This is freaking huge: For the first time, a AI-assisted personalized mRNA cancer treatment has succeeded in a Phase 3 trial.
Moderna and Merck sequence each patient’s tumor and compare it with their healthy DNA. AI then helps identify which of the tumor’s mutations are most likely to trigger an immune response.
From those targets, Moderna produces an individual mRNA treatment encoding up to 34 neoantigens, The earlier Phase 2 trial followed patients with surgically removed high-risk melanoma for five years:
- 68.8% remained cancer-free, compared with 49.1% on Keytruda alone
- 49% lower risk of recurrence or death
- 59% lower risk of distant metastasis or death
Now the much larger Phase 3 trial involving 1,137 patients has also succeeded.
Absolutely incredible. Dario was right: cancer will be cured in just a few years!
Chinese RAM is starting to catch up with the memory used in Western gaming PCs.
Colorful has managed to run Chinese-made DDR5 at 9,000 MT/s, which is a very high speed for modern RAM.
It can also achieve good latency, chinese memory has been tested at DDR5-6000 with CL28/CL30, similar to the low-latency RAM commonly used in gaming PCs.
China’s biggest memory maker, CXMT, is also increasing production, and Chinese-made RAM is already appearing in some laptops.