The reversibility paradox: profound organ dysfunction can coexist with survival of most cells through critical illness.
Could ordered work reallocation help cells during a bioenergetic crisis?https://t.co/2V8xFP27S2 #CriticalCare#Bioenergetics
The reversibility paradox: profound organ dysfunction can coexist with survival of most cells through critical illness.
Could ordered work reallocation help cells during a bioenergetic crisis?https://t.co/2V8xFP27S2 #CriticalCare#Bioenergetics
In our new paper in @alzdemjournals we find an activation of the neuroprotective branch of the kynurenine pathway associated with slower progression in AD @lowatne @mariaksnes @lassegiil @TheFangGroupUiO
@lowatne @engelski@MariusMyrstad@TWyller@Oslounivsykehus@VestreViken This could have potential as memantine may blocks QA. Still, NMDAR hypofunction is a model of schizophrenia and with long-term (days) high QA, what about less NMDAR-glutamate interaction or more NMDAR internalization? Memantine on top? Early IDO-inhibition avoids these issues.