligonucleotides therapeutics (OTs) are made. Access to a 3-10-3 LNA/DNA gapmer with 4 different P-linkages had pushed the limits of known chem. Today we report a solution: https://t.co/hSsZXFg3DJ

[Kyle Knouse, Ph.D. @KyleKnouse]

The final version of the manuscript appeared online today!

[Baran Lab @BaranLabReads]

Modify DNA as if it were a simple alcohol derivative: Possible now with SENDR, appearing today in @ACSCentSci : https://t.co/XK6v0U1Gr2 For a behind-the-scenes look at SENDR and bioconjugation, visit Open Flask: https://t.co/HvffswyQce

[Kyle Knouse, Ph.D. @KyleKnouse]

@elonmusk how long before we can expect the “Lab-on-a-Tesla”? Autonomous, contact free, testing robot that can be deployed to hotspots? Context: https://t.co/0oDxbRdvxT

[Kyle Knouse, Ph.D. @KyleKnouse]

@jimcramer how is no one talking about $NLST

[Kyle Knouse, Ph.D. @KyleKnouse]

@jimcramer this is worth looking at! https://t.co/G0bvuQjOoU.

[Kyle Knouse, Ph.D. @KyleKnouse]

@realDonaldTrump History says Trump's low approval rating is unlikely to move https://t.co/FDclCwjGy4

[Kyle Knouse, Ph.D. @KyleKnouse]

@BPMonia stay tuned for the final version which will incorporate some heavily @ionispharma inspired experiments!

[The Dawson Group @Dawson_Group]

In this latest addition of collaborative work with @baranlabreads, we present SENDR with this shared tweet thread!

https://t.co/e2IrE4aFBE