Seoul National Univ.
Seoul, Korea (Republic of).
Researches on liver disease; signal transduction; membrane protein dynamics; immuno checkpoint proteins.
TM4SF5-mediated KEAP1 Regulation in Hepatocytes Irrelevant to NRF2 Expression and Activity Promotes Oxidative Stress and Inflammation to Develop Metabolic Dysfunction-Associated Steatotic Liver Disease https://t.co/K9OsoFdI8Y #International Journal of Biological Sciences
2027년도 한국분자세포생물학회 (KSMCB) 회장 후보로 인사드립니다.
(1) 회원 모두가 의미있고 재미난
(2) 학술활동과 교류가 가능하도록
(3) 투명하고 추진력있게
학회의 발전을 위해 노력하겠습니다.
많은 응원 부탁드립니다.
2027년 KSMCB 회장 후보
기호 2번 이정원 배상
Our TM4SF5 story and its therapeutic modalities are going to be exposured both at #BioUSA 2025 and Bio Korea 2025, with being titled as "First-in-class #TM4SF5 inhibitor for MASH (NASH) and HCC Therapy".
#BioUSA2025#immune checkpoint inhibitor
We got this out, which is about a new role of TM4SF5 as an NK cell immune checkpoint, and includes a TM4SF5-specifix Isoxazole small molecules to interrupt the TM4SF5-mediated SLAMF7 downregulation and NK cell immune exhaustion.
https://t.co/UvXC5UkNNU
Have been at Liver Cancer Summit 2024 by EASL. Got heard two talks importatnly supportive for out current projects and ideas with regards to liver disease including HCC/CCA.
We got this out at this happy X-Mas.
Glucose‐mediated mitochondrial reprogramming by cholesterol export at TM4SF5‐enriched mitochondria‐lysosome contact sites - Kim - Cancer Communications - Wiley Online Library https://t.co/Gh3AWXSNIK
This study shows how TM4SF5 in hepatocytes initiates metabolic dysfunctiins even by 1~2 week high fat diet, with involving abnormal food intake behaviors and orexigenic apelin expression.
https://t.co/G1QxITG9KG
The Novel-Natural-Killer-Cell-Related Gene Signature Predicts the Prognosis and Immune Status of Patients with Hepatocellular Carcinoma https://t.co/3d3tOOOOni