Last Week in Medicine 🎙️

Review of #internalmedicine literature to keep you up to date || #podcast by @sjenkinsmd @aruppmd #medtwitter #FOAMed

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode! We talk about anticoagulation in cirrhosis, beta blockers in MI, finerenone in HFpEF, continuous infusion of antibiotics, cefepime vs zosyn, and secondary prophylaxis for SBP. Check it out! https://t.co/BQRGXwB7GQ

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode! Does metformin prevent long COVID? Should we transfuse thrombocytopenic patients before CVC placement? DOAC or LMWH for cancer thrombosis? Should patients with a stroke due to AF start oral AC early or later? Check it out! #medtwitter https://t.co/AmVFJpvn0p

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode! Dr. Joel Topf, aka @kidney_boy, joins us to talk about a new study he co-authored of over 22,000 patients with hyponatremia. We talk about rapid correction of sodium and the risk of ODS, and lots of other hyponatremia pearls. #MedTwitter
https://t.co/XdVxT6Uspl

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode! Today we talked to Dr. Adam Spivak, HIV expert, on the DoxyPEP study published earlier this month. Check it out! #medtwitter #foamed #IDtwitter #doxypep https://t.co/ngCaF5YyE0

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode with Dr. Sarah Gilligan and ⁦⁦@doc_BLocke⁩! Do thiazides prevent kidney stones? What is the role of steroids in pneumonia? What are the biggest changes in the COPD guidelines? Can we really use oral antibiotics for endocarditis? https://t.co/fYzVPtlKvg

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode! Today we talk to ⁦@DrMitaHopp⁩ about the optimal duration of antibiotics for febrile UTI in men. We also review the new guidelines for lower GI bleeding and a paper looking at risk of persistent AKI after contrast exposure. #medtwitter https://t.co/Hvj2osx4tY

[Last Week in Medicine 🎙️ @lastweekinmed]

New episode of the podcast! We talk about the CLOVERS early vasopressor study in septic shock, torsemide vs furosemide in CHF, aspirin for VTE prophylaxis and haloperidol for delirium #medtwitter https://t.co/cX3eTjB25b

[Last Week in Medicine 🎙️ @lastweekinmed]

In this systematic review and meta-analysis, the efficacy of doxycycline was comparable to macrolides or fluoroquinolones in mild-to-moderate CAP. https://t.co/KS2ep3u3vU

[Last Week in Medicine 🎙️ @lastweekinmed]

Of 43,070 patients tested for Legionella, only (1.5%) tested positive. The strongest predictors of a positive test were a local outbreak (OR 3.4), June–October occurrence (OR, 3.4), hyponatremia (OR, 3.3), smoking (OR, 2.4), and diarrhea (OR, 2.0). https://t.co/lqxWyGkfIJ

[Last Week in Medicine 🎙️ @lastweekinmed]

This study demonstrates that emphysema is often present before spirometry findings become abnormal, particularly among Black men.
https://t.co/j71ovORrSn

[Last Week in Medicine 🎙️ @lastweekinmed]

Postoperative AF after noncardiac surgery is associated with similar risk for thromboembolism compared with nonoperative AF. https://t.co/xvjlATJ78E

[Last Week in Medicine 🎙️ @lastweekinmed]

In hospitalized patients with COVID-19 requiring supplemental oxygen by low-flow, high-flow, or non-invasive ventilation, baricitinib plus remdesivir and dexamethasone plus remdesivir resulted in similar mechanical ventilation-free survival by day 29 https://t.co/Z8vgpHBbtG

[Last Week in Medicine 🎙️ @lastweekinmed]

In patients hospitalized with COVID-19, baricitinib significantly reduced the risk of death but the size of benefit was somewhat smaller than that suggested by previous trials. https://t.co/J5BVt3Jav2

[Last Week in Medicine 🎙️ @lastweekinmed]

In this cohort study, the median time to first antimicrobial administration for sepsis decreased by 37 minutes from 2013 to 2018, and antimicrobial use, days of therapy, and broadness of coverage declined among patients with potential infection. https://t.co/StjFeDkpdQ

[Last Week in Medicine 🎙️ @lastweekinmed]

In patients undergoing hip or knee arthroplasty for osteoarthritis, aspirin compared with enoxaparin resulted in a significantly higher rate of symptomatic VTE, including below-knee VTE. https://t.co/VLzEzog3nK

[Last Week in Medicine 🎙️ @lastweekinmed]

Hospitalization with COVID-19 both before and during vaccine availability was significantly associated with a higher risk of venous thromboembolism, but not arterial thromboembolism, vs hospitalization with influenza in 2018-2019. https://t.co/jf9k90UOFh

[Last Week in Medicine 🎙️ @lastweekinmed]

Sabizabulin resulted in a 25% absolute reduction in deaths compared with placebo in hospitalized patients with moderate to severe Covid-19 at high risk for ARDS and death, with a lower incidence of adverse and serious adverse events compared with placebo. https://t.co/Yg9hz8jZj5

[Last Week in Medicine 🎙️ @lastweekinmed]

Treatment with a polypill containing aspirin, ramipril, and atorvastatin within 6 months after myocardial infarction resulted in a significantly lower risk of major adverse cardiovascular events than usual care. https://t.co/BHwISnPngL

[Last Week in Medicine 🎙️ @lastweekinmed]

The addition of acetazolamide to loop diuretic therapy in patients with acute decompensated heart failure resulted in a greater incidence of successful decongestion. https://t.co/ubaV9sr8k0